20 Best Tours and Trips in Santa Cruz in 2026/2027 - Compare Prices

Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

Ecuador: Volcanoes, the Amazon & the Galápagos Islands

(8 reviews )

No booking fees

Best price guaranteed

I would recommend Gadventures to anyone. Love that all the planning is done for me. Well organized and friendly guides.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

18-100 yrs

Operated in

english

Destinations

Quito, Isabela Island, Santa Cru

Quito, Isabela Island, Santa Cruz, Cotopaxi National Park, Banos, Amazon Ecuador

Duration15 days

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Galápagos – West and Central Islands aboard the Reina Silvia Voyager (Cruise Only)

(3 reviews )

No booking fees

Best price guaranteed

Variety of food could have been more varied, smash at every meal and the same green salad. but the food was all well prepared and tasty. i liked the trip very much and would recommend it. the pre trip info pack needs review it offer inaccurate and out of date information.

Marine wildlifeCruiseBeach

Tour Type

Small Group Tour

Accommodation

Ship Cabin

Age Range

12-100 yrs

Operated in

english

Destinations

Galapagos Islands, Baltra Island

Galapagos Islands, Baltra Island, Santa Cruz, Punta Cormorant, Punta Moreno, Isla Fernandina, Punta Vicente Roca, Puerto Egas, North Seymour Island

Duration8 days

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Best of Ecuador and Galapagos Islands

(2 reviews )

Trip customizable

Best price guaranteed

This was one of my favorite trips. The itinerary was good, our tour guide was excellent and the small group tours allow for more flexibility more time at locations when everyone agreed to make small changes. Their prices are also very reasonable even as a single traveler.

Beach

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

8-99 yrs

Operated in

english

Destinations

Quito, Santa Cruz, Amazon Ecuado

Quito, Santa Cruz, Amazon Ecuador, Isla Santa Cruz, Isabela Island, Otavalo, Papallacta, Amazon Jungle Lodge, Banos, Guayaquil

Duration12 days

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The Galápagos: Wildlife of Santa Cruz & Isabela Islands

(4 reviews )

No booking fees

Best price guaranteed

This was a trip of a lifetime! G adventures and our CEO's, Felipe and Gustavo, made everything so enjoyable and easy! Getting to the Galapagos was no easy feat and our CEO's handled everything with professionalism and enthusiasm. I felt like I was able to show up and not have to think about anything. I will definitely be booking Gluxe adventures again!

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-100 yrs

Operated in

english

Destinations

Quito, Galapagos Islands, Isabel

Quito, Galapagos Islands, Isabela Island, Santa Cruz

Duration8 days

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Essential Ecuador And Peru

(1 review )

Trip customizable

Best price guaranteed

Hotels were good and except for the one in Cusco, they were very well located. Itinerary was great. I was met with friendly guides and drivers at each stage. City tours were excellent.

Wildlife

Tour Type

Group Tour

Accommodation

Hotel

Age Range

8-99 yrs

Operated in

english

Destinations

Cusco, Lima, Galapagos Islands

Cusco, Lima, Galapagos Islands, Guayaquil, Sacred Valley, Quito, Santa Cruz, Puerto Ayora

Duration11 days

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Galápagos – Central and East Islands aboard the Reina Silvia Voyager (Cruise Only)

(4 reviews )

No booking fees

Best price guaranteed

Absolutely incredible, insightful and eco conscious experience into the heart of the Galapagos, made possible by the superb organisation of G Adventures, the outstanding CEO, Omar Medina and the professional, friendly, able and enthusiastic crew of the Reigna Silvia.

Marine wildlifeBeach

Tour Type

Small Group Tour

Accommodation

Ship Cabin

Age Range

12-100 yrs

Operated in

english

Destinations

Baltra Island, Santa Cruz, Punta

Baltra Island, Santa Cruz, Punta Suárez, Punta Pitt, South Plaza Island, Galapagos Islands, Bartolome Island, Rábida Island

Duration8 days

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Galápagos Express Adventure: Wilderness & Wildlife

(8 reviews )

No booking fees

Best price guaranteed

Excellent experience.

Wildlife

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-39 yrs

Operated in

english

Destinations

Santa Cruz, Puerto Ayora, San Cr

Santa Cruz, Puerto Ayora, San Cristobal Island, Isla Santa Cruz, Isabela Island

Duration7 days

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Machu Picchu & Galapagos Wonders featuring a 4-Night Cruise

(6 reviews )

No booking fees

Best price guaranteed

From ancient Incan mysteries to the wildlife wonders of the Galápagos, the 'Machu Picchu & Galapagos Wonders featuring a 4-Night Cruise' tour is a dream for adventurers who relish discovery. This 14-day guided journey begins in Lima and ends in Santa Cruz, blending challenging trekking and hiking with a luxurious Galápagos cruise. Uncover Machu Picchu’s lost city, explore UNESCO-listed colonial towns, and stand at the Equator’s midpoint. The highlight is a 4-night cruise aboard a personal yacht through the Galápagos archipelago, where you’ll witness rare wildlife and pristine landscapes that inspired Darwin’s theories. This trip’s USP lies in its seamless fusion of cultural heritage and natural marvels—offering an unparalleled adventure from the Andes to the Pacific, with every detail expertly arranged for intrepid, experience-hungry travelers.

Trekking and Hiking

Tour Type

Group Tour

Accommodation

Hotel, Ship Cabin

Age Range

1-99 yrs

Operated in

english

Destinations

Lima, Santa Cruz, Quito

Duration14 days

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Highlights Of Quito And Galapagos Islands

(1 review )

Trip customizable

Best price guaranteed

My wife and I really enjoyed our trip. We never could have managed to see as much of Ecuador & Galapagos and as many sites on our own and the tour made it really easy and pleasurable.

Beach

Tour Type

Group Tour

Accommodation

Hotel

Age Range

8-99 yrs

Operated in

english

Destinations

Quito, Galapagos Islands, Santa

Quito, Galapagos Islands, Santa Cruz, Isla Santa Cruz, Isabela Island

Duration7 days

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Ecuador to Galápagos: Jungle Beats & Island Heat

No booking fees

Best price guaranteed

If wild jungles crystal-clear crater lakes and volcanic island vibes sound like your kind of adventure, Ecuador is about to blow your mind. This 17-day trip kicks off deep in the Amazon where you’ll wake up to monkey calls and fall asleep to jungle symphonies. Pedal through local communities eat your weight in handmade chocolate and soak in the thermal energy of Baños. Then it’s off to Quilotoa — a dreamy turquoise crater lake you’ll hike down to and maybe even kayak across. Just when you think the trip couldn’t get any better you’ll head to the legendary Galápagos Islands for epic snorkelling, volcanic hikes, and more wildlife than your camera roll can handle. This is Ecuador turned all the way up.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

18-39 yrs

Operated in

english

Destinations

Quito, Santa Cruz, Isabela Islan

Quito, Santa Cruz, Isabela Island, San Cristobal Island, Tena, Banos, Quilotoa

Duration17 days

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All Santa Cruz Tours and Trips

Create a customized tour to Santa Cruz and Ecuador

21 Trips in Santa Cruz with 37 Reviews

Ecuador: Volcanoes, the Amazon & the Galápagos Islands

Galápagos – West and Central Islands aboard the Reina Silvia Voyager (Cruise Only)

Best of Ecuador and Galapagos Islands

The Galápagos: Wildlife of Santa Cruz & Isabela Islands

21 Trips in Santa Cruz with 37 Reviews

Essential Ecuador And Peru

Galápagos – Central and East Islands aboard the Reina Silvia Voyager (Cruise Only)

Galápagos Express Adventure: Wilderness & Wildlife

Machu Picchu & Galapagos Wonders featuring a 4-Night Cruise

Highlights Of Quito And Galapagos Islands

Ecuador to Galápagos: Jungle Beats & Island Heat

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

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All Santa Cruz Tours and Trips

Create a customized tour to Santa Cruz and Ecuador

21 Trips in Santa Cruz with 37 Reviews

21 Trips in Santa Cruz with 37 Reviews