10 Best Mendoza Multiday Tours in October 2025

Get a customized trip to Mendoza in October 2025

Plan a multi-country or regional adventure across Mendoza in October 2025, with help from a local expert.

Maria SzlafszteinTravel Expert in Argentina, Bolivia, Brazil, Chile, Ecuador, Paraguay, Peru & Uruguay
Clara GonzalezTravel Expert in Argentina, Bolivia, Brazil, Chile, Ecuador, Paraguay, Peru & Uruguay
Ezequiel Fernandez Estelrich
Travel Expert in Argentina & Chile
Axel Bulgheroni
Travel Expert in Argentina & Chile
Oxana ProtchenkoTravel Expert in Argentina & Chile
Christian MorrisonTravel Expert in Argentina & Chile

Start planning your Trip

Recommended by

Discovering the Best of Argentina - October 2025

(16 reviews )

Trip customizable

Best price guaranteed

I had an outstanding experience working with the travel team for my trip to Argentina. From the very beginning, their team was professional, responsive, and incredibly knowledgeable about the best destinations and experiences. They tailored the itinerary perfectly to my preferences, ensuring a seamless and stress-free journey. Every detail, from accommodations to excursions, was well thought out, and their local expertise truly made a difference. I especially appreciated their prompt communication and willingness to accommodate any requests. Thanks to the team, my trip was not only memorable but also hassle-free. I highly recommend them to anyone looking for a well-organized and authentic travel experience in Argentina!

City sightseeingNational parks

Tour Type

Private Tour

Accommodation

Hotel, Resort, Tent

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, El C

Buenos Aires, Iguazu Falls, El Calafate, Ushuaia, Perito Moreno Glacier, Mendoza

Duration15 days

From

USD 4,005

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Tango, Wine & Blue water dreams - October 2025

(13 reviews )

Trip customizable

Best price guaranteed

Nearly all of the guides were wonderful. I don’t remember the name of the guide who took us to El Chaltén but we appreciated that he took us seriously as trekkers and suggested a slightly longer trek with beautiful views. We thoroughly enjoyed that trek! And we also were very happy with our guide in Tiera del Fuego. She was very lively, knowledgeable and provided us with a couple of wonderful hike and a delicious lunch. We loved all she knew about the birds, trees and geology on the area."

City sightseeing

Tour Type

Private Tour

Accommodation

Hotel, Resort

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, Mend

Buenos Aires, Iguazu Falls, Mendoza, Patagonia, San Carlos de Bariloche

Duration12 days

From

USD 3,695

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Santiago to Rio de Janeiro Travel Pass - October 2025

No booking fees

Best price guaranteed

Discover South America's majestic wonders on an unforgettable adventure from Santiago to Rio de Janeiro. Experience the thrill of hiking in Chile's picturesque landscapes, exploring Buenos Aires' vibrant culture, and soaking in Iguazu Falls' breathtaking views. With immersive local activities, cultural encounters, and scenic routes, this tour offers a perfect blend of nature and urban excitement. Ideal for travelers eager to uncover hidden gems, this journey promises an enriching and exhilarating exploration of diverse cultures and stunning scenery. Embark on the ultimate South American expedition today!

Local boat rides

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Puerto

Santiago, Rio de Janeiro, Puerto Iguazu, Florianopolis, Sao Paulo, Paraty, Mendoza, Ilha Grande, Córdoba, Buenos Aires

Duration25 days

From

USD 1,723

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Rio de Janeiro to Santiago Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Rio de Janeiro to Santiago, exploring South America’s vibrant culture and breathtaking landscapes. Dive into lively Rio’s beaches, marvel at Iguazu Falls’ natural wonders, and revel in Buenos Aires’ rich history. Experience Chile’s scenic beauty in Colchagua Valley and the energetic atmosphere of Santiago. Perfect for thrill-seekers and cultural enthusiasts, enjoy unique excursions including wine tasting and tango dancing lessons. Discover the essence of South America with this curated travel experience.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Floria

Santiago, Rio de Janeiro, Florianopolis, Foz Do Iguacu, Puerto Iguazu, Buenos Aires, Córdoba, Mendoza, Ilha Grande, Paraty, Sao Paulo

Duration21 days

From

USD 1,779

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The Argentine North in 12 Days - October 2025

No booking fees

Best price guaranteed

Join us on this unique 12-day, guided tour to see the best of the Argentine North. Starting from Buenos Aires, Argentina's capital city, this tour will take you to Mendoza, which is known for its famous malbec wine, and Salta, home to stunning landscapes and landmarks like the Humahuaca Canyon. From there you will head for the final destination of the trip, the mighty Iguazu Falls, a South American natural landmark that straddles two countries and draws countless visitors from all over the world each year. Spend three nights in Iguazu and enjoy the beauty of the waterfall from both the Argentinian and the Brazilian side before it's time to head home. Please note that domestic flight tickets are not included in the tour price. For more details, please go through the itinerary below.

City sightseeingWaterfalls

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Puerto Iguazu, Igu

Buenos Aires, Puerto Iguazu, Iguazu Falls, Mendoza, Salta

Duration12 days

From

USD 2,090

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13-Day South America: Mountains & Beaches - October 2025

Trip customizable

Best price guaranteed

This 13-day / 12-night travel package takes you to tour the most impressive cities in South America. We begin in the Argentine capital, Buenos Aires, also known as the "Paris of Latin America" and then continue our journey to Chile, with a halfway stop in Mendoza, a famous wine region. The next city on the itinerary is Santiago de Chile, one of the largest and most sophisticated cities in the country. The last stop will be in Rio de Janeiro, Brazil, a city that offers a perfect combination of culture, nightlife, beaches and natural scenery

MountainsBeachCity sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Resort

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Gu

Buenos Aires, Rio de Janeiro, Guanabara Bay, Mendoza, Santiago, Valparaiso

Duration13 days

From

USD 6,225

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Lima to Buenos Aires (via Chile) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on a captivating South American adventure traversing the vibrant landscapes of Lima, Santiago, and Buenos Aires. This immersive journey takes you through Peru, Chile, and Argentina, offering unique experiences such as exploring the Sacred Valley, witnessing the surreal beauty of the Atacama Desert, and savoring world-renowned Chilean wines. Discover the rich cultural heritage of each city, from Lima's historic center to Buenos Aires' tango-filled streets. Ideal for adventurers and culture enthusiasts seeking an unforgettable travel experience.

City sightseeingLocal culture

Tour Type

Group Tour

Accommodation

Hostel, Hut, Home-stay, Bungalow, Hotel, Lodge, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Lima, Arequipa, Cu

Buenos Aires, Lima, Arequipa, Cusco, Luquina, Puno, Copacabana, Paracas, La Paz, Sucre, Potosi, Uyuni, Candelaria, Polques, San Pedro De Atacama, Calama, Valparaiso, Santiago, Mendoza, Córdoba, Huacachina, Colca Canyon

Duration41 days

From

USD 2,771

View Tour

All Mendoza Tours in October 2025

7 Trips in Mendoza during October 2025 with 29 Reviews

Get a customized trip to Mendoza in October 2025

7 Trips in Mendoza during October 2025 with 29 Reviews

Discovering the Best of Argentina - October 2025

Tango, Wine & Blue water dreams - October 2025

Santiago to Rio de Janeiro Travel Pass - October 2025

Rio de Janeiro to Santiago Travel Pass - October 2025

The Argentine North in 12 Days - October 2025

13-Day South America: Mountains & Beaches - October 2025

Lima to Buenos Aires (via Chile) Travel Pass - October 2025

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Mendoza Tours in October 2025

7 Trips in Mendoza during October 2025 with 29 Reviews

Get a customized trip to Mendoza in October 2025

7 Trips in Mendoza during October 2025 with 29 Reviews

Discovering the Best of Argentina - October 2025

Tango, Wine & Blue water dreams - October 2025

Santiago to Rio de Janeiro Travel Pass - October 2025

Rio de Janeiro to Santiago Travel Pass - October 2025

The Argentine North in 12 Days - October 2025

13-Day South America: Mountains & Beaches - October 2025

Lima to Buenos Aires (via Chile) Travel Pass - October 2025