10 Best South America Multiday Tours in October 2025

Cuzco to Lima Express Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure through Peru’s iconic landscapes with this thrilling travel pass from Cuzco to Lima. Discover the rich history of the Sacred Valley, the mesmerizing beauty of Machu Picchu, and the vibrant culture of Lima. Enjoy guided tours, scenic bus rides, and immersive cultural experiences. Perfect for adventurers and history enthusiasts, this package offers a seamless blend of majestic ruins, breathtaking scenery, and local traditions. Witness Peru’s magic unfold on this ultimate exploration journey.

SandboardingExplorer

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Lima, Paracas, Puno, Areq

Cusco, Lima, Paracas, Puno, Arequipa, Nazca, Huacachina

Duration12 days

From

USD 864

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Puerto Maldonado Amazon Superior Lodge 5D/4N (from Puerto Maldonado) - October 2025

No booking fees

Best price guaranteed

Discover the breathtaking beauty of the Amazon Rainforest in Puerto Maldonado with an unforgettable eco-adventure. Experience guided wildlife treks, canopy walks, and river excursions that reveal rare Amazonian species and stunning landscapes. Enjoy luxurious accommodations at a superior lodge, savor local Peruvian cuisine, and immerse yourself in indigenous culture. Perfect for nature enthusiasts and adventure seekers, this Amazon journey offers profound insights into this diverse ecosystem, ensuring a once-in-a-lifetime experience in the heart of the jungle.

AdventureExplorer

Tour Type

Small Group Tour

Accommodation

Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Puerto Maldonado, Amazon Jungle

Duration5 days

From

USD 1,190

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Sacred Valley Trek to Machu Picchu 2D/1N - October 2025

No booking fees

Best price guaranteed

Immerse yourself in the enchanting landscapes of the Andes as you journey from the vibrant city of Cusco to the mystical ruins of Machu Picchu. This adventure-packed itinerary will take you through breathtaking mountain passages, historical Inca sites, and picturesque valleys. Relish guided tours, challenging treks, and awe-inspiring views, wrapping up with an unforgettable visit to the world-renowned Machu Picchu.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Aguas Calientes

Duration2 days

From

USD 672

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Sacred Valley Day Trek - October 2025

No booking fees

Best price guaranteed

Discover the breathtaking beauty of Peru's Sacred Valley with an exhilarating trek that immerses you in ancient Inca culture and stunning landscapes. Explore historic ruins, vibrant local markets, and picturesque villages set against majestic Andean peaks. Enjoy guided tours to iconic sites like Ollantaytambo and Pisac, while experiencing authentic Andean traditions. Perfect for adventure seekers and history enthusiasts, this unforgettable journey offers a unique blend of natural splendor and cultural richness in one of the world's most enchanting destinations.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco

Duration11 hours

From

USD 85

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Bolivian Amazon Pampas Adventure 3D/2N (from Rurrenabaque) - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Bolivian Amazon adventure from Rurrenabaque! Discover the vibrant Pampas teeming with exotic wildlife, including pink river dolphins, capybaras, and caimans. Enjoy captivating activities like piranha fishing, guided hikes, and thrilling boat excursions through lush riverine forests. Savor the authentic Amazonian experience with comfortable eco-lodge accommodations and expert local guides ensuring an immersive, safe, and enriching journey. Perfect for nature enthusiasts seeking an eco-friendly expedition in one of the world's most biodiverse regions.

Adventure

Tour Type

Small Group Tour

Accommodation

Hostel, Lodge, Eco Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Rurrenabaque

Duration3 days

From

USD 381

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Machu Picchu by Train Adventure - October 2025

No booking fees

Best price guaranteed

Immerse yourself in the captivating world of the Incas with this unforgettable journey to Machu Picchu. Begin your adventure in Cusco, travel through the scenic Sacred Valley, and arrive at the awe-inspiring Inca Citadel. With expert local guides, explore the ancient marvel, indulge in a gourmet lunch, and return with memories etched in time.

Trekking and HikingTrain tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco

Duration19 hours

From

USD 532

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Lima to Buenos Aires (via Chile) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on a captivating South American adventure traversing the vibrant landscapes of Lima, Santiago, and Buenos Aires. This immersive journey takes you through Peru, Chile, and Argentina, offering unique experiences such as exploring the Sacred Valley, witnessing the surreal beauty of the Atacama Desert, and savoring world-renowned Chilean wines. Discover the rich cultural heritage of each city, from Lima's historic center to Buenos Aires' tango-filled streets. Ideal for adventurers and culture enthusiasts seeking an unforgettable travel experience.

City sightseeingLocal culture

Tour Type

Group Tour

Accommodation

Hostel, Hut, Home-stay, Bungalow, Hotel, Lodge, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Lima, Arequipa, Cu

Buenos Aires, Lima, Arequipa, Cusco, Luquina, Puno, Copacabana, Paracas, La Paz, Sucre, Potosi, Uyuni, Candelaria, Polques, San Pedro De Atacama, Calama, Valparaiso, Santiago, Mendoza, Córdoba, Huacachina, Colca Canyon

Duration41 days

From

USD 2,771

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Chili River Rafting - October 2025

No booking fees

Best price guaranteed

Discover adrenaline-pumping adventure with an exhilarating rafting experience on the Chili River in Peru! Navigate thrilling rapids set against the stunning backdrop of the Andes Mountains. This unforgettable white-water journey offers a blend of natural beauty, heart-racing excitement, and expert-guided safety. Perfect for both novice and seasoned rafters, this Peru rafting tour promises lasting memories. Join us for a unique outdoor escapade and immerse yourself in this South American gem. Book now for an epic adventure!

RaftingAdventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Arequipa

Duration3 hours

From

USD 33

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Colca Canyon Trekking 2D/1N - October 2025

No booking fees

Best price guaranteed

Explore breathtaking Colca Canyon with an unforgettable 2-day trekking adventure. Immerse yourself in the stunning landscapes of one of the world's deepest canyons, spot majestic Andean condors soaring above, and visit traditional Peruvian villages. This exhilarating hike includes guided treks, cultural encounters, and unparalleled natural beauty. Perfect for adventure seekers and nature lovers, this tour blends excitement with authentic local experiences, ensuring a memorable journey through Peru's awe-inspiring Colca Canyon. Book now for an unparalleled escapade!

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Bungalow, Guest House

Age Range

18-99 yrs

Operated in

english

Destinations

Arequipa, Sangalle

Duration2 days

From

USD 126

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Classic Peru - October 2025

4.8

(32 reviews )

No booking fees

Best price guaranteed

Our tour Leader was brilliant. He was engaging , knowledgeable, Apporachable and very patient. Made the Trip super fun. Itinerary was full on and packed. Would like Explore to consider adding Rainbow Mountain to the Itinerary rather than an option. Did the Trip with my daughter who really enjoyed herself. So there could be a future Explore traveller!!

Active and outdoorRafting

Tour Type

Small Group Tour

Accommodation

Hotel, Guest House, Home-stay

Age Range

16-99 yrs

Operated in

english

Destinations

Cusco, Lima, Machu Picchu, Arequ

Cusco, Lima, Machu Picchu, Arequipa, Chivay, Puno, Lake Titicaca, Sacred Valley

Duration14 days

From

USD 3,080

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Machu Picchu by Train 2D/1N (Sleep in Aguas Calientes) - October 2025

No booking fees

Best price guaranteed

Discover the breathtaking wonder of Machu Picchu with an unforgettable train journey that culminates in exploration. Experience captivating landscapes aboard a scenic train ride, delve into ancient Inca history with guided tours, and unwind in the charming town of Aguas Calientes. This adventure offers an ideal blend of culture, history, and natural beauty. Perfect for those seeking a short, yet immersive experience of one of the world's most iconic archaeological sites.

Getaways and short breaks

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Machu Picchu, Aguas Calientes

Duration2 days

From

USD 483

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Machu Picchu Jungle Trek 4D/3N (Biking Only) - October 2025

No booking fees

Best price guaranteed

Discover an exhilarating adventure in the heart of Peru with an unforgettable biking expedition to Machu Picchu. Pedal through lush jungle landscapes, traverse scenic mountain trails, and marvel at breathtaking ancient ruins on this thrilling journey. Perfect for adrenaline seekers and nature lovers, this tour offers a unique blend of adventure and cultural exploration. Unveil the hidden treasures of the Andes while enjoying guided bike rides and immersive local experiences—an ultimate getaway for your bucket list.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Machu Picchu, Santa Maria

Cusco, Machu Picchu, Santa Maria, Santa Teresa, Aguas Calientes

Duration4 days

From

USD 636

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Iquitos Amazon Jungle Adventure 5D/4N - October 2025

No booking fees

Best price guaranteed

Discover an unforgettable Amazon jungle adventure in Iquitos, offering immersive wildlife encounters, guided rainforest hikes, and serene boat tours. This tour includes vibrant visits to native communities, exploration of exotic flora and fauna, and fascinating night safaris. Guests can enjoy comfortable accommodations while experiencing the pristine beauty of the Amazon River and its rich biodiversity. Ideal for nature enthusiasts and adventurous travelers looking for a unique, eco-friendly escape in the heart of the Peruvian Amazon.

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Amazon Peru, Iquitos, Amazon Lod

Amazon Peru, Iquitos, Amazon Lodge Tambopata, Lima

Duration5 days

From

USD 879

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Iquitos Amazon Jungle Adventure 3D/2N - October 2025

No booking fees

Best price guaranteed

Explore the heart of the Peruvian Amazon with a thrilling jungle adventure in Iquitos. Experience exotic wildlife, guided hikes, and canoe trips through lush rainforests. Marvel at diverse flora and fauna, spot pink river dolphins, and visit indigenous communities. This immersive Amazon journey offers unparalleled opportunities for nature photography and birdwatching. Adventure-seekers and nature enthusiasts will love the unique blend of cultural encounters and breathtaking natural scenery. Book now for a memorable eco-tourism experience in one of the world's most biodiverse regions!

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Amazon Peru, Iquitos, Lima

Duration3 days

From

USD 600

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All South America Tours in October 2025

Page 29 of 515 Trips in South America during October 2025 with 1,053 Reviews

Cuzco to Lima Express Travel Pass - October 2025

Puerto Maldonado Amazon Superior Lodge 5D/4N (from Puerto Maldonado) - October 2025

Sacred Valley Trek to Machu Picchu 2D/1N - October 2025

Sacred Valley Day Trek - October 2025

Bolivian Amazon Pampas Adventure 3D/2N (from Rurrenabaque) - October 2025

Machu Picchu by Train Adventure - October 2025

Lima to Buenos Aires (via Chile) Travel Pass - October 2025

Chili River Rafting - October 2025

Colca Canyon Trekking 2D/1N - October 2025

Classic Peru - October 2025

Machu Picchu by Train 2D/1N (Sleep in Aguas Calientes) - October 2025

Machu Picchu Jungle Trek 4D/3N (Biking Only) - October 2025

Iquitos Amazon Jungle Adventure 5D/4N - October 2025

Iquitos Amazon Jungle Adventure 3D/2N - October 2025

Page 29 of 515 Trips in South America during October 2025 with 1,053 Reviews

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All South America Tours in October 2025

Page 29 of 515 Trips in South America during October 2025 with 1,053 Reviews

Page 29 of 515 Trips in South America during October 2025 with 1,053 Reviews