10 Best South America Multiday Tours in September 2026

Choro Trail 3D/2N - September 2026

No booking fees

Best price guaranteed

Embark on an exhilarating adventure through Bolivia's Choro Trail, a must-experience for avid hikers. This guided trek takes you from the mesmerizing Andes Mountains to the lush Amazon rainforest, showcasing diverse landscapes. Marvel at ancient Inca trails, explore vibrant cloud forests, and witness stunning wildlife. Enjoy authentic cultural insights from local guides and savor delicious regional cuisine. Perfect for nature enthusiasts and thrill-seekers, this trek promises unforgettable memories and breathtaking vistas. Book now for an immersive Bolivian journey!

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Camping, Tent

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Challapampa, Sandillani

Duration3 days

From

USD 645

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Galapagos Island Hopping Adventure 7D/6N - September 2026

No booking fees

Best price guaranteed

Discover the Galapagos Islands like never before with a thrilling island-hopping adventure. Snorkel with sea lions, explore pristine beaches, and encounter iconic wildlife, including giant tortoises and blue-footed boobies. Expert guides lead immersive nature walks and captivating boat tours, ensuring every moment is unforgettable. With a balanced mix of relaxation and discovery, this tour offers a perfect blend of excitement and serenity in one of the world's most unique and biodiverse environments. Experience the magic of the Galapagos firsthand!

Adventure

Tour Type

Small Group Tour

Accommodation

Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Galapagos Islands, Isabela Islan

Galapagos Islands, Isabela Island, Isla Santa Cruz, San Cristobal Island, Playa Ochoa

Duration7 days

From

USD 2,318

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Inca Jungle Backpacker Trek to Machu Picchu 4D/3N - September 2026

No booking fees

Best price guaranteed

Embark on an exhilarating four-day journey through the heart of Peru, where breathtaking landscapes and thrilling activities await. Begin in Cusco and traverse through lush jungles and quaint villages, experiencing the local culture and stunning vistas of the Andes. Culminate your adventure with an unforgettable exploration of Machu Picchu, delving into the mysteries of this ancient Incan city.

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Guest House, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Santa Maria, Santa Teresa

Cusco, Santa Maria, Santa Teresa, Aguas Calientes

Duration4 days

From

USD 440

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Taironaka Natural Experience 3D/2N - September 2026

No booking fees

Best price guaranteed

Embark on a scenic journey through Colombia's enchanting coastal landscapes, diving into the natural splendour of Tayrona National Park. Relish a perfect blend of exploration and relaxation with vibrant hikes, stunning beaches, and a charming eco-lodge stay. Ideal for travellers seeking a nature-rich getaway.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Eco Lodge, Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Santa Marta, Taironaka Natural Reserve

Duration3 days

From

USD 519

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Inca Trail Express Trek to Machu Picchu 2D/1N - September 2026

No booking fees

Best price guaranteed

Embark on an unforgettable journey from the ancient city of Cusco to the majestic citadel of Machu Picchu. Traverse scenic mountain paths, explore enigmatic ruins, and uncover the cultural richness of the Inca civilization. This adventure offers a harmonious blend of adventure and history, culminating in breathtaking views that are bound to leave an indelible mark on your soul.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Inca Trail, Cusco, Machu Picchu

Inca Trail, Cusco, Machu Picchu, Aguas Calientes

Duration2 days

From

USD 795

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Colca Canyon Trekking 3D/2N - September 2026

No booking fees

Best price guaranteed

Embark on an unforgettable adventure deep into the heart of Peru with our Colca Canyon trekking experience. Traverse one of the world's deepest canyons, surrounded by breathtaking landscapes and rich biodiversity. Encounter indigenous communities, witness the majestic flight of Andean condors, and relax in soothing natural hot springs. This guided trek offers a perfect blend of cultural immersion and outdoor exploration, providing a unique opportunity to discover the stunning beauty and vibrant heritage of the Peruvian Andes.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay, Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Arequipa, Llahuar Lodge, Sangalle

Duration3 days

From

USD 172

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Puerto Maldonado Amazon Field Station 4D/3N (from Puerto Maldonado) - September 2026

No booking fees

Best price guaranteed

Embark on a thrilling Amazon adventure in Puerto Maldonado, exploring Peru's vibrant rainforest. This immersive 4-day tour offers unforgettable jungle excursions, guided wildlife spotting, and serene canoe rides on pristine rivers. Stay at an eco-friendly field station, enhancing your Amazon experience with deep forest hikes, diverse flora and fauna, and captivating night treks. Perfect for nature enthusiasts and adventure seekers, this unique eco-tour delivers breathtaking encounters with the Amazon's unparalleled biodiversity. Discover the heart of Peru's tropical paradise today!

Rainforest and jungle visits

Tour Type

Small Group Tour

Accommodation

Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Puerto Maldonado, Amazon Lodge Tambopata

Duration4 days

From

USD 546

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Ancascocha Trek - September 2026

Trip customizable

Best price guaranteed

Step out of your regular life, and get back to nature! The Ancascocha Trek in the Peruvian Andes is a remarkable trail that, unlike other more popular trails, remains off the beaten track and away from crowds. Yet don't be put off by its lesser known status. Named by National Geographic as one of 20 dream hikes on the World Best Hikes list, this stunning trek takes you past ancient Inca ruins and through traditional Andean villages such as Chillipahua and the trail's namesake Ancascocha (3,700 m). Here you may briefly share the trail with farmers, shepherds and livestock tending to their daily lives far removed from the tourist crowds of Cusco. Challenge yourself as you climb a number of big passes, including the highest point at the Huayanay Pass (4,650 m). The rewards for your efforts are staggering, with panoramic views across the Andes, cascading waterfalls, crystal blue lakes and the towering 6,266 m Apu Salkantay. At all times, your guide and crew will ensure that the pace is suitable for everyone in the group, taking breaks for rest and food whenever needed. At the end of each of the first two days of hiking, you will arrive at camp to find your high-quality tent already pitched (complete with mattress and pillow), your gear in place, and your crew preparing a sumptuous dinner. After a night under the most incredible starlit skies, you will be woken right on time with a cup of steaming hot fresh coffee or tea, before sitting down for a nutritious and energizing breakfast. All you need for the day of hiking ahead. On the third day, you will spend several hours hiking a portion of the Classic Inca Trail, to the sacred valley town of Ollantytambo. This is likely to be the first time you will see other hikers! Taking the scenic train to Aguas Caliente you will have photo opportunities galore as the train cuts along the valley floor. Your final night will be spent in a comfortable hotel with a group dinner at an excellent local restaurant (drinks not included). Rising as early as you want, your itinerary concludes with a guided tour of Machu Picchu. Witnessing this new wonder of the world is an incredible spectacle that will stay with you forever. Finally, with your camera loaded with photos and your head full of incredible memories, you will take the train back to Cusco transfer back to your hotel.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Tent, Camping

Age Range

5-79 yrs

Operated in

english

Destinations

Cusco, Machu Picchu, Aguas Calientes

Duration4 days

From

USD 690

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Lake Titicaca Catamaran 2D/1N (Puno to Puno) - September 2026

No booking fees

Best price guaranteed

Discover the enchanting beauty of Lake Titicaca aboard a luxurious catamaran, embarking from Puno on an unforgettable journey. Experience breathtaking landscapes and rich cultural heritage as you visit the legendary Sun Island. Delight in traditional dances, savor local gastronomy, and enjoy kayaking in crystal-clear waters. This immersive adventure offers a perfect blend of relaxation and exploration, making it an ideal choice for those seeking an authentic and magical Peruvian experience on the world's highest navigable lake.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Puno, Lake Titicaca

Duration2 days

From

USD 1,592

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Rainbow Mountain Trek - September 2026

No booking fees

Best price guaranteed

Embark on an unforgettable Peruvian adventure with an awe-inspiring Rainbow Mountain Trek by Bamba. Hike through the vibrant landscapes of Vinicunca, marvel at the dazzling color spectrum of the mountains, and immerse yourself in the rich Andean culture. This extraordinary trek offers captivating vistas, opportunities to encounter local wildlife, and stunning panoramic photo spots. Perfect for nature enthusiasts and adventure seekers, this trek promises a unique blend of natural beauty and cultural immersion in the heart of Peru.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco

Duration12 hours

From

USD 77

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Super Sales

Essential Colombia - September 2026

No booking fees

Best price guaranteed

This seven-day adventure from Bogota to Medellin is perfect for those seeking the natural beauty of Colombia, with planned activities and plenty of time to wander at your own pace. Walk along an ecological trail, swim in the rivers at El Marmol and climb the zigzag staircase of El Penol for 360-degree views over Guatape. Visit the capital of Colombia’s mountainous Antioquia Province, Medellin and play tejo with the locals over a pint of local beer or two. Then, in your free time, maybe race down rapids in Rio Claro or explore the street art around Comuna 13 (San Javier) with your group of new friends!

Adventure

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel, Lodge

Age Range

18-35 yrs

Operated in

english

Destinations

Bogota, Medellin

Duration7 days

From

USD 1,010

USD 980

Saving

USD 30

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13% OFF TODAY

Super Sales

Real Bolivia to Brazil - September 2026

No booking fees

Best price guaranteed

Take an adventure in diverse South America on this 25-day trip from La Paz to Rio de Janeiro. See amazing natural wonders, walk the streets of busy cities and meet the charming locals with a leader by your side who knows all the best spots. Tour the city of Colonia del Sacramento, discover why Salta is nicknamed ‘La Linda’ (‘the beautiful’) and tick immersive Buenos Aires off your bucket list with your new group of friends. Witness the magic of the Iguazu Falls, journey through the untamed desert scenery of San Pedro de Atacama and see the otherworldly Salar de Uyuni salt flats. You’ll have plenty of free time to explore each location, and all the logistics are taken care of for you, so you can concentrate on making new connections and discovering new places.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-35 yrs

Operated in

english

Destinations

Rio de Janeiro, La Paz, Buenos A

Rio de Janeiro, La Paz, Buenos Aires, Montevideo, Estancia, Iguazu Falls, Paraty, Ilha Grande, Uyuni, Salar De Uyuni, San Pedro De Atacama, Salta

13% OFF TODAY

Duration25 days

From

USD 4,995

USD 4,361

Saving

USD 634

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Super Sales

Epic South America - September 2026

No booking fees

Best price guaranteed

Experience the full spectrum of South America on this epic 39-day adventure – the perfect way to forge lifelong connections. Follow in the footsteps of ancient people on the Inca Trail in Peru, drive past volcanoes, lakes, llamas and flamingos in the Atacama Desert and marvel at the might of Iguazu Falls. Spend nights on an estancia (farm) in Uruguay and at a homestay on Lake Titicaca, sample Argentinian barbecue in Buenos Aires and roam through the Amazon jungle. With like-minded travel companions and a local leader providing recommendations at every stop, this’ll be a South American expedition like no other.

Adventure

Tour Type

Small Group Tour

Accommodation

Camping, Home-stay, Hotel, Lodge

Age Range

18-35 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Cusco, Pun

Rio de Janeiro, Lima, Cusco, Puno, Amantani, La Paz, Uyuni, Salar De Uyuni, San Pedro De Atacama, Amazon Jungle, Salta, Buenos Aires, Montevideo, Estancia, Iguazu Falls, Paraty, Iguazu Falls, Ilha Grande, Ollantaytambo, Inca Trail

Duration39 days

From

USD 7,250

USD 7,033

Saving

USD 218

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Real Argentina To Brazil - September 2026

18% OFF TODAY

Super Sales

Real Argentina to Brazil - September 2026

No booking fees

Best price guaranteed

Embark on a South American escapade from Buenos Aires to Rio de Janeiro on this 14-day adventure. Soak up the might of Argentina before crossing to the charming city of Colonia del Sacramento, then explore the lively Mercado del Puerto in Montevideo. Spend two nights getting to know the locals on an estancia (farm) in Uruguay, either chipping in with the chores or relaxing in the sun, then marvel at the majesty of Iguazu Falls. Finishing off in the paradise of Ilha Grande and the buzz of Rio de Janeiro, you’ll experience the many sides of South America.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-35 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pa

Buenos Aires, Rio de Janeiro, Paraty, Ilha Grande, Montevideo, Estancia, Iguazu Falls

18% OFF TODAY

Duration14 days

From

USD 2,895

USD 2,387

Saving

USD 508

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All South America Tours in September 2026

Page 16 of 320 Trips in South America during September 2026 with 831 Reviews

Choro Trail 3D/2N - September 2026

Galapagos Island Hopping Adventure 7D/6N - September 2026

Inca Jungle Backpacker Trek to Machu Picchu 4D/3N - September 2026

Taironaka Natural Experience 3D/2N - September 2026

Inca Trail Express Trek to Machu Picchu 2D/1N - September 2026

Colca Canyon Trekking 3D/2N - September 2026

Puerto Maldonado Amazon Field Station 4D/3N (from Puerto Maldonado) - September 2026

Ancascocha Trek - September 2026

Lake Titicaca Catamaran 2D/1N (Puno to Puno) - September 2026

Rainbow Mountain Trek - September 2026

Essential Colombia - September 2026

Real Bolivia to Brazil - September 2026

Epic South America - September 2026

Real Argentina to Brazil - September 2026

Page 16 of 320 Trips in South America during September 2026 with 831 Reviews

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All South America Tours in September 2026

Page 16 of 320 Trips in South America during September 2026 with 831 Reviews

Page 16 of 320 Trips in South America during September 2026 with 831 Reviews