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Satisfy your wanderlust with one of our three-week tours in South America. Go on a memorable cycling trip through the picturesque villages of Peru, meeting locals and swapping stories with them along the way. Enjoy thrilling aerial adventures in the Andes in Argentina and get a bird’s eye view of PatagoniaTrek the evergreen Inca trail, gaze at the magnificence of Mount Fitz Roy and Mount Torre. Boat your way to the heart of the Amazon, where you will wake up to the sound of birdsongs in the morning. Have a gravity-defying moment while paragliding in La Paz before going on a cultural pilgrimage through the continent. Make sure that you tick Machu Picchu, Teatro Amazonas, Bahai Temple, and the towering monument dedicated to Christ the Redeemer off your bucket list.

Check all the boxes with a three-week South America itinerary. 

13 South America 3-week itineraries and tours

Add to your Tour Wish List 30% OFFTODAY

Southern Divide

  • Best price guaranteed
  • No booking fees
21 day cultural, religious and historic sites trip to Lima, Cusco and 1 other destinations traveling through Peru and Chile. Read More
  • Tour Type Small Group Tour
  • Activities Cultural, religious and historic sites & Explorer
  • Accommodation Hotel, Guest House & Resort
  • Transport Train, Flight, Boat, Bus, 4WD Jeep & Private Vehicle
  • Age Range 12-99 yrs
days21 From US$ 4,149 US$ 2,904
SavingUS$ 1,245
You've unlocked exclusive savings:
  • Brochure Price:US$ 4,149
  • Special Deal (30%):- US$ 1,245
  • Total Price from:US$ 2,904
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Next Departures
  • Dec 16 Only 5 seats left
  • Dec 23 Only 6 seats left
Tour with flexible booking policy
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Spirit of Shackleton

  • Best price guaranteed
  • No booking fees
21 day photography trip to Ushuaia, Beagle Channel Cruise and 3 other destinations in Argentina, Antarctica and England. Read More
  • Tour Type Group Tour
  • Activities Photography tours & Wildlife +6 more
  • Accommodation Hotel & Ship Cabin
  • Transport Bus, Private Vehicle & Cruise Ship
  • Age Range 12-99 yrs
days21 From US$ 16,899 View Tour
Next Departures
  • Jan 11 Only 2 seats left
  • Jan 11 Only 8 seats left
Tour with flexible booking policy
Add to your Tour Wish List 30% OFFTODAY

Peru Essentials

  • Best price guaranteed
  • No booking fees
21 day trekking trip to Lima, Ballestas Islands and Paracas National Reserve and 7 other destinations traveling through Peru and Bolivia. Read More
  • Tour Type Small Group Tour
  • Activities Trekking & Walking tours
  • Accommodation Hotel, Camping, Tent & Home-stay
  • Transport Bus, Train, Private Vehicle, Boat & Minibus
  • Age Range 15-99 yrs
days21 From US$ 3,205 US$ 2,243
SavingUS$ 962
You've unlocked exclusive savings:
  • Brochure Price:US$ 3,205
  • Special Deal (30%):- US$ 962
  • Total Price from:US$ 2,243
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Next Departures
  • Dec 24 10+ seats left
  • Feb 11 10+ seats left
Tour with flexible booking policy
Add to your Tour Wish List 20% OFFTODAY

Best of Peru, Argentina & Brazil

  • Best price guaranteed
  • No booking fees
21 day cultural, religious and historic sites trip to Lima, Ballestas Islands and Paracas National Reserve and 11 other destinations in Peru, Brazil and Argentina. Read More
  • Tour Type Small Group Tour
  • Activities Cultural, religious and historic sites
  • Accommodation Hotel
  • Transport Boat, Train, Bus, Private Vehicle, Flight & Minibus
  • Age Range 15-99 yrs
days21 From US$ 7,180 US$ 5,744
SavingUS$ 1,436
You've unlocked exclusive savings:
  • Brochure Price:US$ 7,180
  • Special Deal (20%):- US$ 1,436
  • Total Price from:US$ 5,744
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Next Departures
  • Mar 11 Only 8 seats left
  • Apr 08 Only 8 seats left
Tour with flexible booking policy
Add to your Tour Wish List 35% OFFTODAY

Lima to La Paz: Sandboarding & Sunsets

of 1 review
  • Best price guaranteed
  • No booking fees
I can only recommend this tour. It was great and I really enjoyed it. Lots to see. Great exploring t ...
  • Tour Type Small Group Tour
  • Activities Trekking & Cultural, religious and historic sites +1 more
  • Accommodation Hotel, Hostel, Home-stay & Camping
  • Transport Train, Bus, Flight, Boat & Private Vehicle
  • Age Range 18-39 yrs
days21 From US$ 2,899 US$ 1,884
SavingUS$ 1,015
You've unlocked exclusive savings:
  • Brochure Price:US$ 2,899
  • Special Deal (35%):- US$ 1,015
  • Total Price from:US$ 1,884
View Tour
Next Departures
  • Dec 11 10+ seats left
  • Dec 25 10+ seats left
Tour with flexible booking policy
Add to your Tour Wish List 10% OFFTODAY

Highlights of Argentina

of 1 review
  • Trip customizable
  • Best price guaranteed
We were able to see and do the most exciting things in Argentina! From trekking on glaciers ro dogsl ...
  • Tour Type Private Tour
  • Activities City sightseeing & Natural landmarks sightseeing +2 more
  • Accommodation Hotel & Ship Cabin
  • Transport Flight, Helicopter, Train, Bus, Yacht, Boat, Ferry, 4WD Jeep, Minibus & Cruise Ship
  • Age Range 12-99 yrs
days21 From US$ 2,819 US$ 2,537
SavingUS$ 282
You've unlocked exclusive savings:
  • Brochure Price:US$ 2,819
  • Special Deal (10%):- US$ 282
  • Total Price from:US$ 2,537
View Tour
Next Departures
  • Dec 19
  • Dec 26
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The Amazing Peru

  • Trip customizable
  • Best price guaranteed
21 day adventure tour through Lima, Nazca, Arequipa and 8 other destinations in Peru. Read More
  • Tour Type Small Group Tour
  • Activities Adventure & Hiking +5 more
  • Accommodation Guest House, Home-stay, Hotel & Sleeper Bus
  • Transport Boat, Bus, Flight, Private Vehicle & Train
  • Age Range 18-60 yrs
days21 From US$ 2,915 View Tour
Next Departures
  • Dec 06
  • Dec 07
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Highlights of South America - 21 days

  • Best price guaranteed
  • No booking fees
21 day wildlife tour through Rio de Janeiro, Foz Do Iguacu, Buenos Aires and 10 other destinations in 4 different countries. Read More
  • Tour Type Group Tour
  • Activities Wildlife
  • Accommodation Hotel & Luxury Hotel
  • Transport Flight, Private Vehicle, Train, Boat & Bus
  • Age Range 5-99 yrs
days21 From US$ 7,985 View Tour
Next Departures
  • Jan 09 10+ seats left
  • Feb 27 10+ seats left
Add to your Tour Wish List 35% OFFTODAY

Absolute Peru

  • Best price guaranteed
  • No booking fees
21 day wildlife tour through Lima, Paracas, Nazca and 11 other destinations in Peru. Read More
  • Tour Type Small Group Tour
  • Activities Wildlife & Trekking +3 more
  • Accommodation Hotel, Home-stay, Guest House & Camping
  • Transport Flight, Bus, Boat, Train & Private Vehicle
  • Age Range 12-99 yrs
days21 From US$ 3,999 US$ 2,599
SavingUS$ 1,400
You've unlocked exclusive savings:
  • Brochure Price:US$ 3,999
  • Special Deal (35%):- US$ 1,400
  • Total Price from:US$ 2,599
View Tour
Next Departures
  • Dec 10 Only 9 seats left
  • Dec 24 10+ seats left
Tour with flexible booking policy
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Falklands, South Georgia and Antarctica - M/V Sylvia Earle

  • Best price guaranteed
  • No booking fees
21 day polar expeditions and cruise trip to Ushuaia, South Georgia and 5 other destinations in Argentina, England and Antarctica. Read More
  • Tour Type Small Group Tour
  • Activities Polar expeditions and cruise
  • Accommodation Hotel, Hut & Ship Cabin
  • Transport Boat, Cruise Ship & Flight
  • Age Range 16-99 yrs
days21 From US$ 21,880 View Tour
Next Departures
  • Dec 19 10+ seats left
  • Nov 09 10+ seats left
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Falklands, South Georgia and Antarctica - M/V Greg Mortimer

  • Best price guaranteed
  • No booking fees
21 day cruise tour through Santiago, Antarctic Peninsula, South Shetland Islands and 5 other destinations in 5 different countries. Read More
  • Tour Type Small Group Tour
  • Activities Cruise & Polar expeditions and cruise
  • Accommodation Hotel, Hut, Ship Cabin & Tent
  • Transport Boat, Flight & Cruise Ship
  • Age Range 16-99 yrs
days21 From US$ 21,430 View Tour
Next Departures
  • Dec 27 10+ seats left
  • Mar 10 10+ seats left
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Falklands, South Georgia and Antarctica - Expedition

  • Best price guaranteed
  • No booking fees
21 day polar expeditions and cruise trip to Ushuaia, Drake Passage and 4 other destinations in Argentina, Antarctica and England. Read More
  • Tour Type Small Group Tour
  • Activities Polar expeditions and cruise & Active and outdoor +1 more
  • Accommodation Hotel, Resort & Ship Cabin
  • Transport Boat & Cruise Ship
  • Age Range 16-99 yrs
days21 From US$ 17,140 View Tour
Next Departures
  • Jan 11 10+ seats left
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Mountains to the Lakes

  • Trip customizable
  • Best price guaranteed
21 day mountains trip to Lima, Ballestas Islands and Paracas National Reserve and 9 other destinations traveling through Peru and Bolivia. Read More
  • Tour Type Small Group Tour
  • Activities Mountains
  • Accommodation Hotel, Camping, Guest House & Home-stay
  • Transport Boat, Train, Coach & Bus
  • Age Range 18-79 yrs
days21 From US$ 4,255 View Tour
Next Departures
  • Mar 25 10+ seats left
  • Apr 22 10+ seats left
Showing 1 - 13 of 13 results
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South America 3-Week Tour Reviews

5 - Excellent
Based on 66 customer reviews
Very Good
4 - Very Good
  • Francois B
“The camping equipment is solid and quite easy to assemble. The truck is very convenient and has almost everything it needs to provide a good experience. A lot of little details were taken care of.”
Excellent
5 - Excellent
  • Michael H
“The whole trip was excellent, I took part in both the Lima to Cuzco leg and again from Cafayate to Buenos Aires, and there were incredible opportunities during both legs. Personal highlights would be Machu Picchu, Arequipa, and the Estancia stay in Argentina.”
Excellent
5 - Excellent
  • Amardeep Kaur Sandhu H
“Jacopo has amazing organisational, communication and attention to detail - Noel is just a legend, he's an excellent driver and friend, has been very helpful as well and all of us enjoyed his company and learned to enjoy AC/DC after a while :)”