12-Day South America Tours - Unique 12-Day tours to South America

Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

Buenos Aires, Uruguay and Asunción Exploration - 12 days

Trip customizable

Best price guaranteed

Trace the pulse of South America on this vivid Buenos Aires, Uruguay and Asunción Exploration. Designed with young adults and experienced travelers in mind, this 12-day tour weaves through Montevideo’s historic heart, the rolling vineyards of Canelones, and the UNESCO-listed streets of Colonia del Sacramento. Savor Uruguay’s Tannat wine, experience Buenos Aires’s tango scene, and venture into Argentina’s Pampas for a taste of gaucho tradition. The journey concludes in Paraguay’s capital, Asunción, where colonial charm and bustling markets await. The USP: an expertly guided adventure blending vibrant urban culture, regional cuisine, and historical depth across three captivating nations.

City sightseeing

Tour Type

Private Tour

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Montevideo, Coloni

Buenos Aires, Montevideo, Colonia Del Sacramento, Asuncion, Colonia

Duration12 days

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The Argentine North in - 12 days

No booking fees

Best price guaranteed

Set your sights on Argentina’s northern wonders with "The Argentine North in 12 Days"—a guided tour crafted for those eager to experience the vibrant heart of the country’s landscapes and culture. Beginning in Buenos Aires, this journey whisks you away to Mendoza, where world-renowned malbec wines await, and onward to Salta, a region celebrated for its dramatic scenery and historical landmarks such as the stunning Humahuaca Canyon. The adventure culminates at the awe-inspiring Iguazu Falls, one of South America’s most spectacular natural landmarks, straddling the border between Argentina and Brazil. Here, you’ll spend three nights exploring both the Argentine and Brazilian perspectives of the falls, ensuring a complete and unforgettable experience of this UNESCO World Heritage Site. Please note, domestic flights are not included, allowing you flexibility in your travel arrangements. The unique selling point of this tour? A meticulously curated route that packs wine, culture, history, and natural marvels into one seamless trip—perfect for travelers seeking a comprehensive exploration of Argentina’s diverse north.

City sightseeingWaterfalls

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Puerto Iguazu, Igu

Buenos Aires, Puerto Iguazu, Iguazu Falls, Mendoza, Salta

Duration12 days

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Incas, Titicaca & La Paz - 12 days

No booking fees

Best price guaranteed

Set out on a seamless adventure from Lima to La Paz with the Incas, Titicaca & La Paz – 12 Days tour, tailored for experienced travelers and seniors eager for a comprehensive yet easy-paced exploration. Journey through the highlights of Peru—delve into Lima’s vibrant culture, wander the ancient streets of Cusco, and explore the breathtaking Sacred Valley, including Pisac and Ollantaytambo Fortress. Cross into Bolivia to visit the lakeside charm of Copacabana and discover the world’s highest capital, La Paz. The trip’s signature feature is a boat excursion on Lake Titicaca, offering rare access to island communities. This expertly guided tour delivers a perfect blend of historical, cultural, and scenic wonders, all with outstanding comfort and organization.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, Copacabana, Cusco

Lima, La Paz, Copacabana, Cusco, Sacred Valley, Puno

Duration12 days

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North Argentina Highlights - 12 days

No booking fees

Best price guaranteed

Embark on a 12-day exploration of Argentina’s northwest, starting and ending in Buenos Aires. This private cultural tour reveals ochre deserts, snow-dusted peaks, colonial towns, and ancient ruins. Wander through Salta and Cafayate, meet indigenous communities, and marvel at colorful gorges. Crafted for travelers who appreciate variety and authenticity, this trip’s special appeal lies in its journey through Argentina’s most diverse and visually stunning region, all with the comfort of expert guidance and well-appointed accommodations.

Cultural, religious and historic sites

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Buenos Aires, Tafí Del Valle, Sa

Buenos Aires, Tafí Del Valle, Salta, Purmamarca, Cafayate

Duration12 days

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Exploring Ecuador: From the Andes to the Coast - 12 days

Trip customizable

Best price guaranteed

Experience the diverse beauty of Ecuador on a remarkable journey. Start your adventure with a smooth airport transfer to your hotel. Explore Otavalo's bustling market, marvel at the serene Cuicocha Lagoon, and immerse yourself in the craftsmanship of Cotacachi. Discover the heart of Quito on a city tour and venture to the breathtaking Cotopaxi National Park and Quilotoa Lagoon. Relax in the "Baños de Agua Santa" and encounter unique wildlife in the Chimborazo Fauna Production Reserve. Dive into the local culture at the Puruha Community, explore the vibrant Guamote Market, and witness the mystical Ozogoche—a journey through history at the Cañari Culture and Ruins of Ingapirca. Uncover Cuenca's charm on a city tour, visit Gualaceo and Chordeleg, and explore El Cajas National Park and a Cacao Farm. In Guayaquil, take in the city's highlights, then conclude your adventure with a transfer out from the airport to round off your Ecuadorian exploration. See the itinerary section for more details.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-60 yrs

Operated in

english, spanish

Destinations

Quito, Cuenca, Guayaquil, Banos

Quito, Cuenca, Guayaquil, Banos, Cajas National Park, Cotacachi, Quilotoa, Chimborazo, Guamote

Duration12 days

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Andean Adventure: Traversing Ecuador's Icons - 12 days

Trip customizable

Best price guaranteed

Experience the best of Ecuador on an exclusive women's journey, blending cultural immersion with natural wonders. From the vibrant markets of Otavalo to the tranquil Polylepis Lodge, enjoy spa treatments, Amazon adventures, and cultural engagements, immerse yourself in the heart of Ecuador's culture, history and natural beauty. Explore Baños, Quilotoa, and Cotopaxi, and participate in hands-on experiences like cooking classes and rose plantation visits. Connect with like-minded women travelers, savor local flavors, and delve into indigenous traditions. Enjoy nature walks, wildlife encounters, photography sessions at stunning sites and relaxing spa services during this epic all-women Ecuador vacation. See the itinerary section for more details.

Trekking and HikingHot springs

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

18-70 yrs

Operated in

english, spanish

Destinations

Amazon Ecuador, Quito, Cotopaxi

Amazon Ecuador, Quito, Cotopaxi National Park, Amazon Jungle Lodge, Otavalo, Banos

Duration12 days

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South America 12-Day Tours and Trips

Page 2 of The Best 12-day Trips in South America with 81 Reviews