10 Best Andes Multiday Tours in October 2025

Best Of Argentina, Uruguay & Brazil - October 2025

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Best of Argentina, Uruguay & Brazil - October 2025

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Hug the eastern coastline of South America on a ten-day adventure. This down-to-earth adventure takes you from Buenos Aires to Rio de Janeiro via Colonia del Sacramento, an estancia and the spectacular Iguazu Falls. Embrace ranch life during your estancia stay and explore the grounds on horseback, wonder at the largest waterfall in the world and get a taste of Rio’s nightlife.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Co

Buenos Aires, Rio de Janeiro, Colonia Del Sacramento, Tacuarembo, Foz Do Iguazu, Iguazu Falls

18% OFF TODAY

Duration10 days

From

USD 2,990

USD 2,465

Saving

USD 525

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Best of Peru And Chile - October 2025

Trip customizable

Best price guaranteed

Head on the adventure of a lifetime with this small-group tour of Peru and Chile! Prepare for a fascinating journey like no other as you discover the most fascinating attractions and ancient sites in Latin America. Begin your tour in Lima, the capital of Peru and the second largest desert capital city in the world. Fly over the snow-capped Andes Mountains to Cusco, travel through the Sacred Valley, take a train to Aguas Calientes, and explore Machu Picchu, the Lost City of the Incas. Make your way back to Cusco where you will visit Santo Domingo Convent and the Sacsayhuaman Fortress. Head on a boat excursion to Lake Titicaca, the highest navigable lake in the world. Catch a flight to Lima and transfer to Santiago, the capital city of Chile surrounded by the Andes Mountains. Discover the Plaza de Armas and Barrio Lastarria before you travel to Puerto Natales and explore Patagonia with its breathtaking mountains, fjords, glaciers, and forests. Your next stop will be in the Atacama Desert — discover the driest desert in the world and explore the Moon Valley, an otherworldly landscape in the Atacama Desert with some of the most stone and sand formations in the world. From there you will travel back to the Atacama to end your tour of Peru and Chile!

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel, Lodge, Villa

Age Range

8-99 yrs

Operated in

english

Destinations

Atacama Desert, Sacred Valley, U

Atacama Desert, Sacred Valley, Urubamba, Santiago, Puerto Natales, San Pedro De Atacama, Cusco, Puno, Lima

Duration17 days

From

USD 4,094

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19-Day Journey through South America - October 2025

Trip customizable

Best price guaranteed

This 19 days / 18 nights travel package offers you to travel the most interesting points of Patagonia, along with Brazil, in the most complete way. Departing from the city of Santiago de Chile, we will make an amazing trip through Patagonia, visiting Puerto Natales, Torres del Paine and El Calafate. Then we continue to the Argentine capital, Buenos Aires, known as the "Paris of Latin America"; The next stop will be in the Iguazú Falls, to finally reach one of Brazil biggest cities: Rio de Janeiro. Do not miss this opportunity!

GlaciersNational parks

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro

Duration19 days

From

USD 10,089

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Explore Peru, Argentina & Brazil - October 2025

13% OFF TODAY

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Explore Peru, Argentina & Brazil - October 2025

No booking fees

Best price guaranteed

South America has many sides, from the energy of the cities and the beauty of the landscape to the spirit of the people. On this 18-day discovery, you’ll wind through the Inca heartlands and jungles of Peru, the enigmatic cities and natural wonders of Argentina and the dynamism of Brazil's vibrant Rio. See animals, meet locals, traverse trails and marvel at all the contrasts of this very special corner of the world. If you’re looking for a trip that hits not one, but two Wonders of the World off your bucket list – you’ve come to the right place. Take a guided tour of Machu Picchu, nestled high in the Andes Mountains, then visit Christ the Redeemer, overlooking breathtaking Rio. Wild ride, anyone?

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay

Age Range

15-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Buenos Air

Rio de Janeiro, Lima, Buenos Aires, Ituzaingo, Foz Do Iguacu, Cusco, Aguas Calientes, Puno, Lake Titicaca

13% OFF TODAY

Duration18 days

From

USD 8,595

USD 7,503

Saving

USD 1,092

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Santiago to Ushuaia (Ruta 40) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Patagonia adventure with Bamba’s epic journey from Santiago to Ushuaia. Traverse the legendary Ruta 40, experiencing breathtaking landscapes, majestic glaciers, and lush national parks. Hike in Torres del Paine, explore the vibrant streets of Buenos Aires, and witness the awe-inspiring Perito Moreno Glacier. This expertly curated tour offers immersive cultural experiences and unparalleled natural beauty, making it perfect for adventurous travelers seeking the ultimate South American expedition. Book now for an extraordinary travel experience.

Active and outdoorAdventure

Tour Type

Group Tour

Accommodation

Hotel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Ushuaia, El Chalten, E

Santiago, Ushuaia, El Chalten, El Calafate, Pucon, Puerto Varas, San Carlos de Bariloche, Perito Moreno Glacier

Duration14 days

From

USD 1,562

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Salta to La Paz Salt Flats Adventure 10D/9N - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from the vibrant culture of Salta to the mesmerizing Uyuni Salt Flats in Bolivia. This 10-day experience offers unique encounters with breathtaking Andean landscapes, ancient ruins, and indigenous villages. Highlights include traversing the awe-inspiring altiplano, marveling at surreal salt deserts, and exploring colorful lagoons teeming with flamingos. Perfect for thrill-seekers and culture enthusiasts, this tour promises an extraordinary blend of nature, history, and adventure for an unmatched South American escape.

AdventureWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Salta, La Paz, San Pedro

La Paz, Salta, La Paz, San Pedro De Atacama, Uyuni

Duration10 days

From

USD 3,440

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Rio de Janeiro & Iguassu Falls Experience - October 2025

Trip customizable

Best price guaranteed

This seven-day group tour is for those interested in seeing some of the most important natural landmarks of Brazil. Start your journey from Rio de Janeiro, also known as "cidade maravilhosa" (the marvelous city), the perfect adjective to describe this city that is home to one of the most famous carnivals in the world, countless natural landscapes, and fun-loving people. See the highlights of the city during a guided sightseeing tour and enjoy the beautiful landscape while hiking the Pedra Bonita trail. *With COVID-19 safety protocols* After that, we’ll head for Foz do Iguacu, commonly referred to as the Iguazu Falls, to see one of the biggest waterfalls in the world from both Brazilian and Argentinian sides. We will drive you to Iguazu Falls airport after the tour is over.

City sightseeingWaterfalls

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english, portuguese, spanish

Destinations

Iguazu Falls, Rio de Janeiro, Fo

Iguazu Falls, Rio de Janeiro, Foz Do Iguacu, Iguazu Falls National Park

Duration7 days

From

USD 2,100

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Mountains to the Lakes - October 2025

Trip customizable

Best price guaranteed

This comprehensive 3 week tour is designed to reveal some of the secrets lying in South America. The tour begins in Lima; you then head south for an incredible Ballestas Islands boat trip where you will see exotic birds and sea mammals. You then travel inland to the desert and the palm trees and sand dunes of the Oasis of Huacachina where we make camp under the stars. You will then visit the mysterious Nazca lines whose true meaning is still up for debate. The tour then starts it's ascent into the Andes to the town of Arequipa and the Colca Canyon, the deepest in the world. The tour then takes us to Cuzco where we prepare for the unforgettable Inca Trail, after reaching Machu Picchu we head back to Cuzco for some relaxing time in this beautiful Andean city. We continue our journey to Lake Titicaca where we spend time learning of the traditions of the local Uros Indians, with free time to laze the day away on the shores of this deep blue lake. The tour makes it's final stop in La Paz, giving you free time to explore the Bolivian capital.

Mountains

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Guest House, Home-stay

Age Range

16-85 yrs

Operated in

english

Destinations

Lima, La Paz, Inca Trail, Machu

Lima, La Paz, Inca Trail, Machu Picchu, Cusco, Puno, Copacabana, Ballestas Islands and Paracas National Reserve, Huacachina, Nazca Lines, Arequipa

Duration21 days

From

USD 4,630

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Best Of Peru Argentina And Brazil - October 2025

4.7

(3 reviews )

Trip customizable

Best price guaranteed

Excellent, saw a lot and have difficulty choosing what was best. Guides, tours and accommodations were great!

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

8-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Sa

Buenos Aires, Rio de Janeiro, Sacred Valley, Lima, Iguazu Falls, Urubamba, Cusco, Puno

Duration14 days

From

USD 3,937

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Machu Picchu and Galapagos - October 2025

4.7

(13 reviews )

No booking fees

Best price guaranteed

Our leader in Peru, Nilton, was excellent , as was Roberto, our leader in Ecuador My only regret, was an aspect of our visit to Machu Piccu, it was somewhat rigid, in that it was restricted to the lower levels of the monument. I, and several other members of the group would very much like to have climbed to the top level , in order to gain more of an overview of the site

Active and outdoorWildlife

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

16-99 yrs

Operated in

english

Destinations

Cusco, Guayaquil, Sierra Negra

Cusco, Guayaquil, Sierra Negra, Tintoreras Island, Galapagos Islands, Tortuga Bay, Quito, Aguas Calientes, Puerto Villamil

Duration15 days

From

USD 4,920

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Rio de Janeiro to Buenos Aires (via Iguazu) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from the vibrant streets of Rio de Janeiro to the cultural heart of Buenos Aires, seamlessly connecting you through the awe-inspiring Iguazu Falls. This immersive travel pass offers unique experiences like exploring Brazil's iconic Christ the Redeemer, hiking the lush rainforest, and reveling in Argentina's vibrant tango scene. Perfect for wanderlust-driven explorers, this journey promises unparalleled natural beauty, cultural richness, and thrilling activities, ensuring memories that last a lifetime. Discover South America's best-kept secrets today!

AdventureActive and outdoor

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pu

Buenos Aires, Rio de Janeiro, Puerto Iguazu, Ilha Grande, Paraty, Sao Paulo, Foz Do Iguacu

Duration12 days

From

USD 1,172

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Santiago to Patagonia - 14 days - October 2025

No booking fees

Best price guaranteed

Discover Chile in all its glorious natural beauty from the glittering lakes of Puerto Varas, the scenic archipelago of Chiloé, the panoramic views from Punta Arenas and the jagged granite peaks of the Paine massif. Along the way visit traditional fishing villages, observe comical penguins and explore Torres del Paine national park in your way.

Sightseeing ToursWaterfalls

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Santiago, Punta Arenas, Torres D

Santiago, Punta Arenas, Torres Del Paine, Puerto Varas, Peulla, Chiloe National Park, Santiago

Duration14 days

From

USD 8,575

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Charming Peru and Colombia - October 2025

Trip customizable

Best price guaranteed

Take a trip to two of the most breathtaking countries in Latin America! With this 13-day small-group tour of Peru and Colombia, you will discover extraordinary attractions, sacred sites, and breathtaking landscapes which are full of history! Begin your tour in Lima, the "City of Kings" famous for its colonial architecture, extraordinary museums, and delicious cuisine. Catch a flight to Cusco and fly over the Andes Mountains, drive through the Urubamba Valley, and explore Machu Picchu, the Lost City of the Incas. Travel through the Sacred Valley of Peru and visit Cusco with a trip to the Santo Domingo Convent. From there you will fly to Bogota, the capital of Colombia and one of the highest capital cities in the world! Visit the Plaza de Bolívar and La Candelaria, two major city highlights, and enjoy the breathtaking views from Montserrate Hill. From there you will travel to the Coffee Triangle to learn about the rich cultural and natural heritage of the region. This is the perfect way to get acquainted with Colombia’s best-known secret — its delicious coffee. End your tour in Cartagena, a breathtaking coastal city in the Caribbean lowlands bordered by magnificent mountains and the Pacific Ocean. Discover the extraordinary lava beaches loved by locals and tourists!

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

8-99 yrs

Operated in

english

Destinations

Lima, Cartagena, Sacred Valley

Lima, Cartagena, Sacred Valley, Armenia, Urubamba, Cusco, Bogota

Duration13 days

From

USD 2,887

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Ushuaia to Santiago (Ruta 40) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Patagonian adventure from snow-capped Ushuaia to vibrant Santiago along iconic Ruta 40. Discover pristine landscapes, immersive cultural encounters, and thrilling outdoor activities. Highlights include exploring the picturesque Glacier National Park, hiking in stunning El Chaltén, and marveling at the surreal Atacama Desert. Dive into local Argentine and Chilean traditions while indulging in exceptional gastronomy. Experience the ultimate South American journey with diverse terrains, breathtaking vistas, and memorable moments tailored for adventurous travelers.

Active and outdoor

Tour Type

Group Tour

Accommodation

Hotel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Ushuaia, Pucon, El Cal

Santiago, Ushuaia, Pucon, El Calafate, El Chalten, Perito Moreno Glacier, San Carlos de Bariloche, Puerto Varas

Duration12 days

From

USD 1,394

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All Andes Tours in October 2025

Page 5 of 1,301 Trips in Andes during October 2025 with 1,543 Reviews

Best of Argentina, Uruguay & Brazil - October 2025

Best of Peru And Chile - October 2025

19-Day Journey through South America - October 2025

Explore Peru, Argentina & Brazil - October 2025

Santiago to Ushuaia (Ruta 40) Travel Pass - October 2025

Salta to La Paz Salt Flats Adventure 10D/9N - October 2025

Rio de Janeiro & Iguassu Falls Experience - October 2025

Mountains to the Lakes - October 2025

Best Of Peru Argentina And Brazil - October 2025

Machu Picchu and Galapagos - October 2025

Rio de Janeiro to Buenos Aires (via Iguazu) Travel Pass - October 2025

Santiago to Patagonia - 14 days - October 2025

Charming Peru and Colombia - October 2025

Ushuaia to Santiago (Ruta 40) Travel Pass - October 2025

Page 5 of 1,301 Trips in Andes during October 2025 with 1,543 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Andes Tours in October 2025

Page 5 of 1,301 Trips in Andes during October 2025 with 1,543 Reviews

Page 5 of 1,301 Trips in Andes during October 2025 with 1,543 Reviews