20 Best Tours and Trips in Panama City in 2026/2027 - Compare Prices

Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

Costa Rica & Panama Discovery

(2 reviews )

No booking fees

Best price guaranteed

Looking to get beneath the surface of Central America? The 12-day 'Costa Rica & Panama Discovery' tour introduces you to the vibrant rhythms and hidden gems of Costa Rica and Panama, beginning in San Jose and winding down in Panama City. With a mix of included activities and free time, you’ll visit the indigenous Ngabe-Bugle community on Isla Popa, learn Caribbean cooking, spot wildlife on jungle walks, and even get a close-up look at the Panama Canal’s engineering marvels. Perfect for explorers drawn to culture and history, this tour package stands out for its access to off-the-beaten-path communities, offering authentic experiences rarely found on standard itineraries. All accommodation, meals, and transport are included, ensuring a smooth and engaging cultural sightseeing journey.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Panama City, San Jose, Puerto Vi

Panama City, San Jose, Puerto Viejo de Talamanca, Chitre, Isla Colon, Bocas Del Toro, Boquete

Duration12 days

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Central American Explorer

4.8

(13 reviews )

No booking fees

Best price guaranteed

A very enjoyable tour with an excellent and informative tour leader who always went the extra mile to ensure things ran smoothly. Perhaps the only criticism is that it needs to be stressed in the trip notes that although crossing the Gulf of Fonseca by boat is an adventure it’s going to be rather wet.

Active and outdoorExplorer

Tour Type

Small Group Tour

Accommodation

Hotel, Eco Lodge, Lodge, Villa

Age Range

16-99 yrs

Operated in

english

Destinations

Panama City, Antigua, Rincon de

Panama City, Antigua, Rincon de la Vieja Volcano National Park, Isla De Ometepe, Granada, Leon, San Salvador, Suchitoto, Panama Canal, Copán Ruinas, Boquete, Bocas Del Toro, Sarapiqui, Arenal, Monteverde Cloud Forest Biological Preserve

Duration25 days

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Cycle Nicaragua to the Panama Canal

4.6

(10 reviews )

No booking fees

Best price guaranteed

An excellent way to explore Central America on two wheels—what a ride! I loved every segment of the tour. Just a heads-up: you’ll need more than basic cycling skills… and a truckload of grit. Some of the dirt roads, especially the downhills, are the kind that make you suddenly remember every loved one you’ve ever had. Definitely not for the faint-hearted. About the hotels: a few of the one-night stays were… let’s say “character-building.” The stop in Turrialba in particular did not meet even basic standards. Explore, you can do better—please save future cyclists from that experience. Now, about our tour leader, Mike. After ~15 tours across ~20 countries, I’ve finally had a tour led by a real pro athlete. And wow—what a difference. Mike’s professionalism, enthusiasm, ocean-level patience, and that trademark toothy smile made even the toughest (undualating😄）climbs feel manageable. He set the bar so high that my future tours may need oxygen just to reach it. Absolutely recommended. And if you’re lucky enough to get Mike, prepare to have your expectations ruined—in the best possible way.

Active and outdoor

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Panama City, San Jose, Granada

Duration14 days

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Best of Panama

(2 reviews )

Trip customizable

Best price guaranteed

Nice Trip and amazing arrangements. Will love to travel again!

Cultural, religious and historic sites

Tour Type

Independent Tour

Accommodation

Hotel

Age Range

8-99 yrs

Operated in

English

Destinations

Panama City, Boquete, San Blas I

Panama City, Boquete, San Blas Islands, Isla Colon, Bocas Del Toro

Duration12 days

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Treasures of Costa Rica and Panama

(1 review )

Trip customizable

Best price guaranteed

We loved our trip to Costa Rica/Panama and it was a perfect mix of tours and time on our own. The guides were all great and the hotels (including breakfast) all good -- one less so but not bad... Highly recommend this trip!

National parksWildlife

Tour Type

Small Group Tour

Accommodation

Hotel, Villa

Age Range

8-99 yrs

Operated in

english

Destinations

Panama City, San Jose, Panama Ca

Panama City, San Jose, Panama Canal, Soberanía National Park, Arenal, Monteverde, Manuel Antonio

Duration13 days

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Amazing Central America

No booking fees

Best price guaranteed

Ready for a month of discovery? The 'Amazing Central America' trip offers 28 days of vibrant exploration, journeying from Antigua to Panama City. This easy-paced tour is crafted for travelers who want to delve into the region’s cultural and natural wonders, from Guatemala’s carved temples to the humming cloud forests of Monteverde. Spend three nights unwinding in the tropical paradise of Bocas del Toro and deepen your understanding of Central American cuisine with hands-on cooking lessons from locals. The standout feature of this tour package is its commitment to authentic experiences—connecting you to the heart and soul of each destination. With accommodations, transportation, meals, and expert guidance included, this cultural journey promises a seamless and insightful adventure.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Hut

Age Range

15-99 yrs

Operated in

english

Destinations

Panama City, San Jose, Antigua

Panama City, San Jose, Antigua, Monteverde Cloud Forest Biological Preserve, Puerto Viejo de Talamanca, Cahuita National Park, Granada, Monteverde, La Fortuna, Sarapiqui, Copan, Bocas Del Toro, Boquete, Chitre, Suchitoto, El Cuco, Leon

Duration27 days

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Best of Central America

No booking fees

Best price guaranteed

If you’re ready to discover Central America’s most spectacular spots, the 44-day 'Best of Central America' trip is your ticket to adventure. Starting in Playa Del Carmen and concluding in Panama City, you'll journey through a mosaic of destinations, from Yucatan’s turquoise waters to the cloud forests of Antigua and the volcanic terrain of Costa Rica. Ideal for travelers who love a laid-back exploration, this wildlife-focused tour package is loaded with opportunities for bird watching, cultural encounters, and time to relax on idyllic beaches. What makes this tour unique is its blend of nature and culture—you’ll meet local residents, sample regional cuisines, and enjoy both guided highlights and the freedom to roam. All logistics are taken care of, with accommodations, meals, and transport included for a carefree, comprehensive journey.

WildlifeCity sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Panama City, Playa Del Carmen, R

Panama City, Playa Del Carmen, Rio Dulce, Antigua, Quetzaltenango, Panajachel, Tulum, Copan, Suchitoto, La Libertad, Leon, Granada, Monteverde, La Fortuna, San Jose, Sarapiqui, Puerto Viejo de Talamanca, Bocas Del Toro, Caye Caulker, Boquete, Chitre, San Ignacio, Flores

Duration45 days

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Ultimate Central America

No booking fees

Best price guaranteed

Embark on the ultimate 58-day journey through Central America, stretching from the cultural vibrancy of Mexico City to the engineering marvels of Panama City. This 'Ultimate Central America' tour is tailored for curious travelers eager for an easy-paced yet immersive sightseeing experience. Travel through eight countries—Mexico, Belize, Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica, and Panama—uncovering remote villages, ancient ruins, lush cloud forests, and pristine Caribbean beaches. The highlight of this tour package is its unmatched depth: you’ll blend in with local communities, encounter rare wildlife, and even explore underwater worlds. With all accommodations, meals, transport, and expert guidance included, this city sightseeing trip is a comprehensive adventure that captures Central America’s spirit like no other.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Mexico City, Panama City, Palenq

Mexico City, Panama City, Palenque, Merida, Playa Del Carmen, Chetumal, Caye Caulker, San Ignacio, Flores, Rio Dulce, Antigua, Quetzaltenango, Puebla, Panajachel, Copan, Suchitoto, La Libertad, Leon, Granada, Monteverde, La Fortuna, San Jose, Sarapiqui, Oaxaca, Puerto Viejo de Talamanca, Bocas Del Toro, Boquete, Chitre, San Cristobal De Las Casas

Duration59 days

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Central and South American Adventure: From Costa Rica to Colombia

No booking fees

Best price guaranteed

Phones charged and playlists queued — this 27-day journey is a full-on adventure through Central and South America that’s packed with wild nature, laid-back beach towns, and buzzing cities. Start in Costa Rica with the surfy chill of Puerto Viejo before heading into Panama’s hidden gems — think island time in Bocas del Toro, misty hikes in Boquete, and the crater village of Valle de Antón. Then go fully off-grid on the San Blas Islands, where Indigenous communities run the show and turquoise water meets white sand. After that, it’s Colombia time. Wander Cartagena’s colourful old town, trek through jungle trails to waterfalls in Minca, kick back in Santa Marta, and finish strong in Medellín with mountaintop views and a nightlife scene to match. From slow travel moments to fast-paced fun, this one’s got it all.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hostel, Hotel, Hut, Villa

Age Range

18-39 yrs

Operated in

english

Destinations

San Jose, Medellin, Valle De Ant

San Jose, Medellin, Valle De Antón, Panama City, San Blas Islands, Cartagena, Puerto Viejo de Talamanca, Minca, Palomino, Tayrona National Park, Santa Marta, Bocas Del Toro, Boquete

Duration27 days

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Total Central America: Two Months of Wild

No booking fees

Best price guaranteed

Two months. Seven countries. One unforgettable ride. This all-out Central American adventure kicks off in Mexico City with tacos, mole, and big energy — then it’s full speed ahead through mountains, jungles, highlands, beaches, and islands. You’ll snorkel in Belize, boat across Lake Atitlán, crash with a local fam on Nicaragua’s Ometepe Island, and dance the night away in Panama City. Whether you’re soaking in cloud forest vibes in Costa Rica or chilling barefoot on the San Blas Islands, this trip is the ultimate way to see it all. From street eats to off-the-grid retreats, it’s two months of pure adventure — and it’s calling your name.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Home-stay, Hostel, Hotel, Hut, Resort

Age Range

18-39 yrs

Operated in

english

Destinations

Mexico City, Panama City, Bacala

Mexico City, Panama City, Bacalar, Valladolid, Tulum, Playa Del Carmen, Caye Caulker, San Ignacio, Flores, Rio Dulce, Antigua, Panajachel, San Juan La Laguna, Oaxaca, Copan, Suchitoto, La Libertad, Leon, Granada, Isla De Ometepe, Monteverde, La Fortuna, San Jose, Puerto Viejo de Talamanca, Bocas Del Toro, San Cristobal De Las Casas, Boquete, Valle De Antón, San Blas Islands, Palenque

Duration62 days

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All Panama City Tours and Trips

Create a customized tour to Panama City and Panama

24 Trips in Panama City with 28 Reviews

24 Trips in Panama City with 28 Reviews

Costa Rica & Panama Discovery

Central American Explorer

Cycle Nicaragua to the Panama Canal

Best of Panama

Treasures of Costa Rica and Panama

Amazing Central America

Best of Central America

Ultimate Central America

Central and South American Adventure: From Costa Rica to Colombia

Total Central America: Two Months of Wild

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

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All Panama City Tours and Trips

Create a customized tour to Panama City and Panama

24 Trips in Panama City with 28 Reviews

24 Trips in Panama City with 28 Reviews