10 Best South America Multiday Tours in October 2025

Bolivia Explorer 8D/7N - October 2025

No booking fees

Best price guaranteed

Discover Bolivia's breathtaking landscapes and rich cultural heritage on this immersive adventure. Trek through awe-inspiring Andean mountains, marvel at the otherworldly Uyuni Salt Flats, explore the vibrant streets of La Paz, and uncover ancient ruins in Tiwanaku. This journey offers a perfect blend of nature, history, and local experiences, ensuring unforgettable memories. Ideal for nature enthusiasts and history buffs, this comprehensive tour highlights the must-see destinations and hidden gems of Bolivia. Experience the magic of Bolivia like never before!

AdventureWildlifeWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, La Paz, Isla Del Sol, Uy

La Paz, La Paz, Isla Del Sol, Uyuni, Atulcha, Huayllajara

Duration8 days

From

USD 1,241

View Tour

Wild Patagonia for Hikers - October 2025

(5 reviews )

Trip customizable

Best price guaranteed

We just returned from a 5-week trip to South America. The team was AMAZING. They helped us plan a very complex itinerary that included multiple cities in Chile and Peru, a side-trip to Easter Island, Machu Picchu and the sacred valley, and finally Iguazu Falls in Argentina and Peru. The advice they gave and the hotels they chose were truly exceptional. The detailed day-by-day itinerary was very helpful, and all of their in-country partners (e.g., drivers, tour guides) were terrific. Everything went perfectly. Best travel experience ever! Thank you, Analia and Antonella!!!

Trekking and Hiking

Tour Type

Private Tour

Accommodation

Hotel, Camping, Lodge, Tent

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

El Calafate, Ushuaia, Torres del

El Calafate, Ushuaia, Torres del Paine National Park, Punta Arenas, El Chalten, Tierra Del Fuego, Puerto Natales, Patagonia, Perito Moreno Glacier, French Valley, Tierra Del Fuego National Park, Torres Del Paine

Duration16 days

From

USD 4,105

View Tour

Adventures in Patagonia - October 2025

4.6

(23 reviews )

No booking fees

Best price guaranteed

Our leader made sure each and every one of us had the best experience of the countries that he was so passionate and knowledgeable about. They are beautiful and varied with snow capped mountains, glaciers creating large lakes and miles and miles of wide open spaces where a variety of animals such as grey foxes, sheep and guanacos roam. We learned of their history, culture, food, music and people whilst travelling from Buenos Airies to the ‘end of the world’ in Ushuaia and north through Chile. It is an experience I will never forget and would thoroughly recommend to those who love to travel. .

Active and outdoor

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

16-79 yrs

Operated in

english

Destinations

Buenos Aires, Perito Moreno Glac

Buenos Aires, Perito Moreno Glacier, El Chaltén, Ushuaia, Tierra Del Fuego National Park, Punta Arenas, Torres del Paine National Park, Torres Del Paine, El Calafate

Duration14 days

From

USD 5,670

View Tour

Costa Rica Highlights Adventure 8D/7N - October 2025

No booking fees

Best price guaranteed

Embark on an exhilarating Costa Rica adventure, exploring lush rainforests, stunning waterfalls, and vibrant wildlife. Enjoy thrilling activities like zip-lining through canopies, white-water rafting, and soaking in Arenal's hot springs. Discover the rich biodiversity of Monteverde Cloud Forest and unwind on Tamarindo's pristine beaches. This unforgettable journey promises immersive cultural experiences and breathtaking natural wonders, perfect for adventure seekers and nature lovers. Book now and experience Costa Rica's unparalleled beauty and excitement!

AdventureWildlifeWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

San Jose, Tortuguero National Pa

San Jose, Tortuguero National Park, La Fortuna, Monteverde Cloud Forest Biological Preserve

Duration8 days

From

USD 2,164

View Tour

Bolivia Highlights Adventure 14D/13N - October 2025

No booking fees

Best price guaranteed

Explore Bolivia like never before with an unforgettable adventure through its most breathtaking landscapes and cultural wonders. Experience the vibrant city of La Paz, marvel at the surreal Uyuni Salt Flats, journey through the heart of the Amazon rainforest, and discover the rich history of Potosi and Sucre. Immerse yourself in local traditions, witness stunning Andean vistas, and embrace thrilling activities like trekking and wildlife spotting. Embrace the ultimate Bolivian escapade filled with unique experiences and unforgettable memories.

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, La Paz, San Juan, Huayll

La Paz, La Paz, San Juan, Huayllajara, Copacabana, Isla Del Sol

Duration14 days

From

USD 1,686

View Tour

Bolivia Explorer 9D/8N - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure through Bolivia's stunning landscapes with a tour that captures the essence of this diverse country. Discover the surreal Uyuni Salt Flats, explore vibrant La Paz, and marvel at ancient ruins in Tiwanaku. Enjoy thrilling activities like mountain biking down the "Death Road" and immerse yourself in local culture with community visits. This tour offers a perfect mix of natural wonders, historical sites, and adrenaline-pumping adventures, making it a top choice for intrepid travelers.

AdventureWildlifeWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Copacabana, Uyuni, Atulc

La Paz, Copacabana, Uyuni, Atulcha, Huayllajara

Duration9 days

From

USD 1,181

View Tour

Iguazu Falls Adventure 4D/3N (Foz to Puerto) - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure to the breathtaking Iguazu Falls, spanning Brazil and Argentina. Experience exhilarating tours, including hiking lush rainforest trails, boat rides under cascading waterfalls, and exploring diverse wildlife. Witness panoramic views from both countries, with guided tours enhancing your journey. Perfect for nature lovers and thrill-seekers, this tour promises an extraordinary blend of natural wonders and adrenaline-pumping activities. Discover why Iguazu Falls is a must-visit destination on your travel bucket list. Book your adventure now!

AdventureWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Foz Do Iguacu, Puerto Iguazu

Duration4 days

From

USD 784

View Tour

Lima to La Paz Express Travel Pass - October 2025

No booking fees

Best price guaranteed

Discover South America's hidden gems with an unforgettable journey from Peru to Bolivia. Begin in the cultural hub of Lima, explore the enigmatic Nazca Lines, sail on majestic Lake Titicaca, and marvel at the ancient Incan city of Machu Picchu. Experience the vibrant city of Cusco and the bustling markets of La Paz. This adventure promises a blend of history, culture, and breathtaking landscapes, perfect for travelers eager to delve into the heart of the Andes.

City sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Lima, La Paz, La Paz, Arequipa

Lima, La Paz, La Paz, Arequipa, Cusco, Ballestas Islands and Paracas National Reserve, Huacachina, Colca Canyon

Duration15 days

From

USD 902

View Tour

Adventures in Patagonia + Iguazu Extension - October 2025

4.8

(6 reviews )

No booking fees

Best price guaranteed

This is a very active, fast-paced trip with plenty of opportunities for long hikes, amazing scenery and fabulous flora and fauna. Some long journeys, as it is a vast area to cover, but well worth it. An absolutely fabulous experience.

WildlifeActive and outdoor

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

16-79 yrs

Operated in

english

Destinations

Buenos Aires, Perito Moreno Glac

Buenos Aires, Perito Moreno Glacier, El Chaltén, Mount Fitzroy, Puerto Iguazu, Iguazu Falls, Ushuaia, Tierra Del Fuego National Park, Punta Arenas, Torres del Paine National Park, Los Glaciares National Park

Duration17 days

From

USD 7,980

USD 7,710

Saving

USD 270

View Tour

Iguazu Falls Adventure 3D/2N (Foz to Puerto) - October 2025

No booking fees

Best price guaranteed

Discover the mesmerizing Iguazu Falls on this thrilling travel adventure from Foz do Iguaçu to Puerto Iguazú. Immerse yourself in the natural wonder with guided tours of both Brazilian and Argentine sides, exploring lush rainforests and dramatic waterfalls. Enjoy electric boat rides and panoramic vistas, capturing breathtaking moments. Perfect for nature lovers and adventure seekers, this tour promises unforgettable encounters with one of the world's most iconic natural attractions. Book now for an ultimate Iguazu Falls experience!

AdventureWalking toursExplorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Foz Do Iguacu, Puerto Iguazu

Duration3 days

From

USD 516

View Tour

23% OFF TODAY

Super Sales

Galapagos Island Hopping - October 2025

No booking fees

Best price guaranteed

Amazing wildlife, both on land and under the water, is the main drawcard of the remote Galapagos Islands. On this eight-day trip, you’ll explore this otherworldly archipelago on foot and by boat with an expert naturalist guide to lead the way. Swim with sea turtles, see giant tortoises up close, watch sea lions lounge around town and discover fascinating, varied landscapes. Learn about the conservation efforts on Isla Santa Cruz, take a cooking class to make a famed Ecuadorian soup and enjoy multiple snorkelling opportunities, as well as a full-day hike to the second-largest volcanic crater in the world! This trip will have you cruising and exploring by day and relaxing on land by night, with all the logistics taken care of for you.

WildlifeWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Baltra Island, Isla Santa Cruz

Baltra Island, Isla Santa Cruz, San Cristobal Island, Floreana Island, Isla Isabela

23% OFF TODAY

Duration8 days

From

USD 2,520

USD 1,934

Saving

USD 586

View Tour

Peru Highlights Adventure 14D/13N (from Lima) - October 2025

No booking fees

Best price guaranteed

Discover Peru's hidden gems with a thrilling adventure through breathtaking landscapes and ancient ruins. Explore the iconic Machu Picchu, delve into the mystique of the Amazon Rainforest, and experience vibrant local culture in Cusco. Marvel at the Sacred Valley, cruise on Lake Titicaca, and enjoy scenic train rides and impressive Inca architecture. This immersive journey promises unforgettable memories, perfect for travelers seeking authentic cultural experiences and unparalleled natural beauty. Embark on a Peruvian adventure of a lifetime!

AdventureWalking tours

Tour Type

Small Group Tour

Accommodation

Home-stay, Hotel, Hostel, Bungalow, Hut

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Lima, Puno, Aguas Calient

Cusco, Lima, Puno, Aguas Calientes, Huacachina, Arequipa, Colca Canyon, Amantani

Duration14 days

From

USD 1,437

View Tour

Samba & Tango Air-Expedition 14D/13N (from Buenos Aires) - October 2025

No booking fees

Best price guaranteed

Embark on an exhilarating South American adventure with an exclusive air-expedition that takes you from Buenos Aires to the heart of Brazil and Argentina. Experience the vibrant cultures of Samba and Tango as you explore iconic landmarks, indulge in local cuisines, and immerse yourself in rich traditions. Highlights include scenic helicopter flights over Iguazu Falls, guided tours of Rio de Janeiro, and captivating dance performances. Perfect for culture enthusiasts and thrill-seekers, this journey guarantees unforgettable memories.

AdventureWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Il

Buenos Aires, Rio de Janeiro, Ilha Grande, Puerto Iguazu, Foz Do Iguacu, Paraty

Duration14 days

From

USD 5,647

View Tour

27% OFF TODAY

Super Sales

Best of Galapagos - October 2025

(1 review )

No booking fees

Best price guaranteed

Amazing wildlife, both on land and underwater, is the main drawcard of the remote Galapagos Islands. On this ten-day trip through the best of the Galapagos, you’ll uncover the outstanding natural beauty of these islands both on foot and by boat, looking for giant tortoises, sharks, blue-footed boobies, pelicans, seals, iguanas, dolphins, whales and birdlife along the way. Trace Darwin's theory of evolution, go snorkelling across multiple islands, hike up a volcano for the best views and soak up the experience with a group of likeminded travellers and a local leader who knows all the best spots.

WildlifeTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Quito, San Cristobal Island, Flo

Quito, San Cristobal Island, Floreana Island, Isla Isabela, Isla Santa Cruz, Isla Baltra

27% OFF TODAY

Duration10 days

From

USD 4,100

USD 3,007

Saving

USD 1,093

View Tour

All South America Tours in October 2025

67 Trips in South America during October 2025 with 52 Reviews

67 Trips in South America during October 2025 with 52 Reviews

Bolivia Explorer 8D/7N - October 2025

Wild Patagonia for Hikers - October 2025

Adventures in Patagonia - October 2025

Costa Rica Highlights Adventure 8D/7N - October 2025

Bolivia Highlights Adventure 14D/13N - October 2025

Bolivia Explorer 9D/8N - October 2025

Iguazu Falls Adventure 4D/3N (Foz to Puerto) - October 2025

Lima to La Paz Express Travel Pass - October 2025

Adventures in Patagonia + Iguazu Extension - October 2025

Iguazu Falls Adventure 3D/2N (Foz to Puerto) - October 2025

Galapagos Island Hopping - October 2025

Peru Highlights Adventure 14D/13N (from Lima) - October 2025

Samba & Tango Air-Expedition 14D/13N (from Buenos Aires) - October 2025

Best of Galapagos - October 2025

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in October 2025

67 Trips in South America during October 2025 with 52 Reviews

67 Trips in South America during October 2025 with 52 Reviews