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See the top South America 21-Day tours and itineraries. Select from 14 21-Day tours in South America with a total of 66 genuine reviews. Each of Bookmundi’s 21-Day South America itineraries are carefully handpicked.

14 South America 21-day itineraries and tours

Add to your Tour Wish List 5% OFFTODAY

Southern Divide

  • Best price guaranteed
  • No booking fees
21 day cultural, religious and historic sites tour to Lima, Cusco and 13 other destinations in Peru, Chile and Bolivia. Read More
  • Tour Type Small Group Tour
  • Operator G Adventures Active 13 hours ago Premier This operator is consistently delivering tours which receive customer ratings above 4.5 on average.
  • Activities Cultural, religious and historic sites & Explorer
  • Accommodation Hotel, Resort & Guest House
  • Transport Train, Flight, Boat, Bus, 4WD Jeep & Private Vehicle
  • Age Range1+ years old
days21 From US$ 3,999 US$ 3,799
SavingUS$ 200
You've unlocked exclusive savings:
  • Brochure Price:US$ 3,999
  • Bookmundi Savings (5%):- US$ 200
  • Total Price from:US$ 3,799
View Tour
Next Departures
  • Aug 12 Only 6 seats left
  • Sep 02 Only 3 seats left
Tour with flexible booking policy
Add to your Tour Wish List 5% OFFTODAY

Spirit of Shackleton

  • Best price guaranteed
  • No booking fees
21 day photography trip to Ushuaia, Beagle Channel Cruise and 4 other destinations in Argentina, Antarctica and Falkland Islands. Read More
  • Tour Type Small Group Tour
  • Operator G Adventures Active 13 hours ago Premier This operator is consistently delivering tours which receive customer ratings above 4.5 on average.
  • Activities Photography tours & Wildlife +6 more
  • Accommodation Hotel & Ship Cabin
  • Transport Bus, Private Vehicle & Cruise Ship
  • Age Range1+ years old
days21 From US$ 23,899 US$ 22,704
SavingUS$ 1,195
You've unlocked exclusive savings:
  • Brochure Price:US$ 23,899
  • Bookmundi Savings (5%):- US$ 1,195
  • Total Price from:US$ 22,704
View Tour
Next Departures
  • Jan 11 Only 2 seats left
Tour with flexible booking policy
Add to your Tour Wish List 25% OFFTODAY

Antarctica, South Georgia & Falklands Odyssey (Ocean Endeavour)

  • Best price guaranteed
  • No booking fees
21 day wildlife trip to Ushuaia, Drake Passage and 5 other destinations in Argentina, Antarctica and Falkland Islands. Read More
  • Tour Type Group Tour
  • Operator Intrepid Travel Active 6 hours ago Premier This operator is consistently delivering tours which receive customer ratings above 4.5 on average.
  • Activities Wildlife & Polar expeditions and cruise +1 more
  • Accommodation Ship Cabin & Hotel
  • Transport Cruise Ship
  • Age Range8+ years old
days21 From US$ 21,290 US$ 15,967
SaveUS$ 6,121
View Tour
Next Departures
  • Mar 10 10+ seats left
Tour with flexible booking policy
Add to your Tour Wish List 24% OFFTODAY

Lima to La Paz: Sandboarding & Sunsets

of 1 review
  • Best price guaranteed
  • No booking fees
I can only recommend this tour. It was great and I really enjoyed it. Lots to see. Great exploring t ...
  • Tour Type Small Group Tour
  • Operator G Adventures Active 13 hours ago Premier This operator is consistently delivering tours which receive customer ratings above 4.5 on average.
  • Activities Trekking & Cultural, religious and historic sites +1 more
  • Accommodation Hotel, Hostel, Home-stay & Camping
  • Transport Train, Bus, Flight, Boat & Private Vehicle
  • Age Range18-39 yrs
days21 From US$ 3,049 US$ 2,317
SavingUS$ 732
You've unlocked exclusive savings:
  • Brochure Price:US$ 3,049
  • Bookmundi Savings (5%):- US$ 122
  • Special Deal (20%):- US$ 610
  • Total Price from:US$ 2,317
View Tour
Next Departures
  • Jul 10 Only 4 seats left
  • Aug 07 10+ seats left
Tour with flexible booking policy
Add to your Tour Wish List 25% OFFTODAY

Peru Essentials

  • Best price guaranteed
  • No booking fees
21 day trekking trip to Lima, Ballestas Islands and Paracas National Reserve and 7 other destinations traveling through Peru and Bolivia. Read More
  • Tour Type Small Group Tour
  • Operator Intrepid Travel Active 6 hours ago Premier This operator is consistently delivering tours which receive customer ratings above 4.5 on average.
  • Activities Trekking & Walking tours
  • Accommodation Hotel, Camping, Tent & Home-stay
  • Transport Bus, Train, Private Vehicle, Boat & Minibus
  • Age Range15+ years old
days21 From US$ 3,095 US$ 2,321
SaveUS$ 890
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Next Departures
  • Jun 18 10+ seats left
  • Jul 16 10+ seats left
Tour with flexible booking policy
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The Amazing Peru

  • Trip customizable
  • Best price guaranteed
21 day adventure trip through Lima, Nazca, Arequipa and 8 other destinations in Peru. Read More
  • Tour Type Small Group Tour
  • Operator Around Travel Adventures Active 9 hours ago
  • Activities Adventure & Hiking +5 more
  • Accommodation Guest House, Home-stay, Hotel & Sleeper Bus
  • Transport Boat, Bus, Flight, Private Vehicle & Train
  • Age Range18-60 yrs
days21 From US$ 2,915 View Tour
Next Departures
  • Jun 25
  • Jun 26
Add to your Tour Wish List 5% OFFTODAY

Highlights of South America - 21 days

  • Best price guaranteed
  • No booking fees
21 day wildlife trip through Rio de Janeiro, Foz Do Iguacu, Buenos Aires and 10 other destinations in 4 different countries. Read More
  • Tour Type Group Tour
  • Operator On The Go Tours Active 5 hours ago
  • Activities Wildlife
  • Accommodation Hotel & Luxury Hotel
  • Transport Flight, Private Vehicle, Train, Boat & Bus
  • Age Range18+ years old
days21 From US$ 9,035 US$ 8,583
SavingUS$ 452
You've unlocked exclusive savings:
  • Brochure Price:US$ 9,035
  • Bookmundi Savings (5%):- US$ 452
  • Total Price from:US$ 8,583
View Tour
Next Departures
  • Aug 01 Only 8 seats left
  • Sep 05 Only 8 seats left
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Best of Peru, Argentina & Brazil

  • Best price guaranteed
  • No booking fees
21 day cultural, religious and historic sites trip to Lima, Ballestas Islands and Paracas National Reserve and 11 other destinations in Peru, Brazil and Argentina. Read More
  • Tour Type Small Group Tour
  • Operator Intrepid Travel Active 6 hours ago Premier This operator is consistently delivering tours which receive customer ratings above 4.5 on average.
  • Activities Cultural, religious and historic sites
  • Accommodation Hotel
  • Transport Boat, Train, Bus, Private Vehicle, Flight & Minibus
  • Age Range15+ years old
days21 From US$ 7,120
SaveUS$ 356
View Tour
Next Departures
  • Jul 16 Only 4 seats left
  • Aug 06 Only 4 seats left
Tour with flexible booking policy
Add to your Tour Wish List 24% OFFTODAY

Absolute Peru

  • Best price guaranteed
  • No booking fees
21 day wildlife tour through Lima, Paracas, Nazca and 11 other destinations in Peru. Read More
  • Tour Type Small Group Tour
  • Operator G Adventures Active 13 hours ago Premier This operator is consistently delivering tours which receive customer ratings above 4.5 on average.
  • Activities Wildlife & Trekking +3 more
  • Accommodation Hotel, Home-stay, Guest House & Camping
  • Transport Flight, Bus, Boat, Train & Private Vehicle
  • Age Range1+ years old
days21 From US$ 4,399 US$ 3,343
SavingUS$ 1,056
You've unlocked exclusive savings:
  • Brochure Price:US$ 4,399
  • Bookmundi Savings (5%):- US$ 176
  • Special Deal (20%):- US$ 880
  • Total Price from:US$ 3,343
View Tour
Next Departures
  • Jul 02 Only 9 seats left
  • Jul 16 Only 1 seat left
Tour with flexible booking policy
Add to your Tour Wish List

Highlights of Argentina

of 1 review
  • Trip customizable
  • Best price guaranteed
We were able to see and do the most exciting things in Argentina! From trekking on glaciers ro dogsl ...
  • Tour Type Private Tour
  • Operator Beyond BA LATAM Active 25 minutes ago
  • Activities City sightseeing & Natural landmarks sightseeing +2 more
  • Accommodation Hotel
  • Transport Flight, Helicopter, Train, Bus, Yacht, Boat, Ferry, 4WD Jeep & Minibus
  • Age Range12+ years old
days21 From US$ 2,819 View Tour
Next Departures
  • Sep 19
  • Sep 26
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Falklands, South Georgia and Antarctica - M/V Sylvia Earle

  • Best price guaranteed
  • No booking fees
21 day polar expeditions and cruise trip to Ushuaia, Drake Passage and 5 other destinations in Argentina, Antarctica and Falkland Islands. Read More
  • Tour Type Small Group Tour
  • Operator Explore Active 11 hours ago Premier This operator is consistently delivering tours which receive customer ratings above 4.5 on average.
  • Activities Polar expeditions and cruise
  • Accommodation Hotel, Hut & Ship Cabin
  • Transport Boat, Cruise Ship & Flight
  • Age Range14+ years old
days21 From US$ 29,580 View Tour
Next Departures
  • Dec 19 10+ seats left
Add to your Tour Wish List

Falklands, South Georgia and Antarctica - Expedition

  • Best price guaranteed
  • No booking fees
21 day polar expeditions and cruise tour to Ushuaia, Drake Passage and 4 other destinations in Argentina, Antarctica and Falkland Islands. Read More
  • Tour Type Small Group Tour
  • Operator Explore Active 11 hours ago Premier This operator is consistently delivering tours which receive customer ratings above 4.5 on average.
  • Activities Polar expeditions and cruise & Active and outdoor +1 more
  • Accommodation Hotel, Resort & Ship Cabin
  • Transport Boat & Cruise Ship
  • Age Range14+ years old
days21 From US$ 19,030 View Tour
Next Departures
  • Jan 11 10+ seats left
Add to your Tour Wish List

Mountains to the Lakes

  • Trip customizable
  • Best price guaranteed
21 day mountains trip to Lima, Ballestas Islands and Paracas National Reserve and 9 other destinations traveling through Peru and Bolivia. Read More
  • Tour Type Small Group Tour
  • Operator Encounters Travel
  • Activities Mountains
  • Accommodation Hotel, Camping, Guest House & Home-stay
  • Transport Boat, Train & Coach
  • Age Range1+ years old
days21 From US$ 2,970 View Tour
Next Departures
  • Jun 10 10+ seats left
  • Jul 10 10+ seats left
Add to your Tour Wish List

Antarctica, South Georgia and Falklands Explorer (Ocean Endeavour)

  • Best price guaranteed
  • No booking fees
21 day polar expeditions and cruise tour to Ushuaia, Drake Passage and 4 other destinations in Argentina, Antarctica and Falkland Islands. Read More
  • Tour Type Group Tour
  • Operator Intrepid Travel Active 6 hours ago Premier This operator is consistently delivering tours which receive customer ratings above 4.5 on average.
  • Activities Polar expeditions and cruise
  • Accommodation Hotel, Camping & Ship Cabin
  • Transport Cruise Ship & Boat
  • Age Range8+ years old
days21 From US$ 14,990
SaveUS$ 750
View Tour
Next Departures
  • Jan 20 Only 5 seats left
  • Nov 20 10+ seats left
Tour with flexible booking policy
Showing 1 - 14 of 14 results
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South America 21-Day Tour Reviews

5 - Excellent
Based on 66 customer reviews
Excellent
5 - Excellent
  • Michael H
“The whole trip was excellent, I took part in both the Lima to Cuzco leg and again from Cafayate to Buenos Aires, and there were incredible opportunities during both legs. Personal highlights would be Machu Picchu, Arequipa, and the Estancia stay in Argentina.”
Excellent
5 - Excellent
  • Amardeep Kaur Sandhu H
“Jacopo has amazing organisational, communication and attention to detail - Noel is just a legend, he's an excellent driver and friend, has been very helpful as well and all of us enjoyed his company and learned to enjoy AC/DC after a while :)”
Excellent
5 - Excellent
  • Louise P
“The drivers were both personable, professional and just lovely people to be around. They dealt with quite a few unpredictable problems (hail in the Moon Valley, several-hour border delays, etc.) incredibly well and I am glad they were both our crew.”
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