16-Day South America Tours - Unique 16-Day tours to South America

Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

Black Week Super Sales

Essential Peru - Inti Raymi Festival Departure - 16 days

4.8

(5 reviews )

No booking fees

Best price guaranteed

Guiliano was absolutely amazing. I couldn't have asked for anything more from the trip! There is some long drives as stated but the views and the stops you make are unreal!

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay

Age Range

16-99 yrs

Operated in

english

Destinations

Lima, Cusco, Amantani Homestay

Lima, Cusco, Amantani Homestay, Puno, Colca Canyon, Arequipa, Miraflores, Ica, Nazca, Abancay, Ollantaytambo, Aguas Calientes

Duration16 days

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Black Week Super Sales

Peru: Lima, the Inca Trail & the Amazon - 16 days

4.8

(6 reviews )

No booking fees

Best price guaranteed

This is the way to travel to Peru as the hosts pointed out significant features of where we were which we’d otherwise walk on by. The guides were very knowledgeable and their pride came through in their discussions.

Explorer

Tour Type

Small Group Tour

Accommodation

Camping, Hotel, Lodge, Tent

Age Range

18-100 yrs

Operated in

english

Destinations

Lima, Cusco, Amazon Peru, Sacred

Lima, Cusco, Amazon Peru, Sacred Valley, Inca Trail, Machu Picchu

Duration16 days

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Black Week Super Sales

Best of Peru - 16 days

(2 reviews )

No booking fees

Best price guaranteed

We had a very good trip. Very professional guides for tours and excellent guide for our trek, which help a lot my husband which had some altitude sickness.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Home-stay, Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Lima, Phuyupatamarca, Machu Picc

Lima, Phuyupatamarca, Machu Picchu, Cusco, Lake Titicaca, Puno, Puerto Maldonado, Sacred Valley

Duration16 days

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Black Week Super Sales

The best of Argentina - 16 days

Trip customizable

Best price guaranteed

In this 16 day tour in Argentina you will discovery the most amazing destination of Argentina. You travel from the Jungle and north of Argentina to El Calafate and its Perito Moreno Glacier and Ushuaia, the southernmost city in the world. On this trip, you’ll see the highlights of one of South America’s most beautiful countries. We know that Argentina is a very big country and sometimes it is difficult to select which destination to visit. On this tour the group of our travel experts selected those places that you can not miss if you are travelling to Argentina: Buenos Aires, Iguazu Falls, Salta and Purmamarca, El Calafate and Ushuaia.

Explorer

Tour Type

Independent Tour

Age Range

1-99 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, El C

Buenos Aires, Iguazu Falls, El Calafate, Ushuaia, Salta, Purmamarca, Perito Moreno Glacier, Beagle Channel Cruise, Tierra Del Fuego National Park, Iguazu Falls, Salinas

Duration16 days

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11% OFF TODAY

Black Week Super Sales

Peru & Amazon Experience - 16 days

No booking fees

Best price guaranteed

Embark on an extraordinary odyssey to uncover the beating heart of South America, from the soaring peaks of the Andes to the verdant embrace of the Amazon jungle. This 14-day handcrafted land journey includes chic city stays, a boutique river cruise and an extraordinary train journey to the legendary Machu Picchu. Starting in Lima, you’ll uncover the Peruvian capital’s rich blend of history and modernity. Ascend to the lofty heights of the Sacred Valley before reaching the awe-inspiring Machu Picchu, a World Heritage-listed marvel that speaks to the enduring legacy of ancient civilisations. Explore Cuzco, the imperial capital of the Incas and one of the highest settlements in the world. Then set off into the Amazon on a remarkable river cruise that promises an unparalleled opportunity to immerse yourself in one of the planet's last great rainforests. Delve deep into the untouched wilderness, journey to remote villages, and forge connections with indigenous communities whose traditions have endured for centuries. Finish in Buenos Aires, the colourful and elegant Argentine capital known as the ‘Paris of the Americas’. This is not just a tour – it is an extraordinary journey into the soul of South America.

Cultural, religious and historic sites

Tour Type

Cruise Tour

Accommodation

Hotel, Ship Cabin

Age Range

18-99 yrs

Operated in

English

Destinations

Buenos Aires, Cusco, Lima, Machu

Buenos Aires, Cusco, Lima, Machu Picchu, Amazon Jungle, Sacred Valley, Cuzco

11% OFF TODAY

Duration16 days

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Chile To Argentina: Patagonia Peaks & Campfire Nights - 16 Days

18% OFF TODAY

Black Week Super Sales

Chile to Argentina: Patagonia Peaks & Campfire Nights - 16 days

No booking fees

Best price guaranteed

Got a thing for wild places and once-in-a-lifetime views? This 16-day deep dive into Argentina and Chile is the real deal. Kick things off in buzzing Santiago, then head into volcano country, glacier land, and jaw-dropping Patagonia. You’ll hike to epic viewpoints, soak in hot springs, wander city streets, and camp under southern stars in Torres del Paine. From German-influenced towns to glacier-cracked landscapes, this trip is equal parts culture trip and nature fix. Expect adventure, spontaneity, and a whole crew of new travel besties to share it with.

Explorer

Tour Type

Small Group Tour

Accommodation

Camping, Hostel, Hotel, Tent

Age Range

18-39 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Puerto N

Buenos Aires, Santiago, Puerto Natales, El Calafate, El Chaltén, Pucon, Puerto Varas, Serrano Camp, Laguna Azul

18% OFF TODAY

Duration16 days

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Black Week Super Sales

Contrasts of Argentina Tour - 16 days

Trip customizable

Best price guaranteed

This two week adventurous tour takes you through some of Argentina’s most beautiful and diverse landscapes. You’ll start your tour in Argentina’s never-sleeping capital city of Buenos Aires before heading right down into Patagonia, to Ushuaia and El Calafate, before heading north to the amazing Iguazú Falls. You’ll continue your Argentina odyssey exploring the colorful landscapes and native cultures around Salta and Jujuy in Argentina’s northern desert region. The package includes Transfers, Excursions & Accommodation

Sightseeing Tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

english

Destinations

Buenos Aires, Salta, Iguazu Fall

Buenos Aires, Salta, Iguazu Falls, Humahuaca, Cafayate, Ushuaia, Tierra Del Fuego, El Calafate, Perito Moreno Glacier, Puerto Iguazu

Duration16 days

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Black Week Super Sales

Peruvian Amazon & Machu Picchu Exploration (2027) - 16 days

No booking fees

Best price guaranteed

From a deep dive into Lima—the “City of Kings”—to the legendary Machu Picchu, this 16-day cruise/tour is an all-encompassing adventure into the marvels of Peru and the Amazon rainforest. Journey into the Amazon Rainforest onboard the Aria Amazon, a five-star ship designed for your Peruvian adventure. Embark on river skiffs as you explore the Ucayali and Marañón Rivers. Admire the diverse flora and fauna in the Pacaya-Samiria National Reserve. Discover the beauty of the heartland of the Inka Empire, known as the Sacred Valley. Of course, no trip to Peru could truly be complete without a trek to the world-famous Machu Picchu. A must-see, this spectacular piece of history has fascinated both historians and archaeologists alike. With no shortage of awe-inspiring beauty, this trip is sure to be an unforgettable adventure. Note: The cruise itinerary will vary depending on water levels.

River cruiseHoneymoon

Tour Type

Cruise Tour

Accommodation

Hotel, Ship Cabin

Age Range

2-99 yrs

Operated in

English

Destinations

Lima, Cusco, Aguas Calientes, Iq

Lima, Cusco, Aguas Calientes, Iquitos, San Juan De Yanayacu, Nauta, Pacaya Samiria National Reserve

Duration16 days

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Machu Picchu & Galápagos Island Hopping - 16 Days

13% OFF TODAY

Black Week Super Sales

Machu Picchu & Galápagos Island Hopping - 16 days

(4 reviews )

No booking fees

Best price guaranteed

It was an amazing adventure. Was anxious about travelling in a group but got on really well with everyone. Enjoyed going out for meals with everyone and having a guide to point out what otherwise might have missed. Was nice leaving the organisation to the guide.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hotel, Hut

Age Range

12-100 yrs

Operated in

english

Destinations

Quito, Lima, Floreana Island, Is

Quito, Lima, Floreana Island, Isabela Island, Puerto Ayora, Cusco, Sacred Valley, Aguas Calientes

13% OFF TODAY

Duration16 days

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South America 16-Day Tours and Trips

Page 2 of The Best 16-day Trips in South America with 70,872 Reviews

Page 2 of The Best 16-day Trips in South America with 70,872 Reviews

Essential Peru - Inti Raymi Festival Departure - 16 days

Peru: Lima, the Inca Trail & the Amazon - 16 days

Best of Peru - 16 days

The best of Argentina - 16 days

Peru & Amazon Experience - 16 days

Chile to Argentina: Patagonia Peaks & Campfire Nights - 16 days

Contrasts of Argentina Tour - 16 days

Peruvian Amazon & Machu Picchu Exploration (2027) - 16 days

Machu Picchu & Galápagos Island Hopping - 16 days

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South America 16-Day Tours and Trips

Page 2 of The Best 16-day Trips in South America with 70,872 Reviews

Page 2 of The Best 16-day Trips in South America with 70,872 Reviews