10 Best Mexico and Panama Tours and Trip Packages 2025/2026 (with 90+ reviews)

Panama City to Mexico Maya Express Pass

No booking fees

Best price guaranteed

Embark on an unforgettable adventure with Bamba's Panama City to Mexico Maya Express Pass! Traverse vibrant Central America, exploring lush rainforests, pristine beaches, and ancient Mayan ruins. Indulge in rich cultural experiences and exhilarating activities like zip-lining, snorkeling, and more. Perfect for thrill-seekers and culture enthusiasts, this tour promises breathtaking scenery and unforgettable memories. Discover hidden gems, savor local cuisines, and immerse yourself in diverse traditions on this captivating journey from Panama to Mexico.

Active and outdoor

Tour Type

Group Tour

Accommodation

Hostel, Home-stay, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, Cancún, San Blas Is

Panama City, Cancún, San Blas Islands, San Jose, Monteverde Cloud Forest Biological Preserve, San Juan Del Sur, Granada, Leon, El Tunco, Antigua, Panajachel, San Jorge La Laguna, Lanquin, Flores, Belize City, Caye Caulker, Chetumal, Tulum, Playa Del Carmen, Bocas Del Toro, Puerto Viejo de Talamanca, Tortuguero National Park

Duration40 days

From

USD 3,654

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13% OFF TODAY

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Best of Central America

No booking fees

Best price guaranteed

Explore incredible worlds above and below the water through some of Central America's best on this 45-day adventure. Amble down the Yucatan Peninsula to the island paradise of Caye Caulker, then cut inland to the lush jungle around Tikal, cruise to the wide river Rio Dulce and end up among the clouds in Panajachel and Antigua. Continue to the relaxing beach vibes of the Pacific Coast of El Salvador, spot colourful birds perched on the historic facades of Suchitoto and explore the historic cities of Leon and Granada in Nicaragua. Stand in the shadow of mighty Arenal Volcano and spot sloths among the canopy of Monteverde, then admire the towns and steamy jungles of Costa Rice and Panama, stopping off at the stunning islands of Bocas del Toro. With plenty of moments to meet the locals and try the region’s varied cuisines, you can’t go wrong on this carefree Central American journey.

WildlifeCity sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Panama City, Playa Del Carmen, R

Panama City, Playa Del Carmen, Rio Dulce, Antigua, Quetzaltenango, Panajachel, Tulum, Copan, Suchitoto, La Libertad, Leon, Granada, Monteverde, La Fortuna, San Jose, Sarapiqui, Puerto Viejo de Talamanca, Bocas Del Toro, Caye Caulker, Boquete, Chitre, San Ignacio, Flores

13% OFF TODAY

Duration45 days

From

USD 7,390

USD 6,451

Saving

USD 939

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13% OFF TODAY

Super Sales

Ultimate Central America

No booking fees

Best price guaranteed

Embark on an in-depth, 59-day Central American adventure from Mexico’s capital to the home of the Panama Canal. Pass through Mexico, Belize, Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica and Panama on a small-group journey through remote villages, historic cities, ancient Maya and Aztec ruins, verdant cloud forests and pure Caribbean beaches. Get acquainted with the local cultures, spectacular landscapes and fascinating histories of Central America as you explore the wealth of tradition, spot the range of unusual wildlife, dive into unique underwater worlds and spend time travelling with like-minded people. Did you hear that? Central America is calling – you better Belize it.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Mexico City, Panama City, Palenq

Mexico City, Panama City, Palenque, Merida, Playa Del Carmen, Chetumal, Caye Caulker, San Ignacio, Flores, Rio Dulce, Antigua, Quetzaltenango, Puebla, Panajachel, Copan, Suchitoto, La Libertad, Leon, Granada, Monteverde, La Fortuna, San Jose, Sarapiqui, Oaxaca, Puerto Viejo de Talamanca, Bocas Del Toro, Boquete, Chitre, San Cristobal De Las Casas

13% OFF TODAY

Duration59 days

From

USD 10,390

USD 9,070

Saving

USD 1,320

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Cancun to Panama City Travel Pass

No booking fees

Best price guaranteed

Embark on an unforgettable Central American adventure, exploring pristine beaches, vibrant cities, and lush jungles. This travel pass takes you from Cancun to Panama City, offering immersive experiences like snorkeling in Belize’s Blue Hole, discovering Mayan ruins in Guatemala, and hiking Costa Rica’s volcanoes. Enjoy local cultures, authentic cuisines, and breathtaking landscapes. Perfect for thrill-seekers and culture enthusiasts, this journey provides incredible opportunities to make lasting memories while venturing through this diverse and captivating region.

Active and outdoor

Tour Type

Group Tour

Accommodation

Hostel, Home-stay, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, Cancún, Belize City

Panama City, Cancún, Belize City, Flores, Rio Dulce, Lanquin, Panajachel, San Jorge La Laguna, Playa Del Carmen, Antigua, Copán Ruinas, El Tunco, Leon, Granada, San Jorge, San Juan Del Sur, Monteverde Cloud Forest Biological Preserve, Manuel Antonio National Park, San Jose, Tulum, Tortuguero, Puerto Viejo De Sarapiqui, Bocas Del Toro, San Blas Islands, Bacalar, Chetumal, Caye Caulker

Duration48 days

From

USD 4,231

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Panama City to Cancun Travel Pass

No booking fees

Best price guaranteed

Explore vibrant Panama City and stunning Cancun with Bamba’s unforgettable travel pass. Dive into crystal-clear cenotes, roam ancient Mayan ruins, and relax on pristine beaches. Experience vibrant local culture, indulge in delicious cuisine, and witness breathtaking Caribbean sunsets. Perfect for adventure seekers and culture lovers alike, this journey offers unique experiences and exciting activities at every stop. Make lasting memories on this ultimate Central American escape. Book now for an adventure of a lifetime!

VolcanoesLocal culture

Tour Type

Group Tour

Accommodation

Hostel, Hotel, Home-stay

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, Cancún, San Blas Is

Panama City, Cancún, San Blas Islands, San Jose, Monteverde Cloud Forest Biological Preserve, San Juan Del Sur, Granada, Leon, El Tunco, Copán Ruinas, Antigua, Panajachel, San Jorge La Laguna, Lanquin, Flores, Belize City, Caye Caulker, Chetumal, Bacalar, Tulum, Playa Del Carmen, Bocas Del Toro, Puerto Viejo de Talamanca, Tortuguero National Park

Duration43 days

From

USD 3,800

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Mexico City to Panama City Travel Pass

No booking fees

Best price guaranteed

Discover the ultimate adventure from Mexico City to Panama City with this travel pass, offering a thrilling journey through Central America's cultural and natural wonders. Explore ancient Mayan ruins, lush rainforests, stunning beaches, and vibrant cities. Experience authentic local cuisine, breathtaking landscapes, and diverse wildlife. This adventure guarantees an unforgettable blend of history, nature, and adventure-packed activities, ideal for those seeking to immerse themselves in the rich and varied tapestry of Central America.

Overland Journeys

Tour Type

Group Tour

Accommodation

Home-stay, Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Mexico City, Panama City, Palenq

Mexico City, Panama City, Palenque, Merida, Playa Del Carmen, Tulum, Bacalar, Chetumal, Caye Caulker, Oaxaca, Belize City, Flores, Rio Dulce, Lanquin, Panajachel, San Jorge La Laguna, Antigua, Copán Ruinas, El Tunco, Leon, Granada, San Jorge, San Juan Del Sur, Monteverde Cloud Forest Biological Preserve, Manuel Antonio National Park, San Jose, Puerto Escondido, Puerto Viejo de Talamanca, Bocas Del Toro, San Blas Islands, Pochutla, San Cristobal De Las Casas

Duration57 days

From

USD 4,461

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Panama City to Mexico City Travel Pass

No booking fees

Best price guaranteed

Embark on a vibrant journey from Panama City to Mexico City with Bamba Travel, exploring stunning landscapes, rich cultures, and iconic landmarks. Delight in unique experiences such as traversing the Panama Canal, wandering through colonial Cartagena, adventuring in Costa Rica’s lush rainforests, and diving into the vibrant markets of Oaxaca. Savor authentic Latin American cuisine, immerse in local traditions, and enjoy seamless travel connections. Perfect for thrill-seekers and culture enthusiasts, this adventure promises unforgettable memories.

Local culture

Tour Type

Group Tour

Accommodation

Home-stay, Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Mexico City, Panama City, San Bl

Mexico City, Panama City, San Blas Islands, San Jose, Manuel Antonio, Monteverde, Liberia City, San Juan Del Sur, San Jorge, Ometepe, Granada, Leon, El Tunco, Copán Ruinas, Antigua, Panajachel, San Jorge La Laguna, San Cristobal De Las Casas, Pochutla, Puerto Escondido, Bocas Del Toro, Oaxaca, Puerto Viejo de Talamanca, Tortuguero

Duration42 days

From

USD 4,019

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Total Central America: Two Months Of Wild

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Total Central America: Two Months of Wild

No booking fees

Best price guaranteed

Two months. Seven countries. One unforgettable ride. This all-out Central American adventure kicks off in Mexico City with tacos, mole, and big energy — then it’s full speed ahead through mountains, jungles, highlands, beaches, and islands. You’ll snorkel in Belize, boat across Lake Atitlán, crash with a local fam on Nicaragua’s Ometepe Island, and dance the night away in Panama City. Whether you’re soaking in cloud forest vibes in Costa Rica or chilling barefoot on the San Blas Islands, this trip is the ultimate way to see it all. From street eats to off-the-grid retreats, it’s two months of pure adventure — and it’s calling your name.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Home-stay, Hostel, Hotel, Hut

Age Range

18-39 yrs

Operated in

english

Destinations

Mexico City, Panama City, Bacala

Mexico City, Panama City, Bacalar, Valladolid, Tulum, Playa Del Carmen, Caye Caulker, San Ignacio, Flores, Rio Dulce, Antigua, Panajachel, San Juan La Laguna, Oaxaca, Copan, Suchitoto, La Libertad, Leon, Granada, Isla De Ometepe, Monteverde, La Fortuna, San Jose, Puerto Viejo de Talamanca, Bocas Del Toro, San Cristobal De Las Casas, Boquete, Valle De Antón, San Blas Islands, Palenque

13% OFF TODAY

Duration62 days

From

USD 6,199

USD 5,412

Saving

USD 787

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All Mexico and Panama Tours and Trips

8 Trips in Mexico and Panama

8 Trips in Mexico and Panama

Panama City to Mexico Maya Express Pass

Best of Central America

Ultimate Central America

Cancun to Panama City Travel Pass

Panama City to Cancun Travel Pass

Mexico City to Panama City Travel Pass

Panama City to Mexico City Travel Pass

Total Central America: Two Months of Wild

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Mexico and Panama Tours and Trips

8 Trips in Mexico and Panama

8 Trips in Mexico and Panama