South America 21-Day Tours and Itineraries

Discover the best 21-Day multi-day tours in South America with Bookmundi. We offer a total of 16 South America 21-Day tours and itineraries with 70 customer reviews.

16 South America 21-day itineraries and tours

Add to your Tour Wish List

Spirit of Shackleton

  • Best price guaranteed
  • No booking fees
21 day photography tour to Ushuaia, Beagle Channel Cruise and 3 other destinations in Argentina, Antarctica and England. Read More
  • Tour Type Group Tour
  • Activities Photography tours & Wildlife +6 more
  • Accommodation Hotel & Ship Cabin
  • Transport Bus, Private Vehicle & Cruise Ship
  • Age Range 12-99 yrs
  • Operated in English
days21 From US$ 18,199 View Tour
Next Departures
  • Jan 11 Only 2 seats left
Tour with flexible booking policy
Add to your Tour Wish List

Southern Divide

  • Best price guaranteed
  • No booking fees
21 day cultural, religious and historic sites trip to Lima, Cusco and 1 other destinations traveling through Peru and Chile. Read More
  • Tour Type Small Group Tour
  • Activities Cultural, religious and historic sites & Explorer
  • Accommodation Hotel, Guest House & Resort
  • Transport Train, Flight, Boat, Bus, 4WD Jeep & Private Vehicle
  • Age Range 12-99 yrs
  • Operated in English
days21 From US$ 4,349 View Tour
Next Departures
  • Jun 16 Only 10 seats left
  • Jun 30 Only 7 seats left
Tour with flexible booking policy
Add to your Tour Wish List 30% OFFTODAY

Peru Essentials

  • Best price guaranteed
  • No booking fees
21 day trekking tour to Lima, Ballestas Islands and Paracas National Reserve and 7 other destinations traveling through Peru and Bolivia. Read More
  • Tour Type Small Group Tour
  • Activities Trekking & Walking tours
  • Accommodation Hotel, Camping & Home-stay
  • Transport Bus, Train, Private Vehicle, Boat & Minibus
  • Age Range 15-99 yrs
  • Operated in English
days21 From US$ 3,955 US$ 2,768
SavingUS$ 1,187
You've unlocked exclusive savings:
  • Brochure Price:US$ 3,955
  • Special Deal (30%):- US$ 1,187
  • Total Price from:US$ 2,768
View Tour
Next Departures
  • Jun 17 10+ seats left
  • Jul 08 10+ seats left
Add to your Tour Wish List 30% OFFTODAY

Lima to La Paz: Sandboarding & Sunsets

of 1 review
  • Best price guaranteed
  • No booking fees
I can only recommend this tour. It was great and I really enjoyed it. Lots to see. Great exploring t ...
  • Tour Type Small Group Tour
  • Activities Trekking & Cultural, religious and historic sites +1 more
  • Accommodation Hotel, Hostel, Home-stay, Camping & Lodge
  • Transport Train, Bus, Flight, Boat & Private Vehicle
  • Age Range 18-39 yrs
  • Operated in English
days21 From US$ 3,449 US$ 2,414
SavingUS$ 1,035
You've unlocked exclusive savings:
  • Brochure Price:US$ 3,449
  • Special Deal (30%):- US$ 1,035
  • Total Price from:US$ 2,414
View Tour
Next Departures
  • Jun 11 Only 5 seats left
  • Jun 18 Only 2 seats left
Tour with flexible booking policy
Add to your Tour Wish List 10% OFFTODAY

Best of Peru, Argentina & Brazil

  • Best price guaranteed
  • No booking fees
21 day cultural, religious and historic sites tour to Lima, Ballestas Islands and Paracas National Reserve and 11 other destinations in Peru, Brazil and Argentina. Read More
  • Tour Type Small Group Tour
  • Activities Cultural, religious and historic sites
  • Accommodation Hotel
  • Transport Boat, Train, Bus, Private Vehicle, Flight & Minibus
  • Age Range 15-99 yrs
  • Operated in English
days21 From US$ 8,850 US$ 7,965
SavingUS$ 885
You've unlocked exclusive savings:
  • Brochure Price:US$ 8,850
  • Special Deal (10%):- US$ 885
  • Total Price from:US$ 7,965
View Tour
Next Departures
  • Jun 24 Only 6 seats left
  • Jul 15 Only 4 seats left
Add to your Tour Wish List 30% OFFTODAY

Absolute Peru

  • Best price guaranteed
  • No booking fees
21 day wildlife trip through Lima, Paracas, Nazca and 11 other destinations in Peru. Read More
  • Tour Type Small Group Tour
  • Activities Wildlife & Trekking +3 more
  • Accommodation Hotel, Home-stay, Guest House & Camping
  • Transport Flight, Bus, Boat, Train & Private Vehicle
  • Age Range 12-99 yrs
  • Operated in English
days21 From US$ 4,949 US$ 3,464
SavingUS$ 1,485
You've unlocked exclusive savings:
  • Brochure Price:US$ 4,949
  • Special Deal (30%):- US$ 1,485
  • Total Price from:US$ 3,464
View Tour
Next Departures
  • Jun 14 Only 6 seats left
  • Jun 28 Only 9 seats left
Tour with flexible booking policy
Add to your Tour Wish List

Highlights of Argentina

of 5 reviews
  • Trip customizable
  • Best price guaranteed
My partner and I have just returned from a 4-week trip throughout Chile and Argentina. The team real ...
  • Tour Type Private Tour
  • Activities City sightseeing & Natural landmarks sightseeing +2 more
  • Accommodation Hotel
  • Transport Flight, Helicopter, Train, Bus, Yacht, Boat, Ferry, 4WD Jeep & Minibus
  • Age Range 12-99 yrs
  • Operated in English
days21 From US$ 2,819 View Tour
Next Departures
  • Sep 18
  • Sep 25
Add to your Tour Wish List

Highlights of South America - 21 days

  • Best price guaranteed
  • No booking fees
21 day wildlife trip through Rio de Janeiro, Foz Do Iguacu, Buenos Aires and 10 other destinations in 4 different countries. Read More
  • Tour Type Group Tour
  • Activities Wildlife
  • Accommodation Hotel & Luxury Hotel
  • Transport Flight, Private Vehicle, Train, Boat & Bus
  • Age Range 5-99 yrs
  • Operated in English
days21 From US$ 7,985 View Tour
Next Departures
  • Jul 31 10+ seats left
  • Sep 04 10+ seats left
Add to your Tour Wish List

The Amazing Peru

  • Trip customizable
  • Best price guaranteed
21 day adventure trip through Lima, Nazca, Arequipa and 8 other destinations in Peru. Read More
  • Tour Type Small Group Tour
  • Activities Adventure & Hiking +5 more
  • Accommodation Guest House, Home-stay, Hotel & Sleeper Bus
  • Transport Boat, Bus, Flight, Private Vehicle & Train
  • Age Range 18-60 yrs
  • Operated in English
days21 From US$ 2,915 View Tour
Next Departures
  • Jul 08
  • Jul 09
Add to your Tour Wish List

Rio de Janeiro to Santiago Travel Pass

  • Best price guaranteed
  • No booking fees
21 day natural landmarks sightseeing trip to Rio de Janeiro, Ilha Grande and 9 other destinations in Brazil, Chile and Argentina. Read More
  • Activities Natural landmarks sightseeing & Beaches +3 more
  • Accommodation Hotel
  • Transport Bus, Ferry, Boat & Train
  • Age Range 18-99 yrs
  • Operated in English
days21 From US$ 1,662 View Tour
Next Departures
  • Jun 12 10+ seats left
  • Jun 13 10+ seats left
Add to your Tour Wish List

San Jose to Antigua Travel Pass

  • Best price guaranteed
  • No booking fees
21 day adventure trip through San Jose, Manuel Antonio National Park, Manuel Antonio and 10 other destinations in 5 different countries. Read More
  • Activities Adventure & Natural landmarks sightseeing +1 more
  • Accommodation Home-stay & Hostel
  • Transport 4WD Jeep, Boat & Ferry
  • Age Range 18-99 yrs
  • Operated in English
days21 From US$ 1,487 View Tour
Next Departures
  • Jun 12 10+ seats left
  • Jun 13 10+ seats left
Add to your Tour Wish List

Mountains to the Lakes

  • Trip customizable
  • Best price guaranteed
21 day mountains tour to Lima, Ballestas Islands and Paracas National Reserve and 9 other destinations traveling through Peru and Bolivia. Read More
  • Tour Type Small Group Tour
  • Activities Mountains
  • Accommodation Hotel, Camping, Guest House & Home-stay
  • Transport Boat, Train, Coach & Bus
  • Age Range 18-79 yrs
  • Operated in English
days21 From US$ 4,255 View Tour
Next Departures
  • Jun 17 10+ seats left
  • Jul 15 10+ seats left
Showing 1 - 14 of 16 results
Filters

South America 21-Day Tour Reviews

5 - Excellent
Based on 70 customer reviews
Excellent Trip!
5 - Excellent
  • Poh
“We had an excellent trip to Argentina and Chile, including Patagonia, and to Brazil and the Antartica. During the long trip, Alvaro was always responsive and helpful. Having a reliable agent matters in South America due to the changing flight connections, which Alvaro helped manage seamlessly. The tour guides chosen were excellent and the tours recommended were very enjoyable. Most importantly, it had been a joy dealing with Alvaro because he is effective and professional.”
Excellent
5 - Excellent
  • Amardeep Kaur Sandhu H
“Jacopo has amazing organisational, communication and attention to detail - Noel is just a legend, he's an excellent driver and friend, has been very helpful as well and all of us enjoyed his company and learned to enjoy AC/DC after a while :)”
Had a great tour - really enjoyable!
5 - Excellent
  • Anonymous
“I can only recommend this tour. It was great and I really enjoyed it. Lots to see. Great exploring the Inca Trail. Thank you very much for all the arrangements and a splendid tour!”