10 Best South America Multiday Tours in May 2027

15% OFF TODAY

Black Friday Super Sales

Real Argentina to Brazil - May 2027

No booking fees

Best price guaranteed

Embark on a South American escapade from Buenos Aires to Rio de Janeiro on this 14-day adventure. Soak up the might of Argentina before crossing to the charming city of Colonia del Sacramento, then explore the lively Mercado del Puerto in Montevideo. Spend two nights getting to know the locals on an estancia (farm) in Uruguay, either chipping in with the chores or relaxing in the sun, then marvel at the majesty of Iguazu Falls. Finishing off in the paradise of Ilha Grande and the buzz of Rio de Janeiro, you’ll experience the many sides of South America.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-35 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pa

Buenos Aires, Rio de Janeiro, Paraty, Ilha Grande, Montevideo, Estancia, Iguazu Falls

15% OFF TODAY

Duration14 days

View Tour

19% OFF TODAY

Black Friday Super Sales

Buenos Aires to Rio Explorer - May 2027

No booking fees

Best price guaranteed

Hug the eastern coastline of South America on this 17-day city, countryside and island adventure. Discover Buenos Aires’ eclectic markets at San Telmo, travel to Rio de Janeiro to soak up all the Brazilian party vibes and experience life on an estancia in Uruguay. You’ll have a local leader each step of the way to recommend the best beach or coolest bar, plus a small group of likeminded travellers to share your experiences with. Ready, set – let’s fiesta.

City sightseeingWaterfalls

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Il

Buenos Aires, Rio de Janeiro, Ilha Grande, Colonia Del Sacramento, Tacuarembo, Puerto Iguazu, Foz Do Iguazu, Iguazu Falls, Paraty

19% OFF TODAY

Duration17 days

View Tour

Best Of Argentina, Uruguay & Brazil - May 2027

24% OFF TODAY

Black Friday Super Sales

Best of Argentina, Uruguay & Brazil - May 2027

No booking fees

Best price guaranteed

Journey along the eastern side of South America on this 10-day adventure from Buenos Aires to Rio de Janeiro. Start by sipping yerba mate and exploring the markets of Argentina’s fiery capital before embracing ranch life with horse rides, homecooked meals and campfires at a Uruguayan estancia. Then swap the dusty plains for the subtropical rainforests at Iguazu Falls and see the epic cascades from both the Brazilian and Argentinian sides. Finish in Rio, unwinding on the sandy shores of Copacabana and Ipanema with an ice-cold caipirinha.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Co

Buenos Aires, Rio de Janeiro, Colonia Del Sacramento, Tacuarembo, Foz Do Iguazu, Iguazu Falls

24% OFF TODAY

Duration10 days

View Tour

Santiago To Buenos Aires: Volcanos, Valleys & The Lake District - May 2027

19% OFF TODAY

Black Friday Super Sales

Santiago to Buenos Aires: Volcanos, Valleys & the Lake District - May 2027

No booking fees

Best price guaranteed

Pack your bags and get ready to bounce through South America on this 12-day ride full of wild nature, epic nights, and laid-back lake vibes. Start in Santiago and hop an overnight bus to Pucón, where volcanoes, hot springs, and endless adventure await. Cruise through Chile’s dreamy Lake District with a chill stop in Puerto Varas, then cross into Argentina to explore the outdoorsy paradise of Bariloche. Hike, bike, or just soak it all in — your pace, your way. Wrap things up in buzzing Buenos Aires with tango, steak, and one last big night out. This is South America in full colour, and you’re living it large.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-39 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Pucon, P

Buenos Aires, Santiago, Pucon, Puerto Varas, San Carlos de Bariloche

19% OFF TODAY

Duration12 days

View Tour

19% OFF TODAY

Black Friday Super Sales

Real Bolivia & Argentina - May 2027

No booking fees

Best price guaranteed

Get off the tourist trail on this extraordinary adventure through Bolivia, Chile and Argentina. Kick things off in the Altiplano city of La Paz and check out the potions and artifacts at the local Witches' Market. Journey to the Salar de Uyuni salt flats – one of the most remarkable landscapes on the planet. Drive through the Atacama Desert past volcanoes, lakes, llamas and flamingos, then dip into San Pedro de Atacama in Chile to soak up more desert scenery. Your adventure wraps up in the lively city of Buenos Aires in Argentina, where you’ll sample some local snacks at the market and say goodbye to your new group of friends.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-35 yrs

Operated in

english

Destinations

Buenos Aires, La Paz, Uyuni, Sal

Buenos Aires, La Paz, Uyuni, Salar De Uyuni, San Pedro De Atacama, Salta

19% OFF TODAY

Duration12 days

View Tour

15% OFF TODAY

Black Friday Super Sales

Epic Mexico to Costa Rica - May 2027

No booking fees

Best price guaranteed

From cloud forests and volcanic peaks to sun-drenched island beaches and lost temples, Central America is bursting with natural wonders and converging cultures. On this epic 32-day adventure, you’ll kick off in Mexico’s Playa del Carmen and snake through Belize, Guatemala, El Salvador, Nicaragua and Costa Rica. Relax by colourful architecture in San Miguel, trek to the jungle ruins of Tikal, brush up on your Espanol over an icy cerveza and stay in villages dwarfed by volcanoes. Whether you’re haggling in the markets of Chichicastenango, chilling in a Caribbean town on the Rio Dulce or wandering cobblestone streets in Antigua, you'll be discovering new places and forging lifelong friendships along the way. From ancient Maya ruins to modern nightlife, you’ll explore the sights and sounds of Latin life and dive into the wilds of seldom-seen hotspots.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel, Lodge, Camping

Age Range

18-35 yrs

Operated in

english

Destinations

San Jose, Playa Del Carmen, Rio

San Jose, Playa Del Carmen, Rio Dulce, Antigua, San Jorge La Laguna, Panajachel, Suchitoto, Cerro Verde National Park, Tulum, Leon, Granada, Ometepe, San Juan Del Sur, Monteverde, La Fortuna, Caye Caulker, San Ignacio, Tikal

15% OFF TODAY

Duration32 days

View Tour

15% OFF TODAY

Black Friday Super Sales

Epic Central America - May 2027

No booking fees

Best price guaranteed

It doesn’t get much bigger than this – take on a 45-day adventure enjoying everything Central America has to offer, from Mexico to Costa Rica and all the cool spots in between. Whether you're hitting the waves in El Salvador, trekking the steamy cloud forests in Costa Rica, snorkelling the pristine underwater worlds in Belize or washing down your tacos with mezcal in Mexico, there's no shortage of unforgettable experiences on this trip. You’ll cover six countries, stopping at dozens of towns and beaches and sipping many (many) cervezas. Oh Maya, this is huge.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Hostel, Camping

Age Range

18-35 yrs

Operated in

english

Destinations

Mexico City, San Jose, Campeche

Mexico City, San Jose, Campeche, Valladolid, Playa Del Carmen, Tulum, Caye Caulker, San Ignacio, Tikal, Rio Dulce, Antigua, Lake Atitlan, Oaxaca, Cerro Verde National Park, Suchitoto, Leon, Granada, Ometepe Island, San Juan Del Sur, Monteverde, La Fortuna, San Cristobal De Las Casas, Palenque

15% OFF TODAY

Duration45 days

View Tour

29% OFF TODAY

Black Friday Super Sales

Real Guatemala to Costa Rica - May 2027

No booking fees

Best price guaranteed

From the Guatemalan highlands to the cloud forests of Costa Rica (and all the surf spots in between), you’ll join a new group of soon-to-be friends and roll through four Central American countries for a taste of this diverse region. Discover tropical forests alive with jungle melodies, vast freshwater lakes and active volcanoes – this wildlife-rich pocket of Central America is ready to be explored. Turn your eyes to a volcanic crater in Cerro Verde, spot colourful birds on the facades of Granada, stand in the shadow of the mighty Arenal Volcano and search for sloths among the canopy of Monteverde Cloud Forest. This trip through Guatemala, El Salvador, Nicaragua and Costa Rica is perfect for those who like their adventures 'la forma natural'.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel, Camping

Age Range

18-35 yrs

Operated in

english

Destinations

San Jose, Antigua, San Jorge La

San Jose, Antigua, San Jorge La Laguna, San Juan Del Sur, Monteverde, La Fortuna, Cerro Verde National Park, San Salvador, Leon, Granada, Ometepe Island

29% OFF TODAY

Duration17 days

View Tour

29% OFF TODAY

Black Friday Super Sales

Real Peru to Bolivia - May 2027

No booking fees

Best price guaranteed

With a stay in the heart of the jungle, plenty of pisco sours and some hot and heavy hiking on the Inca Trail, this trip is 15 days of exploring, drinking, eating and sweating (nobody said the trail would be easy, but boy is it worth it). Experience the real Amazon in a proper jungle lodge, follow in the footsteps of ancient people on the Inca Trail to Wonder of the World Machu Picchu and stay with a local family who live in a mud-brick house on the shores of Lake Titicaca. Hit the nightlife in Cusco, sail down the Amazon River in the pitch-black of night (look out for jaguars!) and experience an I’m-so-far-from-home moment with some new friends on an epic trek through Peru to Bolivia.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Lodge, Home-stay

Age Range

18-35 yrs

Operated in

english

Destinations

Lima, La Paz, Puno, Lake Titicac

Lima, La Paz, Puno, Lake Titicaca, La Paz, Puerto Maldonado, Cusco, Ollantaytambo, Inca Trail

29% OFF TODAY

Duration15 days

View Tour

Peru, Bolivia & Argentina Adventure - May 2027

24% OFF TODAY

Black Friday Super Sales

Peru, Bolivia & Argentina Adventure - May 2027

No booking fees

Best price guaranteed

Get to know the cultures and landscapes of three South American countries on this 35-day adventure. Journey through desolate salt flats, lunar-like deserts and vast canyons, then get acquainted with the local life at La Paz’s Witches Market and the floating islands of Lake Titicaca. Uncover the mysteries of the Nazca Lines, wander the historic streets of Cusco and trek the ancient Inca Trail to Machu Picchu, then refuel with empanadas and malbec in Argentina. With stops in Lima, Arequipa, Sucre and Buenos Aires, this trip is packed with fascinating experiences and plenty of free time to make it your own.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Home-stay

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Lima, Cusco, Inca

Buenos Aires, Lima, Cusco, Inca Trail, Puno, La Paz, Sucre, Potosi, Uyuni, Salar De Uyuni, Tupiza, Paracas, Tilcara, Nazca, Arequipa, Chivay

24% OFF TODAY

Duration35 days

View Tour

South America Tours in May 2027

Page 6 of 85 Trips in South America during May 2027 with 466 Reviews

Real Argentina to Brazil - May 2027

Buenos Aires to Rio Explorer - May 2027

Best of Argentina, Uruguay & Brazil - May 2027

Santiago to Buenos Aires: Volcanos, Valleys & the Lake District - May 2027

Real Bolivia & Argentina - May 2027

Epic Mexico to Costa Rica - May 2027

Epic Central America - May 2027

Real Guatemala to Costa Rica - May 2027

Real Peru to Bolivia - May 2027

Peru, Bolivia & Argentina Adventure - May 2027

Page 6 of 85 Trips in South America during May 2027 with 466 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

South America Tours in May 2027

Page 6 of 85 Trips in South America during May 2027 with 466 Reviews

Page 6 of 85 Trips in South America during May 2027 with 466 Reviews