10 Best South America Multiday Tours in May 2026

Lost City Trek 4D/3N - May 2026

No booking fees

Best price guaranteed

Embark on an unparalleled adventure into the heart of Colombia’s Sierra Nevada de Santa Marta. Traverse lush jungles and sacred indigenous territories as you seek the legendary Lost City of the Tayrona people. Experience the vibrant biodiversity and rich cultural tapestry, and let nature guide you on this journey of discovery and awe-inspiring vistas.

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Santa Marta, Nazareth, Colombia, Lost City

Duration4 days

From

USD 736

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Andean Discovery - 18 days - May 2026

No booking fees

Best price guaranteed

Discover the highlights of Chile, Bolivia and Argentina on this 18 day private tour, visiting Atacama and the otherworldly Valley of the Moon, Uyuni, the world's largest salt flat and the spectacular Iguazu Falls, before ending in the sultry capital of Buenos Aires.

Explorer

Tour Type

Private Tour

Accommodation

Hotel, Villa

Age Range

18-80 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Santiago

Buenos Aires, Santiago, Santiago, Tupiza, Purmamarca, Salta, Iguazu Falls, San Pedro De Atacama, Laguna Colorada, Uyuni

Duration18 days

From

USD 8,385

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Iguazu Falls Adventure 4D/3N (Puerto to Puerto) - May 2026

No booking fees

Best price guaranteed

Experience an unforgettable journey to Iguazu Falls with this thrilling adventure tour. Immerse yourself in the breathtaking beauty of one of the world’s largest waterfall systems. Highlights include exhilarating boat rides, jungle treks, and exploring the rich biodiversity of Iguazu National Park. Capture stunning panoramic views from both the Argentine and Brazilian sides. Perfect for nature lovers and adventure seekers, this Iguazu Falls tour promises an action-packed itinerary filled with awe-inspiring landscapes and unique wildlife encounters.

AdventureExplorer

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Puerto Iguazu

Duration4 days

From

USD 457

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Holambra City Tour The Flowers City In Sao Paulo - May 2026

Trip customizable

Best price guaranteed

A tour through Holambra’s City also well-known as the Flowers’ city for its abundance on ornamental plants and its distinguished beauty. You’ll get to know the history of this beautiful garden city, different types of flowers, its gastronomy, and its touristic places. It is recommended for those who love nature, flowers, and agriculture

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-100 yrs

Operated in

english

Destinations

Sao Paulo

Duration1 day

From

USD 194

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18% OFF TODAY

Tour Santos and Guaruja - May 2026

Trip customizable

Best price guaranteed

In this tour we will take you to discover the most beautiful coastal cities of São Paulo. We will visit the city of Santos, famous for having the largest seaport in Latin America. Here we will explore its virgin beaches and take a streetcar ride to places of great cultural importance, ending with a panoramic view of the city. Afterwards, we will go to Guarujá, known as the "Pearl of the Atlantic", where we will take a tour of its beautiful beaches, and then enjoy an afternoon of shopping

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-100 yrs

Operated in

english

Destinations

Sao Paulo

18% OFF TODAY

Duration1 day

From

USD 183

USD 150

Saving

USD 33

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19% OFF TODAY

São Paulo City Tour - May 2026

Trip customizable

Best price guaranteed

We invite you to an unforgettable tour of the main tourist attractions, monuments and historical landmarks of the city of São Paulo. We will take a panoramic tour to explore the architectural beauty of traditional and modern buildings, accompanied by professional guides who will help us discover even more of the history and culture that coexist in this city. Come and see what makes São Paulo one of the most vibrant cities in Brazil!

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-100 yrs

Operated in

english

Destinations

Sao Paulo

19% OFF TODAY

Duration1 day

From

USD 113

USD 92

Saving

USD 21

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Puerto Maldonado Amazon Superior Lodge 5D/4N (from Puerto Maldonado) - May 2026

No booking fees

Best price guaranteed

Discover the breathtaking beauty of the Amazon Rainforest in Puerto Maldonado with an unforgettable eco-adventure. Experience guided wildlife treks, canopy walks, and river excursions that reveal rare Amazonian species and stunning landscapes. Enjoy luxurious accommodations at a superior lodge, savor local Peruvian cuisine, and immerse yourself in indigenous culture. Perfect for nature enthusiasts and adventure seekers, this Amazon journey offers profound insights into this diverse ecosystem, ensuring a once-in-a-lifetime experience in the heart of the jungle.

AdventureExplorer

Tour Type

Small Group Tour

Accommodation

Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Puerto Maldonado, Amazon Jungle

Duration5 days

From

USD 1,190

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Private City Tour Embu Das Artes - May 2026

Trip customizable

Best price guaranteed

We will leave the hotel towards the city of Embu, known as the city of arts. The village that emerged in 1,559 is known nationally and internationally as a region of concentration of painters, artisans and sculptors who exhibit their works through 38 galleries, antique shops and the famous Embú das Artes Fair

Explorer

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Sao Paulo

Duration1 day

From

USD 541

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Private Santos Day Trip - May 2026

Trip customizable

Best price guaranteed

We will take you to discover one of the most beautiful coast towns of the Sao Paulo State, with our tour: SANTOS DAY TRIP We will visit the city of Santos, famous for having the biggest seaport in Latin America, we will explore its pristine beaches as well as places of great cultural importance, ending with a panoramic view of the city from the Serrat Mount

Explorer

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Sao Paulo

Duration1 day

From

USD 877

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13% OFF TODAY

Trindade Beach - May 2026

Trip customizable

Best price guaranteed

Join our trip to discover the best beaches of Paraty, in the region of Trindade. It is part of Serra da Bocaina National Park, so you will find more than fifty well-preserved beaches, some which remain almost untouched by the hand of man. In this heavenly landscape, our tour TRINIDADE COAST will take to tour beaches like: Praia do Meio, Praia do Cachadaço, natural pool Cachadaço, Praia do Cepilho and Praia dos Ranchos, where we will hike through the "Mata Atlantica" or dive ourselves into its waters, to discover the life that lives beneath the surface

Explorer

Tour Type

Small Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

Paraty

13% OFF TODAY

Duration1 day

From

USD 46

USD 40

Saving

USD 6

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Ultimate Inca Trail Trek to Machu Picchu 4D/3N - May 2026

No booking fees

Best price guaranteed

Get ready for a once-in-a-lifetime experience that fuses the best of two legendary treks into one epic journey. Begin with the awe-inspiring Lares Trek, where vibrant Quechua communities, steaming natural hot springs, and sky-high mountain passes set the stage for adventure. Then dive straight into the magic of the Inca Trail Express, hiking through lush cloud forests and ancient stone paths before your triumphant arrival at Machu Picchu through the iconic Sun Gate, just as the Incas did centuries ago. This isn’t just a trek. It’s a soul-stirring expedition through time, culture, and jaw-dropping scenery. Lose yourself in the Andes, find yourself in the heart of history. Two epic trails. One unforgettable journey. Are you in?

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Camping, Hotel, Tent

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Huacawasi, Ollantaytambo

Cusco, Huacawasi, Ollantaytambo, Aguas Calientes, Cuzco

Duration4 days

From

USD 943

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14% OFF TODAY

Angra Dos Reis Day Trip With Boat Tour - May 2026

Trip customizable

Best price guaranteed

The tour ANGRA DOS REIS DAY TRIP BOAT TOUR - RIO DE JANEIRO is a perfect excursion, as it give us the opportunity to discover the heavenly islands in Angra dos Reis, through a boat ride that takes us through the beautiful Islands of Cataguases, Lagoa Azul, Araça and Japariz, being able to make stops at each one to enjoy its beaches. The tour is complete with a delicious lunch

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Rio de Janeiro

14% OFF TODAY

Duration1 day

From

USD 72

USD 62

Saving

USD 10

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4-Day Trip San Juan - May 2026

Trip customizable

Best price guaranteed

This 4-day trip to San Juan will let you visit this unique destination outside the conventional itineraries. a place that amazes for its unusual formations and characteristics of the soil. The astonishment of the place and its importance for the study of the archaeological and paleontological sites caused, in the year 2000, its declaration as an UNESCO World Heritage Site. This is how it was created the Ischigualasto Provincial Park with its Triassic sediments, alongside a visit to the Calingasta Valleys and El Leoncito National Park, well-known for their breathtaking landscapes and the most important astronomical complex in South America

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-95 yrs

Operated in

english

Destinations

San Juan, Ischigualasto National

San Juan, Ischigualasto National Park, Talampaya National Park

Duration4 days

From

USD 2,197

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Tigre Delta from Buenos Aires with Brunch - May 2026

Trip customizable

Best price guaranteed

This tour takes you from Buenos Aires to discover the natural jewel of Tigre in half a day. On the way, you will get to know the "North Zone" of the province until you reach Tigre, where you will be able to walk around and get to know the town. You will also sail and get to know the Delta, in its rivers and streams. Then, we will have a stop for a brunch in a restaurant to recharge your batteries and make your stay in Tigre an unforgettable experience

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 365

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All South America Tours in May 2026

Page 14 of 423 Trips in South America during May 2026 with 941 Reviews

Page 14 of 423 Trips in South America during May 2026 with 941 Reviews

Lost City Trek 4D/3N - May 2026

Andean Discovery - 18 days - May 2026

Iguazu Falls Adventure 4D/3N (Puerto to Puerto) - May 2026

Holambra City Tour The Flowers City In Sao Paulo - May 2026

Tour Santos and Guaruja - May 2026

São Paulo City Tour - May 2026

Puerto Maldonado Amazon Superior Lodge 5D/4N (from Puerto Maldonado) - May 2026

Private City Tour Embu Das Artes - May 2026

Private Santos Day Trip - May 2026

Trindade Beach - May 2026

Ultimate Inca Trail Trek to Machu Picchu 4D/3N - May 2026

Angra Dos Reis Day Trip With Boat Tour - May 2026

4-Day Trip San Juan - May 2026

Tigre Delta from Buenos Aires with Brunch - May 2026

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Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in May 2026

Page 14 of 423 Trips in South America during May 2026 with 941 Reviews

Page 14 of 423 Trips in South America during May 2026 with 941 Reviews