10 Best South America Multiday Tours in October 2025

Salkantay Trek to Machu Picchu 4D/3N - October 2025

(21 reviews )

No booking fees

Best price guaranteed

The trek was very well organized from the beginning to end. I was quite nervous to do it but the team was very motivating and attentive, which I really appreciated. The guide was very informative and the food was great.

Active and outdoor

Tour Type

Small Group Tour

Accommodation

Camping, Tent, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Salkantay, Cusco, Machu Picchu

Salkantay, Cusco, Machu Picchu, Soraypampa, Colcapampa, Aguas Calientes

Duration4 days

From

USD 758

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Ravines, Valleys & Folklore music - October 2025

(7 reviews )

Trip customizable

Best price guaranteed

All in all, we were really delighted with the service that we received from you. Thanks! Our favourite part of the trip was the week we spent in the North West driving ourselves. We would definitely like to do that again and spend more time in some of the villages and towns. Feedback and thoughts on the various activities and places we stayed and visited: I have written reviews on TripAdvisor for most of them, you can find me under the username fractal if youd like to read them We liked all the hotels we stayed in. Each one was just right for its location and suited us perfectly. If we had to pick, probably our two favourites were Hacienda de Molinos in Molinos and Finca Adalgisa in Chacras de Coria. Hacienda de Molinos had great charm and the food was excellent. We loved our room and would have liked to have spent a couple of days there. The Vinas de Cafayate had great views and the room was nice. The food in their restaurant was also quite good.. The Design Suites Hotel in Salta was great.our room on our first couple of nights was nicer than the room we had when we returned.the first room had a better view. The breakfasts were a little boring. La Comarca in Purmamarca was really nice. It had great views of the mountains and was spacious. One thing we did notice..Argentina is a wine country and yet only one or two of the hotels had wine glasses in the rooms.we had to ask!! The agents on the ground were mostly very good.

Natural landmarks sightseeing

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Salta, Cafayate, Calchaquies Val

Salta, Cafayate, Calchaquies Valley, Calchaqui Valley

Duration5 days

From

USD 1,075

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9 Days - The Best of Peru - October 2025

Trip customizable

Best price guaranteed

Join us on this nine-day group tour to discover the historic and natural landmarks of Peru. Starting from Lima, this tour will take you to Cusco, Machu Picchu, Puno and Lake Titicaca before returning back to Lima. Sample the delights of the Peruvian capital city of Lima. Walk on the cobblestone streets of Cusco and see the incredible landscapes of the Sacred Valley of the Incas. Lose yourself among the ruins of Machu Picchu and travel to the spectacular Lake Titicaca, the world's highest navigable lake. And see the Quechua people whose life sways to the rhythm of the quena and the charango. Discover their customs and traditions. Please scroll down to the itinerary section for more details.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay

Age Range

6-70 yrs

Operated in

english, spanish

Destinations

Cusco, Machu Picchu, Lima, Puno

Cusco, Machu Picchu, Lima, Puno, Lake Titicaca, Aguas Calientes, Luquina

Duration9 days

From

USD 1,222

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Ushuaia Hotel Departure Transfer to Airport - October 2025

Trip customizable

Best price guaranteed

Conclude your Ushuaia journey effortlessly with our departure transfer service from your downtown hotel to the airport. Our reliable drivers ensure a smooth ride, allowing you to relax and enjoy your final moments in this southernmost city. Say farewell to Ushuaia stress-free, knowing you'll reach the airport on time and in comfort

Ground transfers

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Ushuaia, Tierra Del Fuego

Duration1 day

From

USD 6

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Full Costa Rica Explorer 14D/13N - October 2025

No booking fees

Best price guaranteed

Discover the ultimate Costa Rica adventure with vibrant wildlife, lush rainforests, and pristine beaches. Experience breathtaking volcano hikes, thrilling canopy zip-lining, and serene hot springs. Indulge in diverse activities, including exploring Arenal Volcano, Monteverde Cloud Forest, and Manuel Antonio National Park. Encounter exotic wildlife, immerse in local traditions, and savor authentic cuisine. Ideal for nature lovers and adventure seekers, this enriching journey promises unforgettable memories. Book now for an extraordinary Costa Rican escape!

AdventureWildlife

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

San Jose, Monteverde Cloud Fores

San Jose, Monteverde Cloud Forest Biological Preserve, Punta Arenas, Tortuguero National Park, Puerto Viejo de Talamanca, La Fortuna

Duration14 days

From

USD 2,776

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Gable Island And Penguin Watching - October 2025

Trip customizable

Best price guaranteed

This full day excursion will take us sailing and hiking to discover one of the wildest and most beautiful places on the Beagle Channel. Our Gable Island excursion is for those who come to Ushuaia searching for the end of the world. Far from the city, this place offers the possibility of exploring the unspoiled nature of Tierra del Fuego. This excursion includes a penguin watching trip to Martillo Island

Wildlife

Tour Type

Small Group Tour

Age Range

5-99 yrs

Operated in

english

Destinations

Ushuaia

Duration1 day

From

USD 453

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Ecuador - Andes to Amazon - October 2025

4.5

(8 reviews )

No booking fees

Best price guaranteed

This was a great trip with a good range of experiences, scenery, nature, culture, communities and food. Our guide was very knowledgeable and great at spotting and identifying birds. She judged exactly the right pace for walks and exploring, enabling everyone to participate fully. Ecuador is a wonderful country to visit and I thoroughly enjoyed the trip.

Active and outdoorExplorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Quito, Guayaquil, Riobamba, Cuen

Quito, Guayaquil, Riobamba, Cuenca, Otavalo, Peguche, Cotopaxi National Park, Tena, Misahualli, Misicocha, Banos

Duration14 days

From

USD 2,760

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3 Day Wine & Dine Tour: Colchagua Valley - October 2025

Trip customizable

Best price guaranteed

Indulge yourself! This Colchagua three-day wine and dine tour is the perfect excuse to treat yourself to a weekend of wine and fine cuisine or the ideal romantic getaway with your partner. Spend three days in the beautiful valley of Colchagua. Fill your time with wine tastings, strolls through the vineyards, sampling the fine dining, and even a horseback ride if you choose. Personalize your trip by choosing either to spend the night in a boutique hotel in the Santa Cruz area or enjoying nature in a cosy countryside lodge. The Colchagua Valley is located approximately 180 km south of Santiago and is one of Chile's best-known wine areas! The area has won various awards for their full-bodied cabernet sauvignons, malbecs, merlots, syrahs and carménères. Despite a calm rural oasis atmosphere, the area has a rich culture and history. Come and experience this wonderful region!

Wine tasting toursFood tours

Tour Type

Private Tour

Accommodation

Lodge, Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Santiago, Colchagua Valley

Duration3 days

From

USD 965

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Machu Picchu Calling - October 2025

Trip customizable

Best price guaranteed

Discover the lost land of the Incas and visit Machu Picchu on this 15 day tour of Peru. Starting in Lima we head south to the Ballestas Islands in the Paracas National Reserve. We get to see a huge array of birds and marine mammals on a boat ride through the islands. The next day we head through the Ica Desert on our way to Peru's wine regoin where we visit a winery before travelling to the Oasis of Huacachina where we have a chance to get our hearts pumping on an exhilarating dune buggy ride before settling down for a relaxing evening of camping under the stars. The next morning we are off to see the mysterious Nazca lines before heading to Arequipa for the night. We spend the next 4 days exploring Colca Canyon, we can select from additional activities like white water rafting, cycling, horse riding and trekking. We then travel to Cuzco where we visit some nearby sites before heading back to our hotel to prepare for our next adventure. We head out early the next morning from Cuzco to the Urubamba Valley from where we begin our 4 day trek along the Inca Trail to the unforgettable Machu Picchu. At the end of our trek we head back to Cuzco by train. The next day is free to explore Cuzco at your leisure, the next day you will be transferred to the airport for your departing flight.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Guest House

Age Range

16-85 yrs

Operated in

english

Destinations

Machu Picchu, Lima, Inca Trail

Machu Picchu, Lima, Inca Trail, Cusco, Ballestas Islands and Paracas National Reserve, Huacachina, Arequipa

Duration15 days

From

USD 4,365

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25% OFF TODAY

Simply Peru - October 2025

4.9

(9 reviews )

No booking fees

Best price guaranteed

As a solo traveller, this was my first experience in a group, and it won't be my last. The whole tour exceeded my expectations and every day had a 'Wow' factor. It was very full on and not a relaxing holiday, but when you're travelling that far, why would you not want to embrace everything that the whole country has to offer?! The accommodation was all very good and in perfect locations for exploring the towns and cities. All were very clean and equipped with everything you could need during your stay. Our guide, Pabel was excellent. Very friendly, helpful, accommodating to our needs and has a true passion for, and a very deep knowledge of his country. He deserves a huge pay rise! A totally amazing trip and I'm already looking at my next destination.

Active and outdoorExplorer

Tour Type

Small Group Tour

Accommodation

Hotel, Guest House

Age Range

16-99 yrs

Operated in

english

Destinations

Cusco, Lima, Machu Picchu, Sacre

Cusco, Lima, Machu Picchu, Sacred Valley, Nazca, Arequipa, Chivay, Puno, Taquile Island

25% OFF TODAY

Duration14 days

From

USD 2,080

USD 1,560

Saving

USD 520

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Bolivian Amazon Pampas Adventure 4D/3N (from Rurrenabaque) - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Bolivian Amazon adventure, exploring the pristine pampas from Rurrenabaque. Witness an incredible array of wildlife—pink river dolphins, caimans, and capybaras—in their natural habitat. Enjoy scenic boat rides, thrilling jungle treks, and authentic cultural encounters. This immersive experience promises birdwatching delights and unique opportunities to swim with dolphins. Ideal for nature enthusiasts and adventure seekers, this tour offers an extraordinary glimpse into the rich biodiversity of the Amazon rainforest.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Lodge, Hostel, Eco Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Rurrenabaque, Pampas

Duration4 days

From

USD 415

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The Ultimate Trek to Machu Picchu: Salkantay Trek 5 Days - October 2025

Trip customizable

Best price guaranteed

Salkantay Trek is a popular alternative to the very-crowded classic Inca Trail. It offers more distance, more mountains, more scenery, and a wider variety of landscapes, but still concludes with a visit to the iconic city of Machu Picchu. As the route does not have as many regulations as the Inca Trail, this also means that it can provide a “back door” trek to Machu Picchu when Inca Trail permits are sold out. This new itinerary, Salkantay Trek to Machu Picchu via Llaqtapata, includes the highlights of the other Salkantay trek, but avoids many of the areas that are becoming crowded with other trekkers. This trip is fully-inclusive, including a guide, accommodation, meals and transportation. Duration: 5 days/4 nights Distance trekked: about 50km Elevation: 1900-4600m Difficulty: Moderate Crowds: Moderate

Trekking and HikingMountains

Tour Type

Small Group Tour

Accommodation

Tent, Hotel, Camping

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Salkantay, Cusco, La Playa, Aguas Calientes

Duration5 days

From

USD 765

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Epic Patagonia - Torres del Paine - 'W' route - October 2025

(5 reviews )

No booking fees

Best price guaranteed

Our guides Roberto and Mauricio were amazing. We thoroughly enjoyed our trek of the W. The guides were knowledgeable, timely, informative, and a ton of fun! Patagonia is filled with endless beauty. Thank you for the trip of a lifetime.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Camping, Hotel, Lodge, Tent

Age Range

16-80 yrs

Operated in

english, spanish

Destinations

Torres del Paine National Park

Torres del Paine National Park, Santiago, Camping Laguna Azul, Camp Los Cuernos, Camp Paine Grande, Camp Grey, Puerto Natales

Duration10 days

From

USD 4,990

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Full Day Rio: Christ the Redeemer, Sugarloaf, City Tour and Buffet Lunch - October 2025

Trip customizable

Best price guaranteed

The tour begins with a visit to Corcovado Hill, where the famous statue of Christ the Redeemer is located, an image that conveys the faith and sympathy of the Carioca people. We'll have the opportunity to make the historic ascent, which will make this experience even more special! Then, we will continue to the top of Sugar Loaf Mountain, riding on the cable car that will give us a privileged view, enjoying the panoramic beauty of this place. We will also visit the Maracana Stadium, the Samba Museum, and the Historic center

Sailing, yachting and motor boating

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Rio de Janeiro

Duration1 day

From

USD 120

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All South America Tours in October 2025

Page 21 of 1,515 Trips in South America during October 2025 with 2,199 Reviews

Page 21 of 1,515 Trips in South America during October 2025 with 2,199 Reviews

Salkantay Trek to Machu Picchu 4D/3N - October 2025

Ravines, Valleys & Folklore music - October 2025

9 Days - The Best of Peru - October 2025

Ushuaia Hotel Departure Transfer to Airport - October 2025

Full Costa Rica Explorer 14D/13N - October 2025

Gable Island And Penguin Watching - October 2025

Ecuador - Andes to Amazon - October 2025

3 Day Wine & Dine Tour: Colchagua Valley - October 2025

Machu Picchu Calling - October 2025

Simply Peru - October 2025

Bolivian Amazon Pampas Adventure 4D/3N (from Rurrenabaque) - October 2025

The Ultimate Trek to Machu Picchu: Salkantay Trek 5 Days - October 2025

Epic Patagonia - Torres del Paine - 'W' route - October 2025

Full Day Rio: Christ the Redeemer, Sugarloaf, City Tour and Buffet Lunch - October 2025

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in October 2025

Page 21 of 1,515 Trips in South America during October 2025 with 2,199 Reviews

Page 21 of 1,515 Trips in South America during October 2025 with 2,199 Reviews