10 Best South America Multiday Tours in October 2025

Peru Encompassed - 20 days - October 2025

No booking fees

Best price guaranteed

Explore the incredibly diverse country of Peru and three of its contrasting landscapes – the Andean mountains, the desert and the Amazon rainforest. Get a taste of Bolivia in La Paz, see condors soar over the Colca Canyon and discover the Lost City of Machu Picchu.

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, Cusco, Sacred Vall

Lima, La Paz, Cusco, Sacred Valley, Machu Picchu, Arequipa, Colca Canyon, Puno, Copacabana

Duration20 days

From

USD 5,845

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4-Day Buenos Aires Adventure Tour - October 2025

Trip customizable

Best price guaranteed

Discover a different side of Buenos Aires that remains largely unexplored. Despite its status as one of the largest metropolises in South America, Buenos Aires presents an array of adventure activities tailored for every adrenaline enthusiast. Embark on a captivating bike tour, meandering through the charming northern neighborhoods, and cap it off with an unforgettable horse ride across the sweeping plains at a traditional Ranch

AdventureBicycle tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration4 days

From

USD 1,768

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Martial Glacier Trekking - October 2025

Trip customizable

Best price guaranteed

A few kilometers northwest of the city, we can find one of the most important attractions of Ushuaia: the Martial Glacier, a natural wonder that has a lot to offer in any season. With our tour, we invite you to live an unforgettable experience, which will take you across mountain paths to reach our final destination, the scenic viewpoint of the glacier, where a great reward expects us: the panoramic view of Los Andes, Ushuaia and the sea

Trekking and HikingGlaciers

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Ushuaia, Tierra Del Fuego

Duration1 day

From

USD 355

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Malba Museum & Walking Tour - October 2025

Trip customizable

Best price guaranteed

In this guided tour you will visit the most classic neighbourhoods of the city and also enter inside of one of the most representative places of Buenos Aires culture, recognized worldwide: the Museum of Latin American Art of Buenos Aires (MALBA). We will walk with our guide to get to know the most representative corners of the districts of San Telmo and Puerto Madero. We will visit the historic Plaza de Mayo and we will be located at the foot of the Obelisk of Buenos Aires

Walking tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 63

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Southern Neighborhoods Bicycle Tour - October 2025

Trip customizable

Best price guaranteed

Get to know Buenos Aires on a different and fun way doing a bike tour through the most historic districts of the city. It won't only be a excursion of the neighborhoods because our guides will tell you more about the history, architecture and life of this metropolis. In this Tour we will be biking the south of the city through the neighborhoods of Puerto Madero, San Telmo and La Boca walking riding by the endless landscapes and the Ecological Reserve of Buenos Aires

Bicycle toursCity sightseeing

Tour Type

Small Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 50

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Lakes Off Road from Ushuaia - Escondido And Fagnano Lakes - October 2025

Trip customizable

Best price guaranteed

Far away from the routine of the conventional excursions, get ready for some serious off-road experiences! Travel in a 4WD vehicle through Tierra del Fuego wild lands on this 8-hour tour from Ushuaia. From above the Andes we’ll get a view of Lago Escondido (Hidden Lake), a little wonder that hides at the bottom of a valley. Afterwards, we visit the enormous Lake Fagnano. In our Land Rover Defender we will go through the forest and across rivers. The guide’s congeniality, the barbecue and the Argentine Malbec shared with travelers from all over the world certainly will be worthy to be remember

Walking tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Ushuaia, Tierra Del Fuego National Park

Duration1 day

From

USD 164

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Florentino Ameghino Dam Tour - October 2025

Trip customizable

Best price guaranteed

Explore a fascinating hydraulic engineering marvel of beautiful colors and ancient walls. Venture on interpretive hikes along nature trails once used by the indigenous people and immerse in nature

Rainforest and jungle visits

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Puerto Madryn

Duration1 day

From

USD 334

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Bike Tour Buenos Aires - North Circuit - October 2025

Trip customizable

Best price guaranteed

Get to know Buenos Aires on a different and fun way: biking through multiple neighbourhoods of the city. The North Circuit combines modernity and history, going by the most prestigious districts, such as Puerto Madero, Recoleta and Palermo

Bicycle tours

Tour Type

Small Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 50

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Shore Excursion: Puerto Madryn City Tour and Sea lions - October 2025

Trip customizable

Best price guaranteed

We'll explore the historic old city of Puerto Madryn with it's shopping center, springs, scenic spots and Punta Loma, a settlement of furry sea lions followed by Playa Punta Este and Paraná, where you can see a sunken ship in midwater

City sightseeing

Tour Type

Small Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

Puerto Madryn

Duration1 day

From

USD 70

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Buenos Aires City Tour & Boat Ride - October 2025

Trip customizable

Best price guaranteed

To see and enjoy Bs As sailing on Rio de la Plata. This is the most complete city tour of Buenos Aires. It will allow you to visit Recoleta, Palermo Woods, Downtown area, San Telmo, La Boca and Puerto Madero. In addition, you can get the best views of the City of Buenos Aires from a whole new perspective: the Rio de la Plata

Boat tours, water sports and marine wildlife

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 72

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Ultimate Galapagos - 10 days - October 2025

No booking fees

Best price guaranteed

GALAPAGOS CRUISE: CENTRAL, SOUTH, EAST & NORTH ISLANDSEncounter sea lion colonies basking on pristine beaches, giant tortoises, iguanas, blue footed boobies and more in the wildlife rich Galapagos islands, on this once in a lifetime 8 day cruise around the remote and beautiful volcanic islands which once inspired Darwin himself. Spending a night before and after the cruise in captivating Quito.

Sailing, yachting and motor boating

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Quito, Isla Santa Cruz, Genovesa

Quito, Isla Santa Cruz, Genovesa Island, Santa Fe Island, San Cristobal Island, Espanola Island, Floreana Island

Duration10 days

From

USD 6,735

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Machu Picchu by Train - 9 days - October 2025

No booking fees

Best price guaranteed

Discover the incredible highlights of Peru, from the buzzing culinary capital of Lima to the dense bio diverse Amazon Rainforest, on this exciting 9 day tour. Visit sacred sites, colourful markets and travel by scenic train through the Andean Mountains. Explore some of Peru’s most enchanting destinations as you visit the mysterious Inca ruins at Machu Picchu as well as the terraced ruins of Ollantaytambo. Spend two nights in the Amazon Jungle learning about some of the numerous species of birds and animal that live here.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Bungalow

Age Range

18-80 yrs

Operated in

english

Destinations

Cusco, Machu Picchu, Lima, Amazo

Cusco, Machu Picchu, Lima, Amazon Peru, Sacred Valley, Puerto Maldonado

Duration9 days

From

USD 2,605

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Galapagos Encounters - 7 days - October 2025

No booking fees

Best price guaranteed

GALAPAGOS CRUISE - CENTRAL, NORTH & EAST ISLANDS: Boasting an incredible array of endemic species from the blue-footed booby to the marine iguana, the Galapagos Islands are a true nature lovers’ paradise. Get up close and personal with the resident wildlife on an unforgettable 5 day cruise of these famed islands. Begin and end your adventure with a night in Quito, Ecuador's charming capital.

Cruise

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Quito, Galapagos Islands, Genove

Quito, Galapagos Islands, Genovesa Island, Santa Fe Island, San Cristobal Island

Duration7 days

From

USD 4,585

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Galapagos Discovered - 6 days - October 2025

No booking fees

Best price guaranteed

GALAPAGOS CRUISE - CENTRAL, EAST & SOUTH ISLANDS: Every year the Galapagos Islands tempt throngs of travellers to its shores in search of unique wildlife and other-worldly landscapes. Explore these volcanic islands on a 4-day cruise aboard the M/C Anahi catamaran. Hopping from island to island, discovering what makes it so special. Start and end your Galapagos adventure with a night in captivating Quito, Ecuador's capital.

CruiseWildlife

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Quito, Galapagos Islands, Espano

Quito, Galapagos Islands, Espanola Island, Floreana Island, Isla Santa Cruz

Duration6 days

From

USD 3,895

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All South America Tours in October 2025

Page 83 of 1,738 Trips in South America during October 2025 with 2,422 Reviews

Peru Encompassed - 20 days - October 2025

4-Day Buenos Aires Adventure Tour - October 2025

Martial Glacier Trekking - October 2025

Malba Museum & Walking Tour - October 2025

Southern Neighborhoods Bicycle Tour - October 2025

Lakes Off Road from Ushuaia - Escondido And Fagnano Lakes - October 2025

Florentino Ameghino Dam Tour - October 2025

Bike Tour Buenos Aires - North Circuit - October 2025

Shore Excursion: Puerto Madryn City Tour and Sea lions - October 2025

Buenos Aires City Tour & Boat Ride - October 2025

Ultimate Galapagos - 10 days - October 2025

Machu Picchu by Train - 9 days - October 2025

Galapagos Encounters - 7 days - October 2025

Galapagos Discovered - 6 days - October 2025

Page 83 of 1,738 Trips in South America during October 2025 with 2,422 Reviews

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Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in October 2025

Page 83 of 1,738 Trips in South America during October 2025 with 2,422 Reviews

Page 83 of 1,738 Trips in South America during October 2025 with 2,422 Reviews