10 Best South America Multiday Tours in April 2026

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Essential Colombia to Chile - 21 days - April 2026

No booking fees

Best price guaranteed

GROUP TOUR (FOR AGES 18 - 55): Set out on the ultimate South American journey with this 21 day tour, packed with bucket-list experiences, breathtaking landscapes, and thrilling adventures! Take in Medellin and Bogota, trek through the Andes to the legendary Machu Picchu, take a boat ride on Lake Titicaca, and explore the vibrant streets of La Paz. Cross the otherworldly Uyuni Salt Flats in a 4x4, marvel at flamingo-filled lagoons, and soak in high-altitude hot springs. Finally, chase adrenaline in the Atacama Desert, from cycling in the Lunar Valley to stargazing under one of the clearest night skies on Earth.

Explorer

Tour Type

Group Tour

Accommodation

Camping, Guest House, Hostel, Hotel, Sleeper Bus

Age Range

18-55 yrs

Operated in

english

Destinations

Medellin, Santiago, Machu Picchu

Medellin, Santiago, Machu Picchu, Cusco, Puno, La Paz, Uyuni, San Pedro De Atacama, Santiago, Salento, Cali, Bogota, Inca Trail

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Duration21 days

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Super Sales

Real Bolivia to Brazil - April 2026

No booking fees

Best price guaranteed

Take an adventure in diverse South America on this 25-day trip from La Paz to Rio de Janeiro. See amazing natural wonders, walk the streets of busy cities and meet the charming locals with a leader by your side who knows all the best spots. Tour the city of Colonia del Sacramento, discover why Salta is nicknamed ‘La Linda’ (‘the beautiful’) and tick immersive Buenos Aires off your bucket list with your new group of friends. Witness the magic of the Iguazu Falls, journey through the untamed desert scenery of San Pedro de Atacama and see the otherworldly Salar de Uyuni salt flats. You’ll have plenty of free time to explore each location, and all the logistics are taken care of for you, so you can concentrate on making new connections and discovering new places.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-35 yrs

Operated in

english

Destinations

Rio de Janeiro, La Paz, Buenos A

Rio de Janeiro, La Paz, Buenos Aires, Montevideo, Estancia, Iguazu Falls, Paraty, Ilha Grande, Uyuni, Salar De Uyuni, San Pedro De Atacama, Salta

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Duration25 days

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Rafting in Mendoza - April 2026

Trip customizable

Best price guaranteed

Enjoy the best rafting experience in Mendoza during this 5-hour-long program. Your journey down the river starts in Potrerillos with a safety briefing and an introduction to rafting. After you wear the necessary gear supplied by us, your descent starts through the rapids of the Mendoza River. Splash your way through 10 class III rapids plus 5 class II rapids while enjoying the beautiful landscape of the Andes Mountains. The Mendoza River is a giant stream of water that makes its way down the mountains, layers of which were created 65 million years ago when this area was inhabited by prehistoric animals. The starting point of this adventure is located near the International Route 7, while it ends 12km downstream at Potrerillos Lake. The trip back to the starting point takes 20 minutes by road. Throughout the adventure, you will be under the supervision of guides who have received International Rescue Certification courses and will be accompanied by kayakers for safety reasons. We will drop you back at your hotel in Mendoza afterwards.

Rafting

Tour Type

Private Tour

Accommodation

Hotel

Age Range

9-79 yrs

Operated in

english

Destinations

Mendoza

Duration5 hours

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Central America Youth Expedition - 40 days - April 2026

No booking fees

Best price guaranteed

GROUP TOUR (FOR AGES 18-39): Explore Mexico, Guatemala, Belize, and Costa Rica on this 40-day tour, starting in Mexico City with its Aztec heritage, and moving through Oaxaca's markets and mezcal distilleries. Journey through Sumidero Canyon and San Cristobal de las Casas, then visit Isla Holbox's beaches and Mayan sites like Chichen Itza and Tulum. Continue to Bacalar's lagoon, Belize's reefs, and Caye Caulker for snorkelling, before experiencing Mayan cooking in Guatemala and exploring Tikal and the Candelaria Caves. Embark on a 4x4 adventure into the highlands, followed by a hike and swim in blue pools, with a traditional Mayan lunch. Visit Chichicastenango and Panajachel by Lake Atitlán, then take a boat to San Marcos and San Juan La Laguna. Hike Mayan Face Mountain at sunrise, then trek Acatenango volcano before heading to Costa Rica. Explore San Jose, La Fortuna, Arenal Volcano, Rio Celeste, and Rincon de la Vieja, before visiting Liberia, a pottery village, and Samara’s beaches. Conclude with a visit to Esterillos, Manuel Antonio National Park, the Crocodile Bridge, and San Jose.

Explorer

Tour Type

Group Tour

Accommodation

Camping, Home-stay, Hotel

Age Range

18-39 yrs

Operated in

english

Destinations

Mexico City, San Jose, Isla Holb

Mexico City, San Jose, Isla Holbox, Playa Del Carmen, Chichen Itza, Bacalar, Caye Caulker, Flores, Coban, Panajachel, San Juan La Laguna, Antigua, Acatenango, La Fortuna, Oaxaca, Rincon de la Vieja Volcano National Park, Playa Samara, Esterillos, Tehuantepec, San Cristobal De Las Casas, Cancún

Duration40 days

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Super Sales

Machu Picchu & Galapagos - April 2026

No booking fees

Best price guaranteed

Combine two of the great adventure destinations in one trip: Machu Picchu, one of the New Wonders of the World, and the wildlife-watching haven of the Galapagos Islands. Starting in Peru, we explore the Inca empire, first visiting Cuzco and the nearby ruins, before taking the train through mountains and cloud forest to the once-lost city of Machu Picchu – hiking a section of the Inca Trail if you wish. It’s then off to the Galapagos, exploring land and sea in search of sharks, giant tortoises, sea lions and more with an expert naturalist guide.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Cusco, Quito, Floreana Island, I

Cusco, Quito, Floreana Island, Isla Santa Cruz, Ollantaytambo, Aguas Calientes, San Cristobal Island, Isla Lobos

Duration15 days

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Patagonia Bike Safari: Wilderness & Wildlife - April 2026

Trip customizable

Best price guaranteed

Discover Patagonia's splendor by biking the high fields of 25 de Mayo Nature Reserve. After a 4x4 climb towards Calafate stream valley, pedal 10 miles with our expert guide unveiling spectacular landscapes, unique wildlife, and Tehuelche ruins. Cross the Guanaco Valley before refueling with a well-deserved lunch back at the estancia!

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

El Calafate

Duration1 day

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Quito And Legend Galapagos Cruise - April 2026

Trip customizable

Best price guaranteed

This journey will take you through the ancient splendors of Quito and the exotic islands of the Galapagos with their endemic animals. Begin your journey in Quito, the breathtaking capital city surrounded by the Andes Mountains. From there you will catch your flight to Baltra Island and sail to Santa Cruz, where you will learn about the volcanic soils and search for the world- famous Giant Tortoises. Next, you will travel to incredible places as Genovesa Island and Darwin Bay, where you will have the chance to see the Red-footed Boobies, as well as experience on sand, rock and lava formations so common in this area. Your next destinations will be Plaza Island and Santa Fe Island, where you will be immediately distracted by the abundant sea lions. On different stops you will have the chance to spot different variety of birds, such as Blue Footed Boobies, Frigate Birds, Red- Billed Tropicbirds, Swallow-Tailed Gulls. You will also have the opportunity to snorkel in turquoise waters and wonder at Galapagos amazing aquatic life. End you exploration the by Bachas Beach and visit the lagoon with wading birds, marine iguanas and sometimes even flamingoes. Finally fly back to Quito to connect with your flight back home.

CruiseWildlife

Tour Type

Cruise Tour

Accommodation

Ship Cabin, Hotel

Age Range

8-99 yrs

Operated in

english

Destinations

Quito, Galapagos Islands, Darwin

Quito, Galapagos Islands, Darwin Bay, Santa Fe Island, Baltra Island

Duration6 days

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Perito Moreno Kayak Experience - April 2026

Trip customizable

Best price guaranteed

Live a unique experience! Our excursion gives you the chance to discover the Perito Moreno Glacier, declared a World Natural Heritage Site, from a totally different perspective: through a kayaking adventure

Kayaking and canoeing

Tour Type

Small Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

El Calafate, Patagonia

Duration1 day

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Half Day Orongo and Rano Kau on Easter Island - April 2026

Trip customizable

Best price guaranteed

Discover the fascinating history and culture of Rapa Nui on this half-day tour. Explore the archaeological site of Vinapu. Visit the ceremonial village of Orongo. Finish with panoramic views from the Rano Kau volcano viewpoint. A journey filled with history, culture, and unforgettable landscapes!

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Easter Island

Duration1 day

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Rafting on the Petrohue River Rapids - April 2026

Trip customizable

Best price guaranteed

Embark on an exciting rafting adventure on the Petrohué River, surrounded by majestic volcanoes. Enjoy 1h30 of adrenaline and fun in class III and IV rapids, with stops to swim and jump from cliffs. Equipped with wetsuits and guided by experts, this experience promises to be unforgettable. Ideal for families and adventurers, come and experience the magic of Rafting on the Petrohué River!

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Puerto Varas

Duration1 day

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Pablo Escobar Escape Route Tour - April 2026

Trip customizable

Best price guaranteed

Learn about Pablo Escobar’s life, his drug empire and how Colombia was able to finally get rid of the notorious drug lord. Pablo Escobar escape route tour is a four-hour trip that starts and ends in Medellin. The tour takes you to witness the famous La Catedral—Escobar’s luxurious private prison he built for himself to avoid being extradited to the United States. Immerse in the history of Pablo Escobar’s drug reign in Colombia as you walk through the escape route used by Pablo and his crew to flee his private prison in 1993. This fully narrated tour with an experience local guide will lead you through natural sceneries and spectacular views away from the bustling city.

Sightseeing ToursWalking tours

Tour Type

Private Tour

Age Range

1-99 yrs

Operated in

english, spanish

Destinations

Medellin

Duration4 hours

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Rio Mendoza Rafting - April 2026

Trip customizable

Best price guaranteed

In Mendoza, there are many different ways to experience the snowmelt waters of the Andes. For the adventurer, we offer rafting trips throughout the year on a Class III river. All of our excursions are on the wild and scenic portion of the Mendoza River, above the Potrerillos Dam and Reservoir

Rafting

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

10-60 yrs

Operated in

english

Destinations

Mendoza

Duration1 day

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Half-Day Canopy Zipline Adventure - April 2026

Trip customizable

Best price guaranteed

It is an amazing and fun journey through the forest. To share with the family, enjoying the mountains and experiencing the unforgettable sensation of flying, after the transfer from your hotel, we reached the base Cerro López where we can find the refuge bar, there, you will receive an instructive talk and we will give you the first line equipment the. Then, the ascent in vehicles is carried out to the highest platform and from there begin flight 1500 meters distributed over 10 platforms. During the descent you can enjoy panoramic views

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Neuquen

Duration1 day

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Premium Cafayate Wine Route - April 2026

Trip customizable

Best price guaranteed

The excursion is a tour by two wineries of Cafayate that are positioned as ones of the best of the Calchaqui Valley. These could be San Pedro de Yacochuya & Piattelli Vineyards on the west and El Esteco & El Porvenir de los Andes on the east. The tour could not be complete if we do not visit the Museum of the Vine and Wine. In each winery we do a tour by the facilities and a tasting of the best wine produced in the winery. The tour and the tasting are guided by a sommelier that explains the particularities of the wine, the vine and cellar as well

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Cafayate

Duration1 day

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All South America Tours in April 2026

Page 61 of 1,405 Trips in South America during April 2026 with 3,670 Reviews

Essential Colombia to Chile - 21 days - April 2026

Real Bolivia to Brazil - April 2026

Rafting in Mendoza - April 2026

Central America Youth Expedition - 40 days - April 2026

Machu Picchu & Galapagos - April 2026

Patagonia Bike Safari: Wilderness & Wildlife - April 2026

Quito And Legend Galapagos Cruise - April 2026

Perito Moreno Kayak Experience - April 2026

Half Day Orongo and Rano Kau on Easter Island - April 2026

Rafting on the Petrohue River Rapids - April 2026

Pablo Escobar Escape Route Tour - April 2026

Rio Mendoza Rafting - April 2026

Half-Day Canopy Zipline Adventure - April 2026

Premium Cafayate Wine Route - April 2026

Page 61 of 1,405 Trips in South America during April 2026 with 3,670 Reviews

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All South America Tours in April 2026

Page 61 of 1,405 Trips in South America during April 2026 with 3,670 Reviews

Page 61 of 1,405 Trips in South America during April 2026 with 3,670 Reviews