South America Cruise Tours 2024/2025

Explore the serene network of rivers crisscrossing South America, from the Amazon to the Orinoco, on our immersive South America cruise tours. Say farewell to the hassle of daily hotel check-ins and the confines of tour buses—instead, our leisurely and luxurious sailing itineraries allow you to experience the continent’s diverse landscapes in style, similar to the enchantment of a South American hiking tour. Whether your dream is a holiday voyage on the Amazon, a serene sail along the Orinoco towards the Caribbean, or venturing into the icy wilderness of Antarctica, our laid-back South America cruise trips include all the must-see destinations. Embark on a journey to uncover the treasures of this beautiful continent and explore neighboring countries like Peru, Brazil, and Colombia, all within one unforgettable adventure.

Scroll below to find our favorite cruise tours to South America.

Page 4 of 62 Cruise tours with 66 Reviews

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New Year in Antarctica

  • Best price guaranteed
  • No booking fees
12 day cruise trip to Ushuaia, Drake Passage and 1 other destinations traveling through Argentina and Antarctica. Read More
  • Tour Type Group Tour
  • Activities Cruise & Kayaking and canoeing +2 more
  • Accommodation Hotel, Ship Cabin & Camping
  • Transport Cruise Ship
  • Age Range 18-99 yrs
  • Operated in English
days12 From US$ 10,895 View Tour
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Antarctica - A White Christmas

  • Best price guaranteed
  • No booking fees
12 day cruise trip to Ushuaia, Drake Passage and 1 other destinations traveling through Argentina and Antarctica. Read More
  • Tour Type Group Tour
  • Activities Cruise & Kayaking and canoeing +2 more
  • Accommodation Hotel, Ship Cabin & Camping
  • Transport Cruise Ship
  • Age Range 18-99 yrs
  • Operated in English
days12 From US$ 10,395 View Tour
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Antarctic Express: Fly South, Cruise North

  • Best price guaranteed
  • No booking fees
10 day cruise trip to Punta Arenas, South Shetland Islands and 1 other destination in Argentina, Chile and Antarctica. Read More
  • Tour Type Cruise Tour
  • Activities Cruise
  • Accommodation Ship Cabin & Hotel
  • Transport Flight & Cruise Ship
  • Age Range 8-99 yrs
  • Operated in English
days10 From US$ 16,195 View Tour
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Antarctic Express: Cruise South, Fly North

  • Best price guaranteed
  • No booking fees
10 day cruise tour to Ushuaia, Drake Passage and 2 other destinations in Argentina, Chile and Antarctica. Read More
  • Tour Type Cruise Tour
  • Activities Cruise
  • Accommodation Ship Cabin & Hotel
  • Transport Flight & Cruise Ship
  • Age Range 8-99 yrs
  • Operated in English
days10 From US$ 16,795 View Tour
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Emperor Penguin Quest: Expedition to Snow Hill

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  • No booking fees
14 day cruise tour to Buenos Aires, Ushuaia and 3 other destinations in Argentina, Chile and Antarctica. Read More
  • Tour Type Cruise Tour
  • Activities Cruise
  • Accommodation Ship Cabin, Hotel & Hut
  • Transport Helicopter, Cruise Ship & Flight
  • Age Range 8-99 yrs
  • Operated in English
days14 From US$ 28,495 View Tour
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Galapagos Islands 5-Day Western Cruise Yacht Isabela II

  • Trip customizable
  • Best price guaranteed
5 day expedition tour in Ecuador, visiting Baltra Island, Bartolome Island and Santa Cruz. Read More
  • Tour Type Group Tour
  • Activities Expedition tours & Wildlife +2 more
  • Accommodation Ship Cabin
  • Transport Boat, Bus, Ferry, Yacht & Cruise Ship
  • Age Range 6-80 yrs
  • Operated in English, Spanish
days05 From US$ 4,514 View Tour
Next Departures
  • May 23
  • Jun 06
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Galapagos Islands 5-Day Northern Cruise Yacht Isabela II

  • Trip customizable
  • Best price guaranteed
5 day expedition trip in Ecuador, visiting Baltra Island, Isla Santiago and Isla Genovesa. Read More
  • Tour Type Group Tour
  • Activities Expedition tours & Cruise +1 more
  • Accommodation Ship Cabin
  • Transport Boat, Bus, Ferry, Yacht & Cruise Ship
  • Age Range 6-80 yrs
  • Operated in English, Spanish
days05 From US$ 4,514 View Tour
Next Departures
  • May 27
  • Jun 10
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Across the Antarctic Circle - M/V Greg Mortimer

  • Best price guaranteed
  • No booking fees
13 day cruise trip to Ushuaia, South Shetland Islands and 2 other destinations traveling through Argentina and Antarctica. Read More
  • Tour Type Small Group Tour
  • Activities Cruise & Polar expeditions and cruise
  • Accommodation Hotel, Ship Cabin, Hut & Resort
  • Transport Cruise Ship & Flight
  • Age Range 16-79 yrs
  • Operated in English
days13 From US$ 15,880 View Tour
Next Departures
  • Jan 16 10+ seats left
  • Feb 23 10+ seats left
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Classic Antarctica - Fly and Cruise - M/V Greg Mortimer

  • Best price guaranteed
  • No booking fees
13 day polar expeditions and cruise trip to Punta Arenas, King George Island and 3 other destinations in Argentina, Chile and Antarctica. Read More
  • Tour Type Small Group Tour
  • Activities Polar expeditions and cruise & Cruise
  • Accommodation Hotel, Ship Cabin & Hut
  • Transport Cruise Ship & Flight
  • Age Range 16-79 yrs
  • Operated in English
days13 From US$ 20,090 View Tour
Next Departures
  • Jan 26 10+ seats left
  • Feb 12 10+ seats left
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Antarctica In Depth - Expedition

  • Best price guaranteed
  • No booking fees
13 day wildlife trip to Ushuaia, South Shetland Islands and 2 other destinations traveling through Argentina and Antarctica. Read More
  • Tour Type Small Group Tour
  • Activities Wildlife & Polar expeditions and cruise +2 more
  • Accommodation Hotel, Resort & Ship Cabin
  • Transport Cruise Ship
  • Age Range 16-95 yrs
  • Operated in English
days13 From US$ 8,110 View Tour
Next Departures
  • Nov 11 10+ seats left
  • Dec 01 10+ seats left
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King Penguins of the Falklands and South Georgia - Expedition

  • Best price guaranteed
  • No booking fees
22 day active and outdoor trip through Montevideo, Falkland Islands, South Georgia and 3 other destinations in 4 different countries. Read More
  • Tour Type Small Group Tour
  • Activities Active and outdoor & Polar expeditions and cruise +1 more
  • Accommodation Hotel & Ship Cabin
  • Transport Cruise Ship
  • Age Range 16-79 yrs
  • Operated in English
days22 From US$ 13,520 View Tour
Next Departures
  • Oct 22 10+ seats left
Add to your Tour Wish List 18% OFFTODAY

Classic Galapagos: Southern Islands (Grand Queen Beatriz)

  • Best price guaranteed
  • No booking fees
10 day sailing, yachting and motor boating trip through Quito, Baltra Island, Isla Isabela and 6 other destinations in Ecuador. Read More
  • Tour Type Small Group Tour
  • Activities Sailing, yachting and motor boating & Wildlife +2 more
  • Accommodation Hotel
  • Transport Boat, Bus, Flight & Private Vehicle
  • Age Range 12-99 yrs
  • Operated in English
days10 From US$ 7,705 US$ 6,284
SavingUS$ 1,421
You've unlocked exclusive savings:
  • Brochure Price:US$ 7,705
  • Special Deal (18%):- US$ 1,421
  • Total Price from:US$ 6,284
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Next Departures
  • Jun 01 Only 2 seats left
  • Jun 15 Only 1 seat left
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Patagonia

  • Best price guaranteed
  • No booking fees
14 day natural landmarks sightseeing tour to Buenos Aires, El Calafate and 8 other destinations traveling through Argentina and Chile. Read More
  • Tour Type Group Tour
  • Activities Natural landmarks sightseeing & Cruise
  • Accommodation Hotel & Lodge
  • Transport Flight & Boat
  • Age Range 1-95 yrs
  • Operated in English
days14 From US$ 6,699 View Tour
Next Departures
  • Sep 30 10+ seats left
  • Oct 08 Only 2 seats left
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Journey to Antarctica: The White Continent aboard the National Geographic Resolution

  • Best price guaranteed
  • No booking fees
13 day cruise tour to Buenos Aires, Antarctic Peninsula and 2 other destinations traveling through Argentina and Antarctica. Read More
  • Tour Type Group Tour
  • Activities Cruise & Polar expeditions and cruise
  • Accommodation Hotel & Ship Cabin
  • Transport Cruise Ship
  • Age Range 1-95 yrs
  • Operated in English
days13 From US$ 16,549 View Tour
Next Departures
  • Feb 17 10+ seats left
Showing 43 - 56 of 62 results
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South America Cruise Reviews

5 - Excellent
Based on 66 customer reviews
At a loss to come up with adjectives!
5 - Excellent
  • Anonymous
“I am at a loss to come up with adjectives to describe this Expedition. Fantastico! The Expedition was Fantastico! The success of this Expedition was the result of the professionalism and hard work of the entire team. From the Hotel staff to the Ships crew and Expedition staff, this was truly a Team Effort. Everyone involved pulled together to make this a memorable experience. And everyone was in good humour from the moment we stepped aboard. And the Diamond did her part as well. She is well named - truly a Diamond.. Yours in loving Antarctica.”
Nothing but phenomenal things to say about this trip.
5 - Excellent
  • Anonymous
“We will be recommending this tour operator to anyone and everyone we meet. The guides made us feel like we finally found the types of people we could be forever friends with. It's hard to find such welcoming, genuine, and adventurous spirits like the ones you have on your team. We are sad to leave! As for the shore landings, Orne Harbour was the most beautiful place we've ever stepped foot on. The hike was incredible and the views were breathtaking. The island across from Port Lockroy was kind of a let down and did not need 45 minutes there at all. If Tom wasn't there to chat with, we honestly don't know what we would've done with our time on that island. We have nothing but phenomenal things to say about this trip. What an opportunity that you guys ensured to go above and beyond to make this worth the money and a once-in-a-lifetime adventure that we will never forget! Thank you!”
Highly Recommended!
5 - Excellent
  • Susanne & Miles Rowe
“Just wanted to take this opportunity to thank you and your team for a fantastic holiday in Argentina! We loved the country and the people. The highlights for us were Iguazu Falls, the wine tour & the little hotel in Mendoza and the Glacier trekking. The Glacier was amazing!!! All flights were on time and your guides were always there to meet and great. Please pass on a special thank you to Carla who looked after us in BA and kept in touch all through our travels. Thanks again, who did a fantastic job putting it all together and we will recommend you and your company to all our friends & family."”

South America Cruise Tours

Highlights of South America Cruise Tours

  • Embark on an Amazon river cruise tour in South America, encounter exotic wildlife, and connect with indigenous communities as you delve into the heart of the world’s largest rainforest.
  • Cruise through the Beagle Channel to witness Glacier Alley in Tierra del Fuego, where majestic glaciers meet the sea, creating a stunning display of frozen beauty amidst rugged landscapes.
  • Explore the historic Falkland Islands, home to rich avian life and tales of resilience.
  • Embark on a cruise tour adventure to South America that stops at several top sites. Take a trip to Iguazu Falls, and experience its grandeur from both Brazil and Argentina. Then, touch the skies at Machu Picchu, explore the Incan heritage in Cusco, and relish Lima's historic opulence—all UNESCO World Heritage Sites.
  • For the intrepid traveler, Antarctic expeditions offer a chance to explore the icy wilderness and its exceptional wildlife.
  • Encounter the untouched wonder of the Galapagos Islands, where the wildlife showcases the wonders of evolution.

Travel Tips for South America Cruise Tours

  • The best time for cruise tours in South America is during the summer months of the Southern Hemisphere, spanning from November to March. This period offers pleasant weather and vibrant landscapes, enhancing your cruise experience. However, keep in mind that prices might be higher during peak season.
  • Remember to pack comfortable walking shoes and a daypack for daily port visits.
  • Avoid overloading your itinerary with activities; take time to relax and savor the experience.
  • Consider arriving a day or two early to adjust to the local time and culture before setting sail.
  • Be flexible, as weather conditions can occasionally affect schedules, and trust in your captain’s backup plans.
  • Connect with knowledgeable crew members who can provide valuable insider tips to enhance your cruise tour to South America.
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