10 Best Andes Multiday Tours in October 2025

Rio de Janeiro to Buenos Aires (via Iguazu) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from the vibrant streets of Rio de Janeiro to the cultural heart of Buenos Aires, seamlessly connecting you through the awe-inspiring Iguazu Falls. This immersive travel pass offers unique experiences like exploring Brazil's iconic Christ the Redeemer, hiking the lush rainforest, and reveling in Argentina's vibrant tango scene. Perfect for wanderlust-driven explorers, this journey promises unparalleled natural beauty, cultural richness, and thrilling activities, ensuring memories that last a lifetime. Discover South America's best-kept secrets today!

AdventureActive and outdoor

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pu

Buenos Aires, Rio de Janeiro, Puerto Iguazu, Ilha Grande, Paraty, Sao Paulo, Foz Do Iguacu

Duration12 days

From

USD 1,172

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Santiago to Patagonia - 14 days - October 2025

No booking fees

Best price guaranteed

Discover Chile in all its glorious natural beauty from the glittering lakes of Puerto Varas, the scenic archipelago of Chiloé, the panoramic views from Punta Arenas and the jagged granite peaks of the Paine massif. Along the way visit traditional fishing villages, observe comical penguins and explore Torres del Paine national park in your way.

Sightseeing ToursWaterfalls

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Santiago, Punta Arenas, Torres D

Santiago, Punta Arenas, Torres Del Paine, Puerto Varas, Peulla, Chiloe National Park, Santiago

Duration14 days

From

USD 8,575

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Charming Peru and Colombia - October 2025

Trip customizable

Best price guaranteed

Take a trip to two of the most breathtaking countries in Latin America! With this 13-day small-group tour of Peru and Colombia, you will discover extraordinary attractions, sacred sites, and breathtaking landscapes which are full of history! Begin your tour in Lima, the "City of Kings" famous for its colonial architecture, extraordinary museums, and delicious cuisine. Catch a flight to Cusco and fly over the Andes Mountains, drive through the Urubamba Valley, and explore Machu Picchu, the Lost City of the Incas. Travel through the Sacred Valley of Peru and visit Cusco with a trip to the Santo Domingo Convent. From there you will fly to Bogota, the capital of Colombia and one of the highest capital cities in the world! Visit the Plaza de Bolívar and La Candelaria, two major city highlights, and enjoy the breathtaking views from Montserrate Hill. From there you will travel to the Coffee Triangle to learn about the rich cultural and natural heritage of the region. This is the perfect way to get acquainted with Colombia’s best-known secret — its delicious coffee. End your tour in Cartagena, a breathtaking coastal city in the Caribbean lowlands bordered by magnificent mountains and the Pacific Ocean. Discover the extraordinary lava beaches loved by locals and tourists!

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

8-99 yrs

Operated in

english

Destinations

Lima, Cartagena, Sacred Valley

Lima, Cartagena, Sacred Valley, Armenia, Urubamba, Cusco, Bogota

Duration13 days

From

USD 2,887

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Ushuaia to Santiago (Ruta 40) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Patagonian adventure from snow-capped Ushuaia to vibrant Santiago along iconic Ruta 40. Discover pristine landscapes, immersive cultural encounters, and thrilling outdoor activities. Highlights include exploring the picturesque Glacier National Park, hiking in stunning El Chaltén, and marveling at the surreal Atacama Desert. Dive into local Argentine and Chilean traditions while indulging in exceptional gastronomy. Experience the ultimate South American journey with diverse terrains, breathtaking vistas, and memorable moments tailored for adventurous travelers.

Active and outdoor

Tour Type

Group Tour

Accommodation

Hotel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Ushuaia, Pucon, El Cal

Santiago, Ushuaia, Pucon, El Calafate, El Chalten, Perito Moreno Glacier, San Carlos de Bariloche, Puerto Varas

Duration12 days

From

USD 1,394

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Cartagena To La Paz (58 Days) Bananas & Llamas - October 2025

No booking fees

Best price guaranteed

Take in the unique experiences of South America with this comprehensive, highlight-packed tour. From the biodiversity of Colombia to the fascinating ethnic diversity of La Paz this trip has something for everyone and offers a real taste of all the different facets that South America has to offer. Enjoy the vibrancy of the Caribbean coast before venturing into the highland coffee plantations of Colombia. Spend time in a jungle lodge deep in the Amazon Jungle, enjoy the surf and beautiful beaches of northern Peru, and conquer the world-renowned Inca Trail. Unwind from this adventurous trip with a night with a local Uros Indian family at Lake Titicaca before exploring La Paz, the highest capital city in the world. Please note that the accommodation on this trip is predominantly camping, though there may be opportunities to upgrade this locally where rooms are available. Please see the trip inclusions for an approximate percentage of camping and room nights

Overland Journeys

Tour Type

Group Tour

Accommodation

Lodge, Camping

Age Range

12-85 yrs

Operated in

english

Destinations

La Paz, Cartagena, Tayrona Natio

La Paz, Cartagena, Tayrona National Park, Bogota, Parque Purac, Quito, Amazon Ecuador, Lima, Colca Canyon, Machu Picchu

Duration58 days

From

USD 4,163

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Chile and the Lake District - 14 days - October 2025

No booking fees

Best price guaranteed

Get behind the wheel for this classic self-drive tour of Chile from vibrant Santiago and its neighbouring vineyards to the famed Lake District for outdoor adventure and vistas of pure beauty. Sample world-class wines, admire crystal clear lakes and the backdrop of impressive volcanoes and explore the native rainforest of Huilo Huilo.

Natural landmarks sightseeing

Tour Type

Private Tour

Accommodation

Hotel, Lodge, Resort

Age Range

18-80 yrs

Operated in

english

Destinations

Santiago, Puerto Montt, Puerto V

Santiago, Puerto Montt, Puerto Varas, Santa Cruz, Chillán, Pucon, Huilo Huilo, Santiago

Duration14 days

From

USD 5,205

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Premium Chile & Argentina - October 2025

22% OFF TODAY

Super Sales

Premium Chile & Argentina - October 2025

No booking fees

Best price guaranteed

Against the magnificent backdrop of the Andes Mountains, journey from Santiago to Buenos Aires, taking in all the history, culture and cuisine in between. This nine-day Premium adventure will show you the heart of Chile and Argentina as you stroll the streets of Santiago with a local guide and sip piscos on a rooftop in the historic centre of Valparaiso. Sample some of the world’s best wine in Mendoza, stroll the stylish neighbourhoods of Buenos Aires and discover El Tigre Delta for an adventure to remember. Packed with Exclusive Experiences, historical Feature Stays and with a local leader by your side, you’ll fall for the vibrancy and indulgent atmosphere of this part of the world in no time.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Valparai

Buenos Aires, Santiago, Valparaiso, Mendoza

22% OFF TODAY

Duration9 days

From

USD 6,145

USD 4,769

Saving

USD 1,376

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Buenos Aires, Uruguay and Asunción Exploration - October 2025

Trip customizable

Best price guaranteed

Join us on an unforgettable journey through South America's vibrant cities and scenic landscapes. Begin your 12-day adventure from Montevideo, Uruguay, exploring the city's highlights, including its historic center, Independence Square, and the vibrant Prado neighborhood. Enjoy scenic views from Plaza Virgilio before a delightful dinner and tango show at Primuseum. Next, visit the Canelones wine region for a winery tour and tasting of Uruguay's famed Tannat wine. In Colonia del Sacramento, walk through its Unesco-listed historic district, immersing in its Portuguese heritage. Travel to Buenos Aires, the capital city of Argentina, to experience its dynamic culture, from historic Plaza de Mayo to colorful La Boca and elegant Recoleta. End with an enchanting dinner and tango show. A day in the Pampas reveals gaucho traditions and a traditional Argentine asado. Conclude your trip in Asunción, the capital city of Paraguay, exploring colonial landmarks and vibrant local markets, ensuring a memorable end to your South American adventure.

City sightseeing

Tour Type

Private Tour

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Montevideo, Coloni

Buenos Aires, Montevideo, Colonia Del Sacramento, Asuncion, Colonia

Duration12 days

From

USD 4,810

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14 Day Trip: Galapagos & Machu Picchu - October 2025

Trip customizable

Best price guaranteed

On this 14-day guided tour trip, you will visit the highlights of both Ecuador and Peru. Experience the highlights of the City of Quito, Cotopaxi National Park, the Galapagos Islands: Santa Cruz, El Chato, Charles Darwin Station, Pinzon Island / Isabela Island, Tintoreras, and Cabo Rosa Tunnels. In Peru, you will have the opportunity to get to know the highlights of the ancient Inca civilization. Explore the city of Cusco, the Sacred Valley, the mountain of colors, and Machu Picchu. Visit Inca structures, and learn about the historic Inca settlements and their history. You will be accompanied by a guide, who will assist you with anything you need. We will also provide you with transportation, accommodation and some meals.

Trekking and HikingWildlife

Tour Type

Group Tour

Accommodation

Hotel

Age Range

5-80 yrs

Operated in

english, spanish

Destinations

Cusco, Machu Picchu, Quito, Lima

Cusco, Machu Picchu, Quito, Lima, Galapagos Islands, Santa Cruz, Sacred Valley, Cotopaxi National Park, Mitad Del Mundo, Isla Isabela, Los Túneles

Duration14 days

From

USD 3,995

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Cartagena To Rio (19 Weeks) Kingdoms & Carnivals - October 2025

No booking fees

Best price guaranteed

Explore the very best that this part of the world has to offer with a trip which takes you all the way from densely bio-diverse Colombia all the way to the Brazilian capital. This trip has something for everyone and offers a real taste of all the different facets that South America has to offer. Along the way pay a visit to Ushuaia, the southernmost city in the world, take in the cultural diversity and extremes of climate that spanning 7 countries will inevitably showcase and see both extremes of city immersion and real remoteness. While there will be long drives and tough camping and cooking conditions this tour gives you a unique opportunity to see the real South America and the possibility to meet people you would never otherwise encounter. Our journey ends in Rio, where you will have the chance to join in the world-renowned festivities of Carnival or New Year's Eve celebrations. Please note that the accommodation on this trip is predominantly camping, though there may be opportunities to upgrade this locally where rooms are available. Please see the trip inclusions for an approximate percentage of camping and room nights

Overland Journeys

Tour Type

Group Tour

Accommodation

Camping, Resort, Lodge

Age Range

12-85 yrs

Operated in

english

Destinations

Rio de Janeiro, Cartagena, Tayro

Rio de Janeiro, Cartagena, Tayrona National Park, Uyuni, Salta, Santiago, El Chaltén, Torres del Paine National Park, Ushuaia, Buenos Aires, Iguazu Falls, Bogota, Pantanal, Parque Purac, Quito, Amazon Ecuador, Lima, Colca Canyon, Machu Picchu, La Paz

Duration135 days

From

USD 8,603

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Super Sales

Real Peru to Bolivia - October 2025

No booking fees

Best price guaranteed

With a stay in the heart of the jungle, plenty of pisco sours and some hot and heavy hiking on the Inca Trail, this trip is 15 days of exploring, drinking, eating and sweating (nobody said the trail would be easy, but boy is it worth it). Experience the real Amazon in a proper jungle lodge, follow in the footsteps of ancient people on the Inca Trail to Wonder of the World Machu Picchu and stay with a local family who live in a mud-brick house on the shores of Lake Titicaca. Hit the nightlife in Cusco, sail down the Amazon River in the pitch-black of night (look out for jaguars!) and experience an I’m-so-far-from-home moment with some new friends on an epic trek through Peru to Bolivia.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Lodge, Home-stay

Age Range

18-35 yrs

Operated in

english

Destinations

Lima, La Paz, Puno, Lake Titicac

Lima, La Paz, Puno, Lake Titicaca, La Paz, Puerto Maldonado, Cusco, Ollantaytambo, Inca Trail

Duration15 days

From

USD 2,520

USD 2,444

Saving

USD 76

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Rio de Janeiro to Buenos Aires (via Florianopolis & Iguazu) Travel Pass - October 2025

No booking fees

Best price guaranteed

Discover the ultimate South American adventure with a journey from vibrant Rio de Janeiro to cosmopolitan Buenos Aires, featuring Florianopolis and Iguazu Falls. Experience the iconic beaches of Rio, the nightlife of Florianopolis, and the breathtaking beauty of Iguazu. This travel pass offers thrilling activities like samba shows in Rio, exploring Iguazu's immense waterfalls, and savoring Argentine cuisine in Buenos Aires. Immerse yourself in diverse cultures and stunning landscapes, making unforgettable memories along the way!

City sightseeingWaterfalls

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Fl

Buenos Aires, Rio de Janeiro, Florianopolis, Foz Do Iguacu, Puerto Iguazu, Ilha Grande, Paraty, Sao Paulo

Duration17 days

From

USD 1,288

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13% OFF TODAY

Super Sales

Real Bolivia to Brazil - October 2025

No booking fees

Best price guaranteed

Take an adventure in diverse South America on this 25-day trip from La Paz to Rio de Janeiro. See amazing natural wonders, walk the streets of busy cities and meet the charming locals with a leader by your side who knows all the best spots. Tour the city of Colonia del Sacramento, discover why Salta is nicknamed ‘La Linda’ (‘the beautiful’) and tick immersive Buenos Aires off your bucket list with your new group of friends. Witness the magic of the Iguazu Falls, journey through the untamed desert scenery of San Pedro de Atacama and see the otherworldly Salar de Uyuni salt flats. You’ll have plenty of free time to explore each location, and all the logistics are taken care of for you, so you can concentrate on making new connections and discovering new places.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-35 yrs

Operated in

english

Destinations

Rio de Janeiro, La Paz, Buenos A

Rio de Janeiro, La Paz, Buenos Aires, Montevideo, Estancia, Iguazu Falls, Paraty, Ilha Grande, Salar De Uyuni, Altiplano, San Pedro De Atacama, Salta

13% OFF TODAY

Duration25 days

From

USD 4,735

USD 4,134

Saving

USD 601

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19-Day South America Trip - October 2025

Trip customizable

Best price guaranteed

We will visit the cities of Buenos Aires, El Calafate, Puerto Iguazu, Rio de Janeiro, Lima, Cusco, and Machu Picchu on a 19-day / 18-night journey. Do not miss this opportunity! The Discovering South America travel package includes accommodation, airport transfers, and excursions

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires, Cusco, Rio de Jane

Buenos Aires, Cusco, Rio de Janeiro, Lima, El Calafate, Puerto Iguazu, Iguazu Falls

Duration19 days

From

USD 8,880

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All Andes Tours in October 2025

Page 6 of 1,310 Trips in Andes during October 2025 with 1,562 Reviews

Page 6 of 1,310 Trips in Andes during October 2025 with 1,562 Reviews

Rio de Janeiro to Buenos Aires (via Iguazu) Travel Pass - October 2025

Santiago to Patagonia - 14 days - October 2025

Charming Peru and Colombia - October 2025

Ushuaia to Santiago (Ruta 40) Travel Pass - October 2025

Cartagena To La Paz (58 Days) Bananas & Llamas - October 2025

Chile and the Lake District - 14 days - October 2025

Premium Chile & Argentina - October 2025

Buenos Aires, Uruguay and Asunción Exploration - October 2025

14 Day Trip: Galapagos & Machu Picchu - October 2025

Cartagena To Rio (19 Weeks) Kingdoms & Carnivals - October 2025

Real Peru to Bolivia - October 2025

Rio de Janeiro to Buenos Aires (via Florianopolis & Iguazu) Travel Pass - October 2025

Real Bolivia to Brazil - October 2025

19-Day South America Trip - October 2025

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Andes Tours in October 2025

Page 6 of 1,310 Trips in Andes during October 2025 with 1,562 Reviews

Page 6 of 1,310 Trips in Andes during October 2025 with 1,562 Reviews