THE 10 BEST Self-guided & Independent Tours and Trips in South America 2025/2026

Buenos Aires to Santiago (via Mendoza) Travel Pass

No booking fees

Best price guaranteed

Embark on an unforgettable journey from Buenos Aires to Santiago, immersing yourself in local culture and breathtaking landscapes. Enjoy wine tasting in Argentina's famed Mendoza region, marvel at the Andes’ majestic beauty, and discover vibrant cities bursting with history, art, and gastronomy. Perfect for adventure seekers and culture enthusiasts, this travel pass offers a seamless blend of city life and scenic wonders. Don't miss this chance to explore South America's most dynamic destinations.

Explorer

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Córdoba

Buenos Aires, Santiago, Córdoba, Mendoza

Duration7 days

From

USD 540

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Panama City to Bogota Travel Pass

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Panama City to Bogota, immersing yourself in vibrant cultures, lush landscapes, and rich histories. This seamless travel pass offers unique experiences, including exploring Panama Canal’s marvels, snorkeling in San Blas Islands’ crystal waters, discovering Medellín's urban transformation, and delving into Bogota’s dynamic arts scene. Perfect for thrill-seekers and culture enthusiasts, this tour promises a diverse blend of activities, ensuring an enriching journey through Central America's hidden gems and Colombia's enchanting urban hubs.

BeachSnorkelingExplorer

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Bogota, Panama City, San Blas Is

Bogota, Panama City, San Blas Islands, Medellin, Manizales, Hacienda Venecia Coffe Farm

Duration10 days

From

USD 1,629

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Cuzco to Lima Express Travel Pass

No booking fees

Best price guaranteed

Embark on an unforgettable adventure through Peru’s iconic landscapes with this thrilling travel pass from Cuzco to Lima. Discover the rich history of the Sacred Valley, the mesmerizing beauty of Machu Picchu, and the vibrant culture of Lima. Enjoy guided tours, scenic bus rides, and immersive cultural experiences. Perfect for adventurers and history enthusiasts, this package offers a seamless blend of majestic ruins, breathtaking scenery, and local traditions. Witness Peru’s magic unfold on this ultimate exploration journey.

SandboardingExplorer

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Lima, Paracas, Puno, Areq

Cusco, Lima, Paracas, Puno, Arequipa, Nazca, Huacachina

Duration12 days

From

USD 864

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All South America Self-Guided Tours and Trips

Page 3 of 31 Self Guided Trips in South America with 50 Reviews

Buenos Aires to Santiago (via Mendoza) Travel Pass

Panama City to Bogota Travel Pass

Cuzco to Lima Express Travel Pass

Page 3 of 31 Self Guided Trips in South America with 50 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Self-Guided Tours and Trips

Page 3 of 31 Self Guided Trips in South America with 50 Reviews

Buenos Aires to Santiago (via Mendoza) Travel Pass

Panama City to Bogota Travel Pass

Cuzco to Lima Express Travel Pass

Page 3 of 31 Self Guided Trips in South America with 50 Reviews