South America Cruise Tours 2024/2025

Explore the serene network of rivers crisscrossing South America, from the Amazon to the Orinoco, on our immersive South America cruise tours. Say farewell to the hassle of daily hotel check-ins and the confines of tour buses—instead, our leisurely and luxurious sailing itineraries allow you to experience the continent’s diverse landscapes in style, similar to the enchantment of a South American hiking tour. Whether your dream is a holiday voyage on the Amazon, a serene sail along the Orinoco towards the Caribbean, or venturing into the icy wilderness of Antarctica, our laid-back South America cruise trips include all the must-see destinations. Embark on a journey to uncover the treasures of this beautiful continent and explore neighboring countries like Peru, Brazil, and Colombia, all within one unforgettable adventure.

Scroll below to find our favorite cruise tours to South America.

Page 2 of 64 Cruise tours with 66 Reviews

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Pure Brazil

  • Best price guaranteed
  • No booking fees
14 day wildlife tour through Salvador, Foz Do Iguacu, Rio de Janeiro and 4 other destinations in Brazil. Read More
  • Tour Type Small Group Tour
  • Activities Wildlife & Active and outdoor +3 more
  • Accommodation Hotel, Lodge & Eco Lodge
  • Transport Boat, Bus, Flight, Private Vehicle & 4WD Jeep
  • Age Range 16-95 yrs
  • Operated in English
days14 From US$ 6,720 US$ 6,450
SavingUS$ 270
You've unlocked exclusive savings:
  • Brochure Price:US$ 6,720
  • Special Deal (4%):- US$ 270
  • Total Price from:US$ 6,450
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Next Departures
  • Apr 27 Only 8 seats left
  • Jun 15 Only 10 seats left
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Galapagos Islands on Beluga

of 4 reviews
  • Best price guaranteed
  • No booking fees
Hands down one of the best trips I have been on with this company (and this was my 10th one)
  • Tour Type Small Group Tour
  • Activities Cruise
  • Accommodation Ship Cabin
  • Transport Flight, Boat & Bus
  • Age Range 18-99 yrs
  • Operated in English
days08 From US$ 6,450 View Tour
Next Departures
  • Apr 10 Only 2 seats left
  • May 01 10+ seats left
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The Patagonian Fjords of Chile

  • Trip customizable
  • Best price guaranteed
14 day polar expeditions and cruise trip to Ushuaia, Tierra Del Fuego and 8 other destinations in Antarctica, Argentina and Chile. Read More
  • Tour Type Group Tour
  • Activities Polar expeditions and cruise & Cruise +2 more
  • Accommodation Hotel & Ship Cabin
  • Transport Bus, Coach, Private Vehicle & Cruise Ship
  • Age Range 1-79 yrs
  • Operated in English
days14 From US$ 5,790 View Tour
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Classic Antarctica - M/V Greg Mortimer

  • Best price guaranteed
  • No booking fees
12 day cruise trip to Ushuaia, South Shetland Islands and 2 other destinations traveling through Argentina and Antarctica. Read More
  • Tour Type Small Group Tour
  • Activities Cruise & Polar expeditions and cruise
  • Accommodation Hotel & Ship Cabin
  • Transport Cruise Ship
  • Age Range 16-95 yrs
  • Operated in English
days12 From US$ 11,770 View Tour
Next Departures
  • Oct 27 10+ seats left
  • Dec 08 10+ seats left
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South Shetland Islands & Antarctic Peninsula

  • Trip customizable
  • Best price guaranteed
10 day cruise tour to Ushuaia, Drake Passage and 1 other destinations traveling through Argentina and Antarctica. Read More
  • Tour Type Group Tour
  • Activities Cruise & Wildlife +2 more
  • Accommodation Ship Cabin
  • Transport Cruise Ship
  • Age Range 1-79 yrs
  • Operated in English
days10 From US$ 12,375 View Tour
Next Departures
  • Nov 19
  • Dec 06
Add to your Tour Wish List 25% OFFTODAY

Galápagos – West and Central Islands aboard the Reina Silvia Voyager (Cruise Only)

  • Best price guaranteed
  • No booking fees
8 day marine wildlife trip through Santa Cruz, Punta Cormorant, Punta Moreno and 6 other destinations in Ecuador. Read More
  • Tour Type Small Group Tour
  • Activities Marine wildlife & Cruise +1 more
  • Accommodation Ship Cabin
  • Transport Boat, Cruise Ship & Private Vehicle
  • Age Range 12-95 yrs
  • Operated in English
days08 From US$ 6,649 US$ 4,986
SavingUS$ 1,663
You've unlocked exclusive savings:
  • Brochure Price:US$ 6,649
  • Special Deal (25%):- US$ 1,663
  • Total Price from:US$ 4,986
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Next Departures
  • May 25 Only 1 seat left
  • Jun 22 Only 1 seat left
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Treasures of Argentina & Brazil

  • Best price guaranteed
  • No booking fees
10 day cruise trip to Rio de Janeiro, Iguazu Falls and 1 other destinations traveling through Argentina and Brazil. Read More
  • Tour Type Group Tour
  • Activities Cruise & Expedition tours
  • Accommodation Hotel & Ship Cabin
  • Transport Private Vehicle, Boat & Flight
  • Age Range 18-99 yrs
  • Operated in English
days10 From US$ 5,445 View Tour
Next Departures
  • Jan 09 Only 2 seats left
  • Jan 20 Only 2 seats left
Add to your Tour Wish List 28% OFFTODAY

Galapagos Explorer: Central Islands (Grand Queen Beatriz)

  • Best price guaranteed
  • No booking fees
7 day sailing, yachting and motor boating trip in Ecuador, visiting Quito, Isla Baltra and North Seymour Island. Read More
  • Tour Type Small Group Tour
  • Activities Sailing, yachting and motor boating & Wildlife +2 more
  • Accommodation Hotel
  • Transport Boat, Bus, Flight, Ferry & Minibus
  • Age Range 12-99 yrs
  • Operated in English
days07 From US$ 5,235 US$ 3,784
SavingUS$ 1,451
You've unlocked exclusive savings:
  • Brochure Price:US$ 5,235
  • Special Deal (28%):- US$ 1,451
  • Total Price from:US$ 3,784
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Next Departures
  • Apr 16 Only 1 seat left
  • Apr 30 Only 2 seats left
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Galapagos Islands 7-Day Western Cruise Yacht La Pinta

  • Trip customizable
  • Best price guaranteed
7 day expedition trip through Baltra Island, Isla Fernandina, Urbina Bay and 3 other destinations in Ecuador. Read More
  • Tour Type Group Tour
  • Activities Expedition tours & Cruise +2 more
  • Accommodation Ship Cabin
  • Transport Boat, Yacht & Cruise Ship
  • Age Range 1-80 yrs
  • Operated in English, Spanish
days07 From US$ 7,789 View Tour
Next Departures
  • Apr 26
  • Jun 07
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Classic Antarctica - Expedition

  • Best price guaranteed
  • No booking fees
11 day wildlife tour to Ushuaia, South Shetland Islands and 2 other destinations traveling through Argentina and Antarctica. Read More
  • Tour Type Small Group Tour
  • Activities Wildlife & Polar expeditions and cruise +2 more
  • Accommodation Hotel, Resort & Ship Cabin
  • Transport Cruise Ship
  • Age Range 16-79 yrs
  • Operated in English
days11 From US$ 7,160 View Tour
Next Departures
  • Nov 22 10+ seats left
  • Dec 12 10+ seats left
Add to your Tour Wish List 6% OFFTODAY

Brazilian Amazon by Boat

  • Best price guaranteed
  • No booking fees
14 day wildlife trip through Belém, Marajo Island, Monte Alegre and 5 other destinations in Brazil. Read More
  • Tour Type Small Group Tour
  • Activities Wildlife & Active and outdoor +3 more
  • Accommodation Hotel & Camping
  • Transport Boat, Bus, Flight & Ferry
  • Age Range 16-95 yrs
  • Operated in English
days14 From US$ 4,700 US$ 4,430
SavingUS$ 270
You've unlocked exclusive savings:
  • Brochure Price:US$ 4,700
  • Special Deal (6%):- US$ 270
  • Total Price from:US$ 4,430
View Tour
Next Departures
  • May 18 Only 6 seats left
  • Sep 21 Only 10 seats left
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Grand Galapagos (Grand Queen Beatriz)

  • Best price guaranteed
  • No booking fees
17 day sailing, yachting and motor boating tour through Quito, Isla Baltra, Isla Isabela and 11 other destinations in Ecuador. Read More
  • Tour Type Small Group Tour
  • Activities Sailing, yachting and motor boating & Wildlife +2 more
  • Accommodation Hotel
  • Transport Boat, Flight, Minibus & Taxi
  • Age Range 12-99 yrs
  • Operated in English
days17 From US$ 14,025 View Tour
Next Departures
  • Jun 01 Only 2 seats left
  • Jun 15 Only 1 seat left
Add to your Tour Wish List 27% OFFTODAY

Galapagos Encounter: Southern Islands (Grand Queen Beatriz)

  • Best price guaranteed
  • No booking fees
6 day sailing, yachting and motor boating tour in Ecuador, visiting Quito, Baltra Island and Isla Isabela. Read More
  • Tour Type Small Group Tour
  • Activities Sailing, yachting and motor boating & Wildlife +2 more
  • Accommodation Hotel
  • Transport Boat, Flight & Minibus
  • Age Range 12-99 yrs
  • Operated in English
days06 From US$ 3,855 US$ 2,818
SavingUS$ 1,037
You've unlocked exclusive savings:
  • Brochure Price:US$ 3,855
  • Special Deal (27%):- US$ 1,037
  • Total Price from:US$ 2,818
View Tour
Next Departures
  • May 04 Only 4 seats left
  • Jun 01 Only 2 seats left
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Galapagos Islands 5-Day Eastern Cruise Yacht La Pinta

  • Trip customizable
  • Best price guaranteed
5 day expedition tour in Ecuador, visiting Baltra Island, San Cristobal Island and Espanola Island. Read More
  • Tour Type Group Tour
  • Activities Expedition tours & Wildlife +3 more
  • Accommodation Ship Cabin
  • Transport Boat, Bus, Ferry, Yacht & Cruise Ship
  • Age Range 6-80 yrs
  • Operated in English, Spanish
days05 From US$ 5,812 View Tour
Next Departures
  • Apr 18
  • May 02
Showing 15 - 28 of 64 results
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South America Cruise Reviews

5 - Excellent
Based on 66 customer reviews
True professionals
5 - Excellent
  • Anonymous
“We were so impressed with out tour operator team. True professionals with a high level of formal education in their various fields. Most were university graduates. They were so gifted in their areas of expertise and every single team member was helpful and kind. Being older clients we appreciated their assistance and they made us feel respected. Their respect for this Continent shone through too. Thank you all so much. We had the time of our lives ticking our 7th Continent off our Bucket List!!”
Overall phenomenal
5 - Excellent
  • Anonymous
“The skiing and mountaineering experiences were amazing and their availability on the Ocean Endeavour is why we chose this boat over others. Getting to go out 3 times for each of these experiences was amazing and far exceeded my expectations. The hotel management was amazing . Rosemarie who cleaned our room was lovely and went above and beyond to make our experience with this tour operator even more memorable. The chef always had the biggest smile I have ever seen on his face . The food and dining room staff were exceptional . The guest experience on board this vessel has been phenomenal”
Cherished every moment
5 - Excellent
  • Anonymous
“Probably how these expeditions work, but I found the trip quite memorable - the right balance of getting to know and learn about wildlife, marine flora fauna, geology, history & geography, culture of the people in the ship, and adventure with fun. Cherishing every moment here. Not only had the best times in exploring the unknowns but also found the time to reflect within.”

South America Cruise Tours

Highlights of South America Cruise Tours

  • Embark on an Amazon river cruise tour in South America, encounter exotic wildlife, and connect with indigenous communities as you delve into the heart of the world’s largest rainforest.
  • Cruise through the Beagle Channel to witness Glacier Alley in Tierra del Fuego, where majestic glaciers meet the sea, creating a stunning display of frozen beauty amidst rugged landscapes.
  • Explore the historic Falkland Islands, home to rich avian life and tales of resilience.
  • Embark on a cruise tour adventure to South America that stops at several top sites. Take a trip to Iguazu Falls, and experience its grandeur from both Brazil and Argentina. Then, touch the skies at Machu Picchu, explore the Incan heritage in Cusco, and relish Lima's historic opulence—all UNESCO World Heritage Sites.
  • For the intrepid traveler, Antarctic expeditions offer a chance to explore the icy wilderness and its exceptional wildlife.
  • Encounter the untouched wonder of the Galapagos Islands, where the wildlife showcases the wonders of evolution.

Travel Tips for South America Cruise Tours

  • The best time for cruise tours in South America is during the summer months of the Southern Hemisphere, spanning from November to March. This period offers pleasant weather and vibrant landscapes, enhancing your cruise experience. However, keep in mind that prices might be higher during peak season.
  • Remember to pack comfortable walking shoes and a daypack for daily port visits.
  • Avoid overloading your itinerary with activities; take time to relax and savor the experience.
  • Consider arriving a day or two early to adjust to the local time and culture before setting sail.
  • Be flexible, as weather conditions can occasionally affect schedules, and trust in your captain’s backup plans.
  • Connect with knowledgeable crew members who can provide valuable insider tips to enhance your cruise tour to South America.
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