South America Cruise Tours 2024/2025

Explore the serene network of rivers crisscrossing South America, from the Amazon to the Orinoco, on our immersive South America cruise tours. Say farewell to the hassle of daily hotel check-ins and the confines of tour buses—instead, our leisurely and luxurious sailing itineraries allow you to experience the continent’s diverse landscapes in style, similar to the enchantment of a South American hiking tour. Whether your dream is a holiday voyage on the Amazon, a serene sail along the Orinoco towards the Caribbean, or venturing into the icy wilderness of Antarctica, our laid-back South America cruise trips include all the must-see destinations. Embark on a journey to uncover the treasures of this beautiful continent and explore neighboring countries like Peru, Brazil, and Colombia, all within one unforgettable adventure.

Scroll below to find our favorite cruise tours to South America.

Page 5 of 61 Cruise tours with 66 Reviews

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Classic Antarctica - 11 days

  • Best price guaranteed
  • No booking fees
11 day cruise trip to Ushuaia, Drake Passage and 1 other destinations traveling through Argentina and Antarctica. Read More
  • Tour Type Group Tour
  • Activities Cruise
  • Accommodation Ship Cabin
  • Transport Cruise Ship
  • Age Range 18-80 yrs
  • Operated in English
days11 From US$ 7,265 View Tour
Next Departures
  • Nov 12 Only 6 seats left
  • Dec 10 Only 5 seats left
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Antarctic Express: Fly South, Cruise North

  • Best price guaranteed
  • No booking fees
10 day cruise trip to Punta Arenas, South Shetland Islands and 1 other destination in Argentina, Chile and Antarctica. Read More
  • Tour Type Cruise Tour
  • Activities Cruise
  • Accommodation Ship Cabin & Hotel
  • Transport Flight & Cruise Ship
  • Age Range 8-99 yrs
  • Operated in English
days10 From US$ 16,195 View Tour
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Antarctic Express: Cruise South, Fly North

  • Best price guaranteed
  • No booking fees
10 day cruise tour to Ushuaia, Drake Passage and 2 other destinations in Argentina, Chile and Antarctica. Read More
  • Tour Type Cruise Tour
  • Activities Cruise
  • Accommodation Ship Cabin & Hotel
  • Transport Flight & Cruise Ship
  • Age Range 8-99 yrs
  • Operated in English
days10 From US$ 16,795 View Tour
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Emperor Penguin Quest: Expedition to Snow Hill

  • Best price guaranteed
  • No booking fees
14 day cruise tour to Buenos Aires, Ushuaia and 3 other destinations in Argentina, Chile and Antarctica. Read More
  • Tour Type Cruise Tour
  • Activities Cruise
  • Accommodation Ship Cabin, Hotel & Hut
  • Transport Helicopter, Cruise Ship & Flight
  • Age Range 8-99 yrs
  • Operated in English
days14 From US$ 31,295 View Tour
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Patagonia

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  • No booking fees
14 day natural landmarks sightseeing trip to Buenos Aires, El Calafate and 8 other destinations traveling through Argentina and Chile. Read More
  • Tour Type Group Tour
  • Activities Natural landmarks sightseeing & Cruise
  • Accommodation Hotel & Lodge
  • Transport Flight & Boat
  • Age Range 1-95 yrs
  • Operated in English
days14 From US$ 6,699 View Tour
Showing 57 - 61 of 61 results
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South America Cruise Reviews

5 - Excellent
Based on 66 customer reviews
At a loss to come up with adjectives!
5 - Excellent
  • Anonymous
“I am at a loss to come up with adjectives to describe this Expedition. Fantastico! The Expedition was Fantastico! The success of this Expedition was the result of the professionalism and hard work of the entire team. From the Hotel staff to the Ships crew and Expedition staff, this was truly a Team Effort. Everyone involved pulled together to make this a memorable experience. And everyone was in good humour from the moment we stepped aboard. And the Diamond did her part as well. She is well named - truly a Diamond.. Yours in loving Antarctica.”
Quark was the perfect choice.
5 - Excellent
  • Anonymous
“This was a perfect experience for us. We don't want to come home, and we felt both safe when needed and free to explore our surroundings. We wish this tour operator continued success with their hiring such stellar individuals. Additionally, Reniel & Tamara, who took care of our room on the 4th floor, were thoughtful, cheerful & helpful. Dining room staff, especially Andrea, Harrison, Milos and Halim, were so nice to see each day, and actually anticipated our wants. Tracie made fantastic meals and her vibrant personality was a joy. Your behind-the-scenes staff were also pleasant & welcoming when we would meet them in passing. Thank you, thank you, thank you! This was the best decision we've made since getting married. This operator was the perfect choice.”
Overall phenomenal
5 - Excellent
  • Anonymous
“The skiing and mountaineering experiences were amazing and their availability on the Ocean Endeavour is why we chose this boat over others. Getting to go out 3 times for each of these experiences was amazing and far exceeded my expectations. The hotel management was amazing . Rosemarie who cleaned our room was lovely and went above and beyond to make our experience with this tour operator even more memorable. The chef always had the biggest smile I have ever seen on his face . The food and dining room staff were exceptional . The guest experience on board this vessel has been phenomenal”

South America Cruise Tours

Highlights of South America Cruise Tours

  • Embark on an Amazon river cruise tour in South America, encounter exotic wildlife, and connect with indigenous communities as you delve into the heart of the world’s largest rainforest.
  • Cruise through the Beagle Channel to witness Glacier Alley in Tierra del Fuego, where majestic glaciers meet the sea, creating a stunning display of frozen beauty amidst rugged landscapes.
  • Explore the historic Falkland Islands, home to rich avian life and tales of resilience.
  • Embark on a cruise tour adventure to South America that stops at several top sites. Take a trip to Iguazu Falls, and experience its grandeur from both Brazil and Argentina. Then, touch the skies at Machu Picchu, explore the Incan heritage in Cusco, and relish Lima's historic opulence—all UNESCO World Heritage Sites.
  • For the intrepid traveler, Antarctic expeditions offer a chance to explore the icy wilderness and its exceptional wildlife.
  • Encounter the untouched wonder of the Galapagos Islands, where the wildlife showcases the wonders of evolution.

Travel Tips for South America Cruise Tours

  • The best time for cruise tours in South America is during the summer months of the Southern Hemisphere, spanning from November to March. This period offers pleasant weather and vibrant landscapes, enhancing your cruise experience. However, keep in mind that prices might be higher during peak season.
  • Remember to pack comfortable walking shoes and a daypack for daily port visits.
  • Avoid overloading your itinerary with activities; take time to relax and savor the experience.
  • Consider arriving a day or two early to adjust to the local time and culture before setting sail.
  • Be flexible, as weather conditions can occasionally affect schedules, and trust in your captain’s backup plans.
  • Connect with knowledgeable crew members who can provide valuable insider tips to enhance your cruise tour to South America.
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