10 Best Andes Multiday Tours in September 2025

Atacama & Uyuni Salt Flats Adventure 7D/6N - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure through the breathtaking landscapes of the Atacama Desert and Uyuni Salt Flats. Discover awe-inspiring sights like Moon Valley, the striking Red Lagoon, and the world-renowned Uyuni Salt Flats. Experience unique activities such as stargazing in one of the clearest night skies on Earth and exploring surreal rock formations. This tour promises an immersive journey filled with natural wonders, perfect for travelers seeking extraordinary experiences in South America's most dramatic desert scenery.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Uyuni, Calama, San Pedro De Atac

Uyuni, Calama, San Pedro De Atacama, Villamar Mallcu

Duration7 days

From

USD 1,179

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Bolivia Explorer 8D/7N - September 2025

No booking fees

Best price guaranteed

Discover Bolivia's breathtaking landscapes and rich cultural heritage on this immersive adventure. Trek through awe-inspiring Andean mountains, marvel at the otherworldly Uyuni Salt Flats, explore the vibrant streets of La Paz, and uncover ancient ruins in Tiwanaku. This journey offers a perfect blend of nature, history, and local experiences, ensuring unforgettable memories. Ideal for nature enthusiasts and history buffs, this comprehensive tour highlights the must-see destinations and hidden gems of Bolivia. Experience the magic of Bolivia like never before!

AdventureWildlifeWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, La Paz, Isla Del Sol, Uy

La Paz, La Paz, Isla Del Sol, Uyuni, Atulcha, Huayllajara

Duration8 days

From

USD 1,241

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Salta to La Paz Travel Pass - September 2025

No booking fees

Best price guaranteed

Discover the stunning landscapes between Salta and La Paz with an adventure-packed travel pass. Immerse yourself in the vibrant cultures of Argentina and Bolivia while exploring UNESCO World Heritage sites, such as the Quebrada de Humahuaca. Wander through La Paz's bustling street markets, marvel at the breathtaking Salt Flats of Uyuni, and hike in the scenic Andes. Perfect for thrill-seekers and nature enthusiasts, this journey promises unforgettable experiences and unparalleled beauty. Get ready for the adventure of a lifetime!

Active and outdoor

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Salta, Sucre, San Pedro

La Paz, Salta, Sucre, San Pedro De Atacama, Uyuni Salt Flat, Potosi

Duration12 days

From

USD 1,008

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La Paz to Salta Travel Pass - September 2025

No booking fees

Best price guaranteed

Discover the adventure of a lifetime with an exhilarating journey from La Paz to Salta. Embark on vibrant city tours, breathtaking Uyuni Salt Flats excursions, and immersive cultural experiences. Traverse stunning landscapes from Bolivia’s Altiplano to Argentina’s rugged mountains. Enjoy thrilling activities like stargazing, historical site visits, and vibrant local markets. Perfect for adventure seekers and culture enthusiasts, this South American odyssey offers unforgettable memories and unparalleled natural beauty. Join this epic journey and explore some of South America's most iconic destinations!

Sightseeing Tours

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Salta, Candelaria, Lagun

La Paz, Salta, Candelaria, Laguna Colorada, San Pedro De Atacama

Duration9 days

From

USD 906

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Bolivia Highlights Adventure 14D/13N - September 2025

No booking fees

Best price guaranteed

Explore Bolivia like never before with an unforgettable adventure through its most breathtaking landscapes and cultural wonders. Experience the vibrant city of La Paz, marvel at the surreal Uyuni Salt Flats, journey through the heart of the Amazon rainforest, and discover the rich history of Potosi and Sucre. Immerse yourself in local traditions, witness stunning Andean vistas, and embrace thrilling activities like trekking and wildlife spotting. Embrace the ultimate Bolivian escapade filled with unique experiences and unforgettable memories.

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, La Paz, San Juan, Huayll

La Paz, La Paz, San Juan, Huayllajara, Copacabana, Isla Del Sol

Duration14 days

From

USD 1,686

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Santiago to Rio de Janeiro Travel Pass - September 2025

No booking fees

Best price guaranteed

Discover South America's majestic wonders on an unforgettable adventure from Santiago to Rio de Janeiro. Experience the thrill of hiking in Chile's picturesque landscapes, exploring Buenos Aires' vibrant culture, and soaking in Iguazu Falls' breathtaking views. With immersive local activities, cultural encounters, and scenic routes, this tour offers a perfect blend of nature and urban excitement. Ideal for travelers eager to uncover hidden gems, this journey promises an enriching and exhilarating exploration of diverse cultures and stunning scenery. Embark on the ultimate South American expedition today!

Local boat rides

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Puerto

Santiago, Rio de Janeiro, Puerto Iguazu, Florianopolis, Sao Paulo, Paraty, Mendoza, Ilha Grande, Córdoba, Buenos Aires

Duration25 days

From

USD 1,723

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Panama City to Bogota Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Panama City to Bogota, immersing yourself in vibrant cultures, lush landscapes, and rich histories. This seamless travel pass offers unique experiences, including exploring Panama Canal’s marvels, snorkeling in San Blas Islands’ crystal waters, discovering Medellín's urban transformation, and delving into Bogota’s dynamic arts scene. Perfect for thrill-seekers and culture enthusiasts, this tour promises a diverse blend of activities, ensuring an enriching journey through Central America's hidden gems and Colombia's enchanting urban hubs.

BeachSnorkelingExplorer

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Bogota, Panama City, San Blas Is

Bogota, Panama City, San Blas Islands, Medellin, Manizales, Hacienda Venecia Coffe Farm

Duration10 days

From

USD 1,629

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Rio de Janeiro to Santiago Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Rio de Janeiro to Santiago, exploring South America’s vibrant culture and breathtaking landscapes. Dive into lively Rio’s beaches, marvel at Iguazu Falls’ natural wonders, and revel in Buenos Aires’ rich history. Experience Chile’s scenic beauty in Colchagua Valley and the energetic atmosphere of Santiago. Perfect for thrill-seekers and cultural enthusiasts, enjoy unique excursions including wine tasting and tango dancing lessons. Discover the essence of South America with this curated travel experience.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Floria

Santiago, Rio de Janeiro, Florianopolis, Foz Do Iguacu, Puerto Iguazu, Buenos Aires, Córdoba, Mendoza, Ilha Grande, Paraty, Sao Paulo

Duration21 days

From

USD 1,779

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Santiago to La Paz Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Santiago to La Paz, exploring the heart of South America with Bamba Travel. Discover Chile’s vibrant culture and breathtaking landscapes, marvel at Bolivia's otherworldly salt flats, and journey through the Andes. This curated travel experience includes guided tours, vibrant city explorations, and thrilling excursions like Atacama Desert and Uyuni Salt Flats. Perfect for intrepid travelers seeking immersive cultural adventures and natural wonders. Book your South American escapade today for an unforgettable journey!

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, La Paz, Uyuni, Potosi

Santiago, La Paz, Uyuni, Potosi, Sucre, Valparaiso, La Serena, San Pedro De Atacama, Uyuni Salt Flat

Duration17 days

From

USD 1,164

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La Paz to Santiago Travel Pass - September 2025

No booking fees

Best price guaranteed

Discover an unforgettable adventure from La Paz to Santiago, exploring the heart of South America with unparalleled experiences. Traverse Bolivia, Peru, and Chile, diving into the vibrant cultures of each destination. This travel pass immerses you in unique activities like gazing at the Uyuni Salt Flats, exploring the Atacama Desert, and vibrant city vibes. Perfect for backpackers and culture enthusiasts seeking an authentic journey, this tour promises unforgettable memories and breathtaking landscapes. Book now for an epic South American odyssey!

Active and outdoorVolcanoes

Tour Type

Group Tour

Accommodation

Hotel, Hostel, Lodge, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, La Paz, San Pedro De A

Santiago, La Paz, San Pedro De Atacama, La Serena, Valparaiso, Sucre, Potosi, Uyuni, Agencha, Polques

Duration17 days

From

USD 1,257

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Santiago to Ushuaia (Ruta 40) Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Patagonia adventure with Bamba’s epic journey from Santiago to Ushuaia. Traverse the legendary Ruta 40, experiencing breathtaking landscapes, majestic glaciers, and lush national parks. Hike in Torres del Paine, explore the vibrant streets of Buenos Aires, and witness the awe-inspiring Perito Moreno Glacier. This expertly curated tour offers immersive cultural experiences and unparalleled natural beauty, making it perfect for adventurous travelers seeking the ultimate South American expedition. Book now for an extraordinary travel experience.

Active and outdoorAdventure

Tour Type

Group Tour

Accommodation

Hotel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Ushuaia, El Chalten, E

Santiago, Ushuaia, El Chalten, El Calafate, Pucon, Puerto Varas, San Carlos de Bariloche, Perito Moreno Glacier

Duration14 days

From

USD 1,562

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Salta to La Paz Salt Flats Adventure 10D/9N - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from the vibrant culture of Salta to the mesmerizing Uyuni Salt Flats in Bolivia. This 10-day experience offers unique encounters with breathtaking Andean landscapes, ancient ruins, and indigenous villages. Highlights include traversing the awe-inspiring altiplano, marveling at surreal salt deserts, and exploring colorful lagoons teeming with flamingos. Perfect for thrill-seekers and culture enthusiasts, this tour promises an extraordinary blend of nature, history, and adventure for an unmatched South American escape.

AdventureWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Salta, La Paz, San Pedro

La Paz, Salta, La Paz, San Pedro De Atacama, Uyuni

Duration10 days

From

USD 3,440

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Rio de Janeiro to Buenos Aires (via Iguazu) Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from the vibrant streets of Rio de Janeiro to the cultural heart of Buenos Aires, seamlessly connecting you through the awe-inspiring Iguazu Falls. This immersive travel pass offers unique experiences like exploring Brazil's iconic Christ the Redeemer, hiking the lush rainforest, and reveling in Argentina's vibrant tango scene. Perfect for wanderlust-driven explorers, this journey promises unparalleled natural beauty, cultural richness, and thrilling activities, ensuring memories that last a lifetime. Discover South America's best-kept secrets today!

AdventureActive and outdoor

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pu

Buenos Aires, Rio de Janeiro, Puerto Iguazu, Ilha Grande, Paraty, Sao Paulo, Foz Do Iguacu

Duration12 days

From

USD 1,172

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Ushuaia to Santiago (Ruta 40) Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Patagonian adventure from snow-capped Ushuaia to vibrant Santiago along iconic Ruta 40. Discover pristine landscapes, immersive cultural encounters, and thrilling outdoor activities. Highlights include exploring the picturesque Glacier National Park, hiking in stunning El Chaltén, and marveling at the surreal Atacama Desert. Dive into local Argentine and Chilean traditions while indulging in exceptional gastronomy. Experience the ultimate South American journey with diverse terrains, breathtaking vistas, and memorable moments tailored for adventurous travelers.

Active and outdoor

Tour Type

Group Tour

Accommodation

Hotel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Ushuaia, Pucon, El Cal

Santiago, Ushuaia, Pucon, El Calafate, El Chalten, Perito Moreno Glacier, San Carlos de Bariloche, Puerto Varas

Duration12 days

From

USD 1,394

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All Andes Tours in September 2025

176 Trips in Andes during September 2025 with 94 Reviews

176 Trips in Andes during September 2025 with 94 Reviews

Atacama & Uyuni Salt Flats Adventure 7D/6N - September 2025

Bolivia Explorer 8D/7N - September 2025

Salta to La Paz Travel Pass - September 2025

La Paz to Salta Travel Pass - September 2025

Bolivia Highlights Adventure 14D/13N - September 2025

Santiago to Rio de Janeiro Travel Pass - September 2025

Panama City to Bogota Travel Pass - September 2025

Rio de Janeiro to Santiago Travel Pass - September 2025

Santiago to La Paz Travel Pass - September 2025

La Paz to Santiago Travel Pass - September 2025

Santiago to Ushuaia (Ruta 40) Travel Pass - September 2025

Salta to La Paz Salt Flats Adventure 10D/9N - September 2025

Rio de Janeiro to Buenos Aires (via Iguazu) Travel Pass - September 2025

Ushuaia to Santiago (Ruta 40) Travel Pass - September 2025

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Andes Tours in September 2025

176 Trips in Andes during September 2025 with 94 Reviews

176 Trips in Andes during September 2025 with 94 Reviews