10 Best South America Multiday Tours in April 2026

Treasures of the Incas - April 2026

4.9

(10 reviews )

No booking fees

Best price guaranteed

Incredible knowledge displayed by the local tour experts. Our Trip Liaison, was very responsive to our questions and adapted very well when a regional Peruvian flight was changed by the airline at the last minute.

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel

Age Range

5-99 yrs

Operated in

english

Destinations

Lima, Puno, Sacred Valley, Machu

Lima, Puno, Sacred Valley, Machu Picchu, Cusco

Duration12 days

From

USD 8,134

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Andes Day Hike - in National Park Yerba Loca - April 2026

(1 review )

Trip customizable

Best price guaranteed

This was a perfect trip for those who want to get out of Santiago and step into nature for the day. The valley was beautiful and the hike was perfect, not too difficult. The picnic at the end of the hike was the cherry on top of this tour.

Trekking and HikingWildlife

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Santiago

Duration6 hours

From

USD 175

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Lake Titicaca Catamaran 2D/1N (La Paz to La Paz) - April 2026

No booking fees

Best price guaranteed

Embark on an unforgettable journey from La Paz to the breathtaking Lake Titicaca. Experience a luxurious catamaran ride across the world’s highest navigable lake, visiting the mystical Sun and Moon Islands. Engage in captivating cultural exchanges with local indigenous communities and explore ancient Incan ruins. Marvel at stunning Andean landscapes, relish delicious traditional cuisine, and enjoy comfortable onboard amenities. This is a perfect adventure for those seeking to blend nature, history, and luxury in one incredible tour.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Lake Titicaca, Andes Mountains

Duration2 days

From

USD 1,046

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Transfer In Aeroparque-Hotel Without Tour Guide - April 2026

Trip customizable

Best price guaranteed

Send us the details of your arrival flight to the airport, and after your payment, a driver will be waiting for you in the landing area with a sign in your name, to transfer it quickly and safely to your hotel in downtown Buenos Aires. We also have van service, so for more passengers, do not hesitate to contact us

Ground transfers

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 42

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Lake Titicaca & Isla del Sol Adventure 2D/1N (Copacabana to La Paz) - April 2026

No booking fees

Best price guaranteed

Embark on an unforgettable journey through Copacabana and Isla del Sol with Bamba's exclusive tour. Explore the serene beauty of Lake Titicaca while immersing yourself in rich cultural experiences. Discover ancient Inca temples, hike to panoramic viewpoints, and soak in breathtaking landscapes. With guided excursions and cozy accommodations, this adventure promises a blend of history, adventure, and natural splendor. Perfect for travelers seeking an authentic Bolivian adventure, this tour ensures a memorable escape.

AdventureExplorerBicycle tours

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel, Eco Lodge, Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Copacabana, Isla Del Sol

Duration2 days

From

USD 220

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Lake Titicaca & Isla del Sol Adventure 2D/1N (La Paz to Copacabana) - April 2026

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from La Paz to explore the mystical Lake Titicaca and Isla del Sol. Revel in stunning Andean landscapes, visit ancient Incan ruins, and immerse yourself in the rich culture of Copacabana. This exclusive journey includes scenic boat rides, guided treks, and authentic local interactions, ensuring a truly immersive experience. Perfect for adventure seekers and culture enthusiasts, this tour offers a unique blend of natural beauty and historical intrigue, creating cherished memories.

AdventureExplorer

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Hostel, Eco Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Copacabana, Isla Del Sol

Duration2 days

From

USD 220

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Private tour: Snow, Mountain & Wine Tour - All in one! - April 2026

Trip customizable

Best price guaranteed

Would you like to get to know the Andes, breathe the fresh air, walk in the snow, but don’t necessarily feel like skiing? Join us on a combo tour of snow, mountain & wine, where we first visit the Valle Nevado ski resort in the morning, followed by a wine tour & tasting at the oldest vineyard in Chile, Cousiño Macul, in the Maipo valley! Before starting our wine tour, we will have lunch at an amazing French-style restaurant downtown in Providencia. They have a very varied menu, with amongst others confit de canard, warm goat cheese salad, pastas, filets and a huge collection of wines! You will be picked up at 07.30 and returned by 18.00 maximum to your hotel (2 hours up to Valle Nevado, 1.5 hour down to Santiago, 1 hour from Santiago to the winery & restaurant).

Wine tasting tours

Tour Type

Private Tour

Accommodation

Hotel, Resort

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Santiago

Duration10 hours

From

USD 210

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Safari a las Nubes from Salta - April 2026

Trip customizable

Best price guaranteed

Do not miss one of the most incredible tours in Salta! We will follow the Road to the Clouds, La Puna cross by Route No. 40, the Cuesta de Lipán and San Antonio de los Cobres. We will take the tour on board specially designed vehicles to appreciate the transition of landscapes and feel maximum adrenaline, accompanied by expert guides that will explain everything that we see in our path

Wildlife safaris and game drives

Tour Type

Small Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

Salta, Purmamarca

Duration1 day

From

USD 950

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El Querandi Dinner & Tango Show with transfers - April 2026

Trip customizable

Best price guaranteed

El Querandí, is one of the most popular tanguerias in San Telmo neighborhood. Its beautiful decor with a style of the early twentieth century provides back in time to enjoy an amazing spectacle. In addition to its beautiful architecture, it can accommodate 120 people in a friendly and intimate atmosphere. The tanguería provides excellent cuisine with open bar. The show traces the history of Tango with different dance partners and singers who not only remain on stage but go across the lounge in different numbers of the show

Culture shows and excursions

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 117

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Rainbow Mountain Trek 2D/1N - April 2026

No booking fees

Best price guaranteed

Embark on an exhilarating two-day trek through Peru's stunning landscapes, journeying from the historic city of Cusco to the awe-inspiring Rainbow Mountain. Experience the vibrant culture of local villages, marvel at unique wildlife, and relish the picturesque vistas of the Red Valley. This adventure promises an unforgettable exploration of Peru's natural wonders and cultural richness.

ExplorerTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Camping, Tent

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Vinicunca Rainbow Mountai

Cusco, Vinicunca Rainbow Mountain Trek, Ausangate

Duration2 days

From

USD 357

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Super Sales

Arequipa And Colca Canyon - April 2026

(1 review )

Trip customizable

Best price guaranteed

It has been a FANTASTIC trip. First of all because we have enjoyed a lot of the country, the food, the kindness of the people, extraordinary with us. And second, because of the great quality of the work you have done. We could not be better taken care of! The hotels were fabulous, and everything has been easy. The scheduled trips always on time at the airport and the hotel, and showing themselves charming with us. In addition to the guides, great professionals, with whom we have enjoyed a lot (All of them have been fantastic, but I would like to emphasize to Mauricio, the guide who picked us up in Arequipa and accompanied us through the Colca Valley.

Art and architecture

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

6-99 yrs

Operated in

english, spanish

Destinations

Arequipa, Colca Canyon

Duration4 days

From

USD 427

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4-Day Salta Tour - April 2026

(1 review )

Trip customizable

Best price guaranteed

I sent an email to the tour operator only a couple weeks before arriving in Salta. Mateo from their company arranged 3 full day tours - even though one fell on a major holiday - the 200th anniversary of Argentina's independence! He is clearly one of the most knowledgable travel agents we have ever used. The first day our tour took us to almost 14,000 feet - the viaduct where the train to the clouds travels. Being with him was so much better than a long bus ride and 20 km on the train!! He constantly checked on us to make sure we were not getting sick from the altitude. He adjusted our trip to stop and see everything, or just to take pictures. When we arrived back in Salta, he made sure we had great local food for dinner. The second day, Mateo again arrived bright and early so that we could see all the little villages on our way to Cafayate. As we drove through the amazing views, Mariano knew exactly where to stop to avoid the crowds. He picked an amazing inn outside of the city for lunch, so that we would not fight the crowds. AND he was incredibly patient as we walked the mercado in search of a chess set!! Our days in Salta and jujuy were wonderful and left us wanting more!!! We all highly recommend their travel agency, ask for Mateo and hold on for the ride!!!

Natural landmarks sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Salta, Cafayate, Purmamarca

Duration4 days

From

USD 1,200

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Small Group to the Rainbow Mountain - April 2026

(2 reviews )

Trip customizable

Best price guaranteed

The tour was amazing, the colors of the mountain are incredible, and plus a good guide the expirience was amazing. the food and the transportation also very good.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-79 yrs

Operated in

english, spanish

Destinations

Cusco

Duration1 day

From

USD 65

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Tigre Delta Day Trip by Boat - April 2026

Trip customizable

Best price guaranteed

Our Tigre Delta Day Trip by Boat is ideal for those who would like to explore the Delta of Parana and Uruguay rivers. It includes a boat trip departing from Puerto Madero trough the Rio de la Plata and the Delta area where we will enjoy of the best views of Buenos Aires. We will have lunch in Tigre. We will visit the Puerto de Frutos market. We get back by Train ending up the tour in Retiro Station

Local boat rides

Tour Type

Small Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 221

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All South America Tours in April 2026

Page 48 of 1,581 Trips in South America during April 2026 with 3,904 Reviews

Treasures of the Incas - April 2026

Andes Day Hike - in National Park Yerba Loca - April 2026

Lake Titicaca Catamaran 2D/1N (La Paz to La Paz) - April 2026

Transfer In Aeroparque-Hotel Without Tour Guide - April 2026

Lake Titicaca & Isla del Sol Adventure 2D/1N (Copacabana to La Paz) - April 2026

Lake Titicaca & Isla del Sol Adventure 2D/1N (La Paz to Copacabana) - April 2026

Private tour: Snow, Mountain & Wine Tour - All in one! - April 2026

Safari a las Nubes from Salta - April 2026

El Querandi Dinner & Tango Show with transfers - April 2026

Rainbow Mountain Trek 2D/1N - April 2026

Arequipa And Colca Canyon - April 2026

4-Day Salta Tour - April 2026

Small Group to the Rainbow Mountain - April 2026

Page 48 of 1,581 Trips in South America during April 2026 with 3,904 Reviews

Tigre Delta Day Trip by Boat - April 2026

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Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in April 2026

Page 48 of 1,581 Trips in South America during April 2026 with 3,904 Reviews

Page 48 of 1,581 Trips in South America during April 2026 with 3,904 Reviews