10 Best Andes Multiday Tours in September 2025

Complete Bolivia Highlights 12D/11N - September 2025

No booking fees

Best price guaranteed

Discover Bolivia's breathtaking landscapes and vibrant culture with this immersive adventure. Experience awe-inspiring sights like the Uyuni Salt Flats and the ethereal Laguna Colorada. Wander through the historic streets of La Paz, journey to the serene shores of Lake Titicaca, and explore the lush Amazon rainforest. This tour delivers a perfect blend of natural wonders, cultural heritage, and once-in-a-lifetime experiences, perfect for avid travelers seeking an unforgettable South American escape. Book now for the trip of a lifetime!

Adventure

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Sucre, Uyuni, Atulcha, H

La Paz, Sucre, Uyuni, Atulcha, Huayllajara, Potosi

Duration12 days

From

USD 1,190

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Salkantay Trek to Machu Picchu - September 2025

4.9

(12 reviews )

Trip customizable

Best price guaranteed

Well prepared Salkantay trek 5d/5n zone with Saul G as a guide and Gregorio as a chef and Cesar and Walter as porters. Good food all the way and amazing places to sleep such as the hobbit houses and the star gazing houses the very first night. Bonus was the lomo saltado cooking class and the visit of a coffee farm.

Trekking and HikingCamping

Tour Type

Small Group Tour

Accommodation

Camping, Eco Lodge, Hotel, Lodge, Tent

Age Range

10-65 yrs

Operated in

english, spanish

Destinations

Salkantay, Machu Picchu, Aguas C

Salkantay, Machu Picchu, Aguas Calientes, Humantay, Cusco, Soraypampa, Ccollpapampa, Llactapata

Duration8 days

From

USD 855

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From Buenos Aires to the Jungle & falls - September 2025

(3 reviews )

Trip customizable

Best price guaranteed

The tour operator planned a fantastic trip from Buenos Aires to Iguazú Falls. I would highly recommend the two day tour that allows you to see the falls from Brazil as well as Argentina. Claudia and Julieta were a great team. They were always friendly and extremely responsive. They customize the tour and gave us exactly the experience we wanted. Five stars to these two great women.

City sightseeing

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls

Duration6 days

From

USD 1,605

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Bolivia Explorer 9D/8N - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure through Bolivia's stunning landscapes with a tour that captures the essence of this diverse country. Discover the surreal Uyuni Salt Flats, explore vibrant La Paz, and marvel at ancient ruins in Tiwanaku. Enjoy thrilling activities like mountain biking down the "Death Road" and immerse yourself in local culture with community visits. This tour offers a perfect mix of natural wonders, historical sites, and adrenaline-pumping adventures, making it a top choice for intrepid travelers.

AdventureWildlifeWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Copacabana, Uyuni, Atulc

La Paz, Copacabana, Uyuni, Atulcha, Huayllajara

Duration9 days

From

USD 1,181

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Discovering the Best of Argentina - September 2025

(16 reviews )

Trip customizable

Best price guaranteed

I had an outstanding experience working with the travel team for my trip to Argentina. From the very beginning, their team was professional, responsive, and incredibly knowledgeable about the best destinations and experiences. They tailored the itinerary perfectly to my preferences, ensuring a seamless and stress-free journey. Every detail, from accommodations to excursions, was well thought out, and their local expertise truly made a difference. I especially appreciated their prompt communication and willingness to accommodate any requests. Thanks to the team, my trip was not only memorable but also hassle-free. I highly recommend them to anyone looking for a well-organized and authentic travel experience in Argentina!

City sightseeingNational parks

Tour Type

Private Tour

Accommodation

Hotel, Resort, Tent

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, El C

Buenos Aires, Iguazu Falls, El Calafate, Ushuaia, Perito Moreno Glacier, Mendoza

Duration15 days

From

USD 4,005

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Best of the Andes - September 2025

(1 review )

Trip customizable

Best price guaranteed

The most amazing place I have ever been, such breath taking scenery. Gorgeous friendly people. Loved it

Cultural, religious and historic sites

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english

Destinations

Cusco, Lima, Arequipa, Colca Can

Cusco, Lima, Arequipa, Colca Canyon, Chivay, Puno, Aguas Calientes

Duration10 days

From

USD 1,765

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Colombia's Lost City Trek - September 2025

(1 review )

No booking fees

Best price guaranteed

Wow - this was a challenging hike! Not so much the terrain, definitely due to the hot weather. Putting the heat, sweat and fatigue to one side - this hike is unique and rewarding. Along the route there is lots to see and the destination is mind blowing! Our team (Stiwen, Brayan & Pinnochio) were attentive and did everything possible to make this a safe & memorable trip. The side journeys on this itinerary were all worthwhile and enjoyable. It was just the two of us for the duration of this trip and at all times we felt safe and everything ran without a hitch.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Resort, Camping

Age Range

18-99 yrs

Operated in

english

Destinations

Bogota, Cartagena, The Lost City

Bogota, Cartagena, The Lost City Trek, Santa Marta

Duration10 days

From

USD 2,290

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Lakes, Glaciers and Bohemian Buenos Aires - September 2025

4.9

(10 reviews )

Trip customizable

Best price guaranteed

"Our traveling group had the pleasure of working with the travel team for our trip to Buenos Aires and Patagonia. From start to finish, they were professional, responsive, kind, and very knowledgeable. With keen listening skills, Mery patiently developed a customized travel plan that met our unique desires and needs. Once booked, we had the support of Antonella, who continued to work out more specific details for the trip and actually book all of our hotels, excursions, and transfers. During the trip, as questions or requests arose, Antonella and the customer service team responded quickly and made adaptations that really helped our family enjoy this trip. Our excursion guides were exceptional, and we would work with this company over and over again for our travels to this region! Well done and thanks for making it such a great trip!"

City sightseeingWhale watching

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, El Calafate, Puert

Buenos Aires, El Calafate, Puerto Madryn, Patagonia, San Carlos de Bariloche, Perito Moreno Glacier, Peninsula Valdes

Duration9 days

From

USD 2,915

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Peru Overview - September 2025

Trip customizable

Best price guaranteed

This fabulous trip takes your average tour itinerary and raises the bar to a whole new level! Experience the best of Peru on this once in a lifetime tour. The 15-day tour includes the bucket-list topping Incan city of Machu Picchu in Cuzco, which stands 2,430 meters above sea-level in the middle of a tropical mountain forest, in an extraordinarily beautiful setting. Known as the most amazing urban creation of the Inca Empire at its height; its giant walls, terraces and ramps seem as if they have been cut naturally in the continuous rock escarpments. Other amazing sights include: Lake Titicaca in Puno with its science-defying floating islands; Colca Canyon in Arequipa which slices 10,725 feet into the earth and where tranquility and beauty abounds and where condors slice up the sky; the enigmatic Nazca Lines in Ica; and an overnight stay in the wilds of the Amazon Jungle in Puerto Maldonado.

Cultural, religious and historic sites

Tour Type

Private Tour

Accommodation

Hotel, Lodge

Age Range

5-79 yrs

Operated in

english

Destinations

Cusco, Lima, Puerto Maldonado, A

Cusco, Lima, Puerto Maldonado, Arequipa, Ballestas Islands and Paracas National Reserve, Puno, Aguas Calientes

Duration15 days

From

USD 2,910

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Deserts, Jungle and Falls - September 2025

4.8

(12 reviews )

Trip customizable

Best price guaranteed

I would definitely recommend taking the Jungle boat ride. If you don't like getting wet, then forget about it, because you will get trenched! They give each person a bag to keep your personal items dry, such as your cell phone & other valuables. In this regard, the bag is even big enough for some clothing, so you could wear a bathing suit & place the rest of your clothing inside the bag or bring a change of clothes. You could always wear a very lightweight rain coat, but you'll probably still get wet, just not as trenched. Personally, I found getting soaked was quite refreshing & even enhanced the experience. When i arrives to Iguazu the tour was fully booked, but thanks to Say Hueque they found a place for me before I left Iguazu. They have a great service, I highly recommend traveling with them.

Cultural, religious and historic sites

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, Salt

Buenos Aires, Iguazu Falls, Salta, Purmamarca, Calchaqui Valley

Duration12 days

From

USD 3,270

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Argentina Nature Wonders - September 2025

4.5

(6 reviews )

Trip customizable

Best price guaranteed

Top notch service from this company which I chose for our Argentina trip because they're based in Buenos Aires and have a focus on South America. Clara Gonzalez crafted an experience perfectly in line with our request and did so quickly and accurately. Antonella Pascarelli provided us with the expert support we needed before and during the trip. She informed us of needed documentation, answered detailed questions about hotels and restaurants, handled all hotel stays accurately and made dinner reservations at our choice of restaurants. Land transfers were crucial to our moving about the country and the app included necessary information about that. The guides (Diana in Buenos Aires; Shoam in El Chalten) were both well informed, efficient and personable. I'm glad Antonella knew which companies with whom to work. When we were in country, I received daily emails from Antonella checking in on how things were going and making sure we were on track with the next phase of the trip. I would like to return to South America and I will most certainly try to work with with them.

City sightseeing

Tour Type

Private Tour

Accommodation

Hotel, Tent

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Patagonia, Perito

Buenos Aires, Patagonia, Perito Moreno Glacier, Iguazu Falls, Ushuaia, Beagle Channel Cruise, El Calafate

Duration12 days

From

USD 3,060

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13% OFF TODAY

Super Sales

Journeys: Iconic Peru - September 2025

(7 reviews )

No booking fees

Best price guaranteed

The bucket list locations were wonderfully blended with information and key insights about the history and cultural significance of the locations.

WildlifeTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel, Camping, Villa

Age Range

12-100 yrs

Operated in

english

Destinations

Lima, Cusco, Puno, Tambopata, Ur

Lima, Cusco, Puno, Tambopata, Urubamba, Inca Trail

13% OFF TODAY

Duration14 days

From

USD 3,999

USD 3,491

Saving

USD 508

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Cusco / Machu Picchu Tour By Train - September 2025

(1 review )

Trip customizable

Best price guaranteed

If you like to discover new cultures, customs and feel the peace of nature, this unique tour of Cusco and Machu Picchu is all you need. We hope you will join us for an experience that will change your life. Right through the day or night, Cusco is a city that is full of charms and exciting tourist attractions. The mornings are ideal for strolling Inca streets, visiting colonial churches, visiting the legendary San Blas Artisan Quarter (craftsmen) or visiting Inca villages and archaeological remains. In the evenings, the city dresses up with lights, discos, pubs and restaurants, and its main tourist attractions come alive for visitors. The nightlife in Cusco is fun, exciting and unique, and it's certainly enough to satisfy the most demanding national and foreign visitors. The city of Cusco and Machu Picchu are without a doubt experiences you will cherish all your life.

ExplorerSightseeing Tours

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, japanese, portuguese, spanish

Destinations

Cusco, Aguas Calientes, Machu Pi

Cusco, Aguas Calientes, Machu Picchu, Lima

Duration6 days

From

USD 810

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Journeys: Machu Picchu And The Amazon - September 2025

13% OFF TODAY

Super Sales

Journeys: Machu Picchu and the Amazon - September 2025

(7 reviews )

No booking fees

Best price guaranteed

This was definitely adventure travel with an emphasis on education. It felt like we were there for much longer than we were because each day was packed with wonderful activities. This was my 2nd G Adventures tour and appreciated the upgrades to the National Geographic version. While all of my memories are my favorite, what stands out most was the Amazon experience, the Potato Park venue, the "hidden oasis hotel" in Urubamba, and seeing Machu Picchu after the climb up the stairs. Also - the guides at each destination were also very knowledgeable and outgoing. Loved the whole trip.

WildlifeTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel, Camping, Villa

Age Range

12-100 yrs

Operated in

english

Destinations

Cusco, Lima, Amazon Peru, Amazon

Cusco, Lima, Amazon Peru, Amazon Lodge Tambopata, Urubamba, Ollantaytambo, Dead Woman's Pass, Wiñay Wayna

13% OFF TODAY

Duration10 days

From

USD 3,149

USD 2,749

Saving

USD 400

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All Andes Tours in September 2025

Page 6 of 748 Trips in Andes during September 2025 with 438 Reviews

Page 6 of 748 Trips in Andes during September 2025 with 438 Reviews

Complete Bolivia Highlights 12D/11N - September 2025

Salkantay Trek to Machu Picchu - September 2025

From Buenos Aires to the Jungle & falls - September 2025

Bolivia Explorer 9D/8N - September 2025

Discovering the Best of Argentina - September 2025

Best of the Andes - September 2025

Colombia's Lost City Trek - September 2025

Lakes, Glaciers and Bohemian Buenos Aires - September 2025

Peru Overview - September 2025

Deserts, Jungle and Falls - September 2025

Argentina Nature Wonders - September 2025

Journeys: Iconic Peru - September 2025

Cusco / Machu Picchu Tour By Train - September 2025

Journeys: Machu Picchu and the Amazon - September 2025

Europe

Asia

South America

Africa

North America

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Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Andes Tours in September 2025

Page 6 of 748 Trips in Andes during September 2025 with 438 Reviews

Page 6 of 748 Trips in Andes during September 2025 with 438 Reviews