10 Best Andes Multiday Tours in October 2025

Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

La Paz To Buenos Aires: Andes & The Atacama Desert - October 2025

27% OFF TODAY

Super Sales

La Paz to Buenos Aires: Andes & the Atacama Desert - October 2025

(4 reviews )

No booking fees

Best price guaranteed

Amazing tour! Salt flats are incredible, the pace of the tour was great, good accommodation and Areli was a fantastic CEO

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel, Hostel, Bungalow

Age Range

18-39 yrs

Operated in

english

Destinations

Buenos Aires, La Paz, San Pedro

Buenos Aires, La Paz, San Pedro De Atacama, Salta, Sucre, Potosi, Uyuni, Salar De Uyuni

27% OFF TODAY

Duration15 days

From

USD 2,499

USD 1,818

Saving

USD 681

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La Paz to Salta Travel Pass - October 2025

No booking fees

Best price guaranteed

Discover the adventure of a lifetime with an exhilarating journey from La Paz to Salta. Embark on vibrant city tours, breathtaking Uyuni Salt Flats excursions, and immersive cultural experiences. Traverse stunning landscapes from Bolivia’s Altiplano to Argentina’s rugged mountains. Enjoy thrilling activities like stargazing, historical site visits, and vibrant local markets. Perfect for adventure seekers and culture enthusiasts, this South American odyssey offers unforgettable memories and unparalleled natural beauty. Join this epic journey and explore some of South America's most iconic destinations!

Sightseeing Tours

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Salta, Candelaria, Lagun

La Paz, Salta, Candelaria, Laguna Colorada, San Pedro De Atacama

Duration9 days

From

USD 906

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22% OFF TODAY

Super Sales

Southern Divide - October 2025

(4 reviews )

No booking fees

Best price guaranteed

The trip was a wonderful experience. We learned quite a bit about the local people and their culture by visiting their communities. Watching the women weave was amazing!

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Resort, Guest House

Age Range

12-100 yrs

Operated in

english

Destinations

Santiago, Lima, La Paz, Sucre, P

Santiago, Lima, La Paz, Sucre, Potosi, Uyuni, Salar De Uyuni, San Pedro De Atacama, Cusco, Ollantaytambo, Aguas Calientes, Puno

22% OFF TODAY

Duration21 days

From

USD 4,499

USD 3,491

Saving

USD 1,008

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Natural Wonders of Argentina and Brazil - October 2025

4.7

(5 reviews )

Trip customizable

Best price guaranteed

The highlight of traveling with you was the promptness and timeliness of service. All Hotels were very good and our favourite excursion was at Iguazu Falls, it was very scenic. All the guides were very good, we are very pleased with the service. Everything was excellent.

City sightseeingNational parks

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, Rio

Buenos Aires, Iguazu Falls, Rio de Janeiro, Iguazu Falls National Park

Duration9 days

From

USD 2,730

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Argentina for true Explorers -15 days - October 2025

4.9

(17 reviews )

Trip customizable

Best price guaranteed

I usually don’t post reviews, but I wanted to thank the staff for helping to make our 2 week Argentinian adventure as flawless as possible. First Melina helped plan our itinerary, which was quite challenging since it included 4 flights and 5 hotels! The activities she suggested, from ice trekking to Tango shows were all fun and unique. The transportation to and from activities and hotels was stellar and such a time saver. We chose mid range hotels and each was clean and so fitting for the location we were at. Milagros took over once our itinerary was set and what a bonus that was! What stood out most was how graciously she accommodated all the issues we had once we began our trip - and there were a lot. From lost luggage to last minute flight and hotel changes, Milagros handled everything graciously and without an upcharge to do so. The farewell bottle of wine was such an unexpected surprise. Muchas Gracias, team!

Active and outdoor

Tour Type

Private Tour

Accommodation

Hotel, Tent

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, El C

Buenos Aires, Iguazu Falls, El Calafate, Ushuaia, El Chalten, Iguazu Falls National Park, Patagonia, Perito Moreno Glacier

Duration15 days

From

USD 3,285

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Galapagos & Peru Adventure - October 2025

10% OFF TODAY

Super Sales

Galapagos & Peru Adventure - October 2025

No booking fees

Best price guaranteed

Visit South America and travel to the Galapagos Islands, Peru, Ecuador, and Bolivia. Amazing wildlife, both on land and underwater, is the drawcard of the remote Galapagos Islands. Discover unique creatures, as well as the island's outstanding natural beauty, by foot, boat and bike. Back on the mainland, enjoy the delights of Peru – from the tough but rewarding Inca Trail to the joy of interacting with friendly locals and experiencing cities full of colour, energy and passion.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Lodge, Eco Lodge, Home-stay

Age Range

15-99 yrs

Operated in

english

Destinations

Quito, La Paz, Lima, Puerto Mald

Quito, La Paz, Lima, Puerto Maldonado, Amazon Lodge Tambopata, Cusco, Ollantaytambo, Inca Trail, San Cristobal Island, Puno, Isla Isabela, Isla Santa Cruz

10% OFF TODAY

Duration24 days

From

USD 8,475

USD 7,622

Saving

USD 853

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Argentina & Brazil Adventure - October 2025

27% OFF TODAY

Super Sales

Argentina & Brazil Adventure - October 2025

(1 review )

No booking fees

Best price guaranteed

Get an invigorating taste of South America’s south on a trip that takes you from Buenos Aires to Rio de Janeiro. Let the sounds of samba wash over you and get swept up in the infectious energy of the locals. Stroll white-sand beaches in Rio, rummage through antique fairs in Buenos Aires and sample delicious culinary specialties wherever you go. In between these two vibrant cities, become immersed in spectacular wilderness - from the sprawling wetlands of Ibera to the astonishing Iguazu Falls, there’s a trove of natural beauty waiting for you.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, It

Buenos Aires, Rio de Janeiro, Ituzaingo, Foz Do Iguazu, Iguazu Falls

27% OFF TODAY

Duration10 days

From

USD 4,470

USD 3,252

Saving

USD 1,218

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Bolivia Highlights Adventure 14D/13N - October 2025

No booking fees

Best price guaranteed

Explore Bolivia like never before with an unforgettable adventure through its most breathtaking landscapes and cultural wonders. Experience the vibrant city of La Paz, marvel at the surreal Uyuni Salt Flats, journey through the heart of the Amazon rainforest, and discover the rich history of Potosi and Sucre. Immerse yourself in local traditions, witness stunning Andean vistas, and embrace thrilling activities like trekking and wildlife spotting. Embrace the ultimate Bolivian escapade filled with unique experiences and unforgettable memories.

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, La Paz, San Juan, Huayll

La Paz, La Paz, San Juan, Huayllajara, Copacabana, Isla Del Sol

Duration14 days

From

USD 1,686

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Nature and culture in Northwest Argentina - October 2025

(13 reviews )

Trip customizable

Best price guaranteed

We visited: Salta, Catchi, Cafayete, Salt -Flat, Purmamarca, Tilcara, Iguazú falls ,Buenos Aires. The whole trip was 100 % organized by the team. Everything was perfect, the hotels, guides, scenery, the whole itinerary. I would recommend this agency for self drive trips!"

WildlifeSightseeing Tours

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, Salt

Buenos Aires, Iguazu Falls, Salta, Iguazu Falls National Park, Jujuy, Cafayate, Posadas, Ibera Wetlands

Duration15 days

From

USD 5,205

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Best Of Argentina & Brazil - October 2025

22% OFF TODAY

Super Sales

Best of Argentina & Brazil - October 2025

No booking fees

Best price guaranteed

Get a taste of the rhythms of Argentina and Brazil on this southern adventure journeying from Buenos Aires to Rio de Janeiro, taking in spectacular Iguazu Falls along the way. From tango to samba, Spanish to Portuguese, and Malbec wine to caipirinhas, these two countries are sure to have you enthralled in their passionate zest for life. Lively Rio de Janeiro is the perfect spot to cap off your South American sojourn, where the beaches of Copacabana or Ipanema beckon and sunset from the top of Sugarloaf Mountain shouldn’t be missed.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Iguazu Falls

22% OFF TODAY

Duration7 days

From

USD 3,805

USD 2,953

Saving

USD 852

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Luxury Food and Wine Tour of Argentina & Chile in 14 days - October 2025

(1 review )

Trip customizable

Best price guaranteed

Spend two weeks exploring the heart of Argentina's as well as Chile’s Southern lakes districts during this fabulous, guided tour. Enjoy the delights of Argentine and Chilean wines and gourmet food along with some of the best natural highlights of the area. Explore Buenos Aires, the 'Paris of South America', where you can enjoy an Argentine dinner along with local wines. Round it up with a stroll along Milongas. Discover Bariloche, the stunning lake region of Patagonia. Cross the Andes from Argentina to Chile enjoying amazing views of lakes, volcanoes and the majestic Andean Mountains. Learn more about the traditional gaucho way of life in San Antonio de Areco and visit ateliers and pulperias in the pampas. What are you waiting for? Book your tour today. See the itinerary for more details.

Wine tasting tours

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Mendoza

Buenos Aires, Santiago, Mendoza, Andes Mountains, Puerto Varas, Patagonia, San Carlos de Bariloche, Puerto Montt, Uco Valley, San Antonio De Areco, Pulperias, Isla Negra

Duration14 days

From

USD 12,600

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Lima To La Paz: Sandboarding & Sunsets - October 2025

22% OFF TODAY

Super Sales

Lima to La Paz: Sandboarding & Sunsets - October 2025

4.8

(6 reviews )

No booking fees

Best price guaranteed

We had an incredible time! Enrique made every activity fun with the energy and local knowledge he brought and it was a truly you get out what you put in experience.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay, Camping, Hostel

Age Range

18-39 yrs

Operated in

english

Destinations

Lima, La Paz, Cusco, Ollantaytam

Lima, La Paz, Cusco, Ollantaytambo, Llactapata, Dead Woman's Pass, Wiñay Wayna, Puno, Lake Titicaca, Huacachina, Nazca, Arequipa, Colca Canyon

22% OFF TODAY

Duration21 days

From

USD 2,999

USD 2,327

Saving

USD 672

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Wild Patagonia for Hikers - October 2025

(5 reviews )

Trip customizable

Best price guaranteed

We just returned from a 5-week trip to South America. The team was AMAZING. They helped us plan a very complex itinerary that included multiple cities in Chile and Peru, a side-trip to Easter Island, Machu Picchu and the sacred valley, and finally Iguazu Falls in Argentina and Peru. The advice they gave and the hotels they chose were truly exceptional. The detailed day-by-day itinerary was very helpful, and all of their in-country partners (e.g., drivers, tour guides) were terrific. Everything went perfectly. Best travel experience ever! Thank you, Analia and Antonella!!!

Trekking and Hiking

Tour Type

Private Tour

Accommodation

Hotel, Camping, Lodge, Tent

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

El Calafate, Ushuaia, Torres del

El Calafate, Ushuaia, Torres del Paine National Park, Punta Arenas, El Chalten, Tierra Del Fuego, Puerto Natales, Patagonia, Perito Moreno Glacier, French Valley, Tierra Del Fuego National Park, Torres Del Paine

Duration16 days

From

USD 4,105

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Santiago to Rio de Janeiro Travel Pass - October 2025

No booking fees

Best price guaranteed

Discover South America's majestic wonders on an unforgettable adventure from Santiago to Rio de Janeiro. Experience the thrill of hiking in Chile's picturesque landscapes, exploring Buenos Aires' vibrant culture, and soaking in Iguazu Falls' breathtaking views. With immersive local activities, cultural encounters, and scenic routes, this tour offers a perfect blend of nature and urban excitement. Ideal for travelers eager to uncover hidden gems, this journey promises an enriching and exhilarating exploration of diverse cultures and stunning scenery. Embark on the ultimate South American expedition today!

Local boat rides

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Puerto

Santiago, Rio de Janeiro, Puerto Iguazu, Florianopolis, Sao Paulo, Paraty, Mendoza, Ilha Grande, Córdoba, Buenos Aires

Duration25 days

From

USD 1,723

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All Andes Tours in October 2025

Page 2 of 1,303 Trips in Andes during October 2025 with 1,556 Reviews

La Paz to Buenos Aires: Andes & the Atacama Desert - October 2025

La Paz to Salta Travel Pass - October 2025

Southern Divide - October 2025

Natural Wonders of Argentina and Brazil - October 2025

Argentina for true Explorers -15 days - October 2025

Galapagos & Peru Adventure - October 2025

Argentina & Brazil Adventure - October 2025

Bolivia Highlights Adventure 14D/13N - October 2025

Nature and culture in Northwest Argentina - October 2025

Best of Argentina & Brazil - October 2025

Luxury Food and Wine Tour of Argentina & Chile in 14 days - October 2025

Lima to La Paz: Sandboarding & Sunsets - October 2025

Wild Patagonia for Hikers - October 2025

Santiago to Rio de Janeiro Travel Pass - October 2025

Page 2 of 1,303 Trips in Andes during October 2025 with 1,556 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Andes Tours in October 2025

Page 2 of 1,303 Trips in Andes during October 2025 with 1,556 Reviews

Page 2 of 1,303 Trips in Andes during October 2025 with 1,556 Reviews