10 Best Santa Cruz Multiday Tours in April 2026

Get a customized trip to Santa Cruz in April 2026

Plan a multi-country or regional adventure across Santa Cruz in April 2026, with help from a local expert.

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Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

Black Friday Super Sales

The Galápagos: Wildlife of Santa Cruz & Isabela Islands - April 2026

(4 reviews )

No booking fees

Best price guaranteed

This was a trip of a lifetime! G adventures and our CEO's, Felipe and Gustavo, made everything so enjoyable and easy! Getting to the Galapagos was no easy feat and our CEO's handled everything with professionalism and enthusiasm. I felt like I was able to show up and not have to think about anything. I will definitely be booking Gluxe adventures again!

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-100 yrs

Operated in

english

Destinations

Quito, Galapagos Islands, Isabel

Quito, Galapagos Islands, Isabela Island, Santa Cruz

Duration8 days

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Quito & Galapagos Explorer (superior) - 5 Days - April 2026

13% OFF TODAY

Black Friday Super Sales

Quito & Galapagos Explorer (Superior) - 5 days - April 2026

No booking fees

Best price guaranteed

Embark on an express tour of the Galapagos island of Santa Cruz, from the Ecuadorean capital of Quito. Spot giant tortoises roaming in the Highlands and snorkel alongside sea lions and turtles. Hike to one of the island's finest viewpoints and set out to sea on a full day boat trip with an ex-fisherman, to take in the incredible marine life and scenery. End your tour back in Quito or Guayaquil, Ecuador's second city.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Quito, Santa Cruz, Galapagos Islands

13% OFF TODAY

Duration5 days

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Black Friday Super Sales

Best of the Galapagos - April 2026

Trip customizable

Best price guaranteed

Embark on an unforgettable journey through Ecuador, starting with a day of acclimatization and exploration in the charming city of Quito. From there, fly to the awe-inspiring Galapagos Islands, where you'll witness the unique biodiversity that inspired Charles Darwin's theory of evolution. Discover the volcanic wonders of Isabela Island, snorkeling through lava tunnels teeming with marine life and kayaking alongside penguins and sea lions. Hike to the second-largest lava dome in the world, Sierra Negra Volcano, and savor a farm-to-table lunch amidst breathtaking scenery. Continue your adventure on Santa Cruz Island, home to the Charles Darwin Research Station and the "Primicias" reserve, where you can observe giant tortoises in their natural habitat. Immerse yourself in the local culture of Puerto Ayora before returning to Quito, where your journey began. Departing with cherished memories and a deeper appreciation for Ecuador's natural wonders, you'll be left yearning to return and explore more of this captivating country. In the Galapagos we offer a selection of tours of varying lengths and activity levels: 7 Day - Galapagos Essentials - Our lead-in product, ideal for those looking to experience the natural beauty of the Galapagos without being too active. This tour visits the Islands of Santa Cruz and San Cristobel. 7 Day - Best of the Galapagos - For those looking for an activity based trip to the Galapagos, our Best of the Galapagos tour has a more active itinerary, including a hike on the Sierra Negra Volcano. This tour visits the Islands of Isabela and Santa Cruz. 10 Day - Galapagos Uncovered - For passengers with more time available, our Galapagos Uncovered tour is a great option, this tour includes a good mix of activities and includes visits to three islands; San Cristobel, Isabela and Santa Cruz.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

8-95 yrs

Operated in

english

Destinations

Quito, Baltra Island, Tintoreras

Quito, Baltra Island, Tintoreras, Santa Cruz

Duration7 days

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Ecuador To Galápagos: Jungle Beats & Island Heat - April 2026

18% OFF TODAY

Black Friday Super Sales

Ecuador to Galápagos: Jungle Beats & Island Heat - April 2026

No booking fees

Best price guaranteed

If wild jungles crystal-clear crater lakes and volcanic island vibes sound like your kind of adventure, Ecuador is about to blow your mind. This 17-day trip kicks off deep in the Amazon where you’ll wake up to monkey calls and fall asleep to jungle symphonies. Pedal through local communities eat your weight in handmade chocolate and soak in the thermal energy of Baños. Then it’s off to Quilotoa — a dreamy turquoise crater lake you’ll hike down to and maybe even kayak across. Just when you think the trip couldn’t get any better you’ll head to the legendary Galápagos Islands for epic snorkelling, volcanic hikes, and more wildlife than your camera roll can handle. This is Ecuador turned all the way up.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

18-39 yrs

Operated in

english

Destinations

Quito, Santa Cruz, Isabela Islan

Quito, Santa Cruz, Isabela Island, San Cristobal Island, Tena, Banos, Quilotoa

18% OFF TODAY

Duration17 days

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Quito & Galapagos Explorer - 5 Days - April 2026

13% OFF TODAY

Black Friday Super Sales

Quito & Galapagos Explorer - 5 days - April 2026

No booking fees

Best price guaranteed

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Quito, Santa Cruz, Galapagos Islands

13% OFF TODAY

Duration5 days

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Santa Cruz Tours in April 2026

Get a customized trip to Santa Cruz in April 2026

5 Trips in Santa Cruz during April 2026

The Galápagos: Wildlife of Santa Cruz & Isabela Islands - April 2026

Quito & Galapagos Explorer (Superior) - 5 days - April 2026

Best of the Galapagos - April 2026

Ecuador to Galápagos: Jungle Beats & Island Heat - April 2026

Quito & Galapagos Explorer - 5 days - April 2026

5 Trips in Santa Cruz during April 2026

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Food, wine, events and nightlife

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Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

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Santa Cruz Tours in April 2026

Get a customized trip to Santa Cruz in April 2026

5 Trips in Santa Cruz during April 2026

The Galápagos: Wildlife of Santa Cruz & Isabela Islands - April 2026

Quito & Galapagos Explorer (Superior) - 5 days - April 2026

Best of the Galapagos - April 2026

Ecuador to Galápagos: Jungle Beats & Island Heat - April 2026

Quito & Galapagos Explorer - 5 days - April 2026

5 Trips in Santa Cruz during April 2026